Symposium
From Risk Prediction and Simulation to Treatment - Developing Precision Medicine through Collaboration with Medical Engineering –
JAPANESE
| Chairperson: | Masanori Nakamura（Nagoya Institute of Technology） |
| Masao Yoshizumi （Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical Science, Hiroshima University） |
On 20th January 2015, the “Precision Medicine Initiative” was announced in President Obama's State of the Union address. Precision medicine (PM) involves individual medical care according to an individual patient's data. It can be used for cancer treatment: The most effective treatment for an individual is selected with the aid of artificial intelligence, based on information about the cancer genome.
PM opens up a range of possibilities in relation to the cardiovascular domain of medicine. For example, hemodynamics is very different for each patient. Although it is not easy to grasp a particular patient’s hemodynamics accurately with measurement, it can be simulated with computers. Fractional flow reserve (FFR) derived from coronary computed tomographic angiography is a diagnostic index of coronary artery stenosis that can be obtained with such patient-specific flow simulations. FFR-CT (fractional flow reserve-computed tomography) is now starting to spread across the world as the first simulation-based index in the cardiovascular domain.
In the future, if we can predict retrograde blood flow by simulation before coronary artery bypass surgery, it will be a useful guide for choosing the appropriate surgical procedure. Even in aneurysms, prediction of rupture may be possible not only by size and shape, but also by estimation of wall stress.
Now that the Japanese Circulation Society and the Japan Society of Mechanical Engineers have concluded a collaborative agreement, there is increasing momentum for medical science to incorporate engineering technologies to create a new medical field. In this session, we will discuss basic technologies and device development that will open up the precision medicine field in the cardiovascular domain through collaboration with medical engineers.
PM opens up a range of possibilities in relation to the cardiovascular domain of medicine. For example, hemodynamics is very different for each patient. Although it is not easy to grasp a particular patient’s hemodynamics accurately with measurement, it can be simulated with computers. Fractional flow reserve (FFR) derived from coronary computed tomographic angiography is a diagnostic index of coronary artery stenosis that can be obtained with such patient-specific flow simulations. FFR-CT (fractional flow reserve-computed tomography) is now starting to spread across the world as the first simulation-based index in the cardiovascular domain.
In the future, if we can predict retrograde blood flow by simulation before coronary artery bypass surgery, it will be a useful guide for choosing the appropriate surgical procedure. Even in aneurysms, prediction of rupture may be possible not only by size and shape, but also by estimation of wall stress.
Now that the Japanese Circulation Society and the Japan Society of Mechanical Engineers have concluded a collaborative agreement, there is increasing momentum for medical science to incorporate engineering technologies to create a new medical field. In this session, we will discuss basic technologies and device development that will open up the precision medicine field in the cardiovascular domain through collaboration with medical engineers.
