CONGRESS ABSTRACTS have been published as a supplement of the international online journal, ACER (Alcoholism: Clinical and Experimental Research) in the Wiley Online Library since August 30, 2018 at https://onlinelibrary.wiley.com/toc/15300277/2018/42/S2.
- Plenary Speakers
- Symposium
- ISBRA-WHO Workshop
- The 13th International Symposium on ALPD and Cirrhosis
Plenary Speakers
Plenary Lecture 1
Monday, September 10, 9:00-9:45
Alcohol policy development and research:
A complex interface
- Vladimir Poznyak
- Department of Mental Health and Substance Abuse, World Health Organization, Geneva, Switzerland
Vladimir Poznyak is a Coordinator of Management of Substance Abuse unit at the World Health Organization (WHO) in Geneva, and in this capacity he is responsible for coordination of normative, advocacy, research and country support activities on alcohol, drugs and addictive behaviors in WHO headquarters. A medical doctor and psychiatrist by professional background, Dr Poznyak received his PhD from All-Union Center of Medical and Biological Problems of Addiction Medicine in Moscow, Russian Federation, and his research at that time was focused on gender differences in alcohol dependence. Dr Poznyak has been at the forefront of the WHO Secretariat’s work on development and implementation of the WHO Global strategy to reduce the harmful use of alcohol and on addressing public health dimensions of the world drug problem. In recent years Dr Poznyak coordinated the work on 11th revision of the International Classification of Diseases (ICD) for disorders due to substance use and addictive behaviors.
Psychoactive, toxic and dependence-producing properties of alcohol are well documented, and recent research findings expand the list of health conditions with causal relationship to alcohol consumption. In spite of around 3 million deaths attributable worldwide to alcohol every year and around 250 million people affected by alcohol use disorders, effective alcohol control policies lack strong support in many societies and jurisdictions. The WHO Global strategy to reduce the harmful use of alcohol is the only global non-binding policy framework on alcohol that was negotiated and agreed at the intergovernmental level. The recent global policy developments, including Sustainable Development Goals 2030 with special health target on substance abuse and strategies for prevention and control of Noncommunicable Diseases (NCDs) create new opportunities for effective alcohol control. Research findings on effectiveness and cost-effectiveness of policy options prompted development of “best buy” concept that includes feasible policies and interventions with an average cost-effectiveness ration of ≤ 1$ 100/DALY. For reducing the harmful use of alcohol these policy options include increase in excise taxes and prices of alcoholic beverages, reduction in physical availability of retailed alcohol and comprehensive restrictions or bans on alcohol advertising. Screening and brief interventions (SBI) for hazardous and harmful drinking has good cost-effectiveness ratio, but their implementation in health systems is limited. The 11th revision of the International Classification of Diseases, released in June 2018, is expected to facilitate implementation of alcohol-focused interventions in health services. The global data on implementation of alcohol policy options indicate that research efforts do not necessarily translate into science-based policy developments, and factors influencing the complex interface between research and alcohol policy development will be discussed in the presentation.
Plenary Lecture 2
Tuesday, September 11, 8:15-9:00
ISBRA Tabakoff Award Lecture
Developing neuroscience based treatments for alcohol addiction - Challenges and prospects
- Markus A. Heilig
- Center for Social and Affective Neuroscience, Sweden
Markus Heilig received his MD and PhD from Lund University, Sweden, 1986 and 1989, resp, and was a post-doc at The Scripps Research Institute, LaJolla, CA 1990 - 1992. Upon returning to Sweden and completing clinical training in psychiatry, he served at the Karolinska Institute, Stockholm, Sweden, in various clinical and academic leadership capacities until 2004. Between 2004 – 2015, he was the chief of intramural clinical and translational research at the US National Inst on Alcohol Abuse and Alcoholism. In 2015, he was recruited back to Sweden as the founding director of the Center for Social and Affective Neuroscience at Linköping Univ, in a joint initiative of the Swedish Research Council, the University and the Region.
Heilig's research is centered on regulation of negative effect, as it applies to affective, anxiety and addictive disorders. He has published more than 250 peer reviewed papers, including in leading journals such as Science, Lancet, PNAS and others. His work has been cited >10000 times, resulting in an H-index of about 60. Current efforts in the Heilig lab are focused on identifying novel mechanisms for pharmacotherapy of addiction, and developing these from preclinical target discovery and validation to early human proof-of-concept trials. Currently pursued targets include systems involved in stress- and negative effect such as neurokinins, nociceptin, glutamate and cannabinoids. Recently, his laboratory has expanded the scope of its research incorporate the neurobiology of choosing between alcohol and natural rewards, and how social factors influence these behaviors.Neurobiological research on addictive disorders has grown exponentially in the past two decades. It has also become increasingly sophisticated in its ability to identify neural circuits and molecular mechanisms behind drug seeking and taking. These advances have fueled hopes that novel, neuroscience based treatments would emerge and transform treatment of alcohol addiction. That hope has not yet materialized. Existing medications for alcohol addiction provide proof-of-principle for pharmacological treatment of this disorder, but their discovery precedes the neuroscience revolution, and they have not been adopted broadly enough to transform clinical practice.
This talk will review the ups, downs and new ups over two decades of translational work attempting to identify and target novel mechanisms for treatment of alcohol addiction. The first theme will discuss the limitations of focusing on brain reward mechanisms as therapeutic targets, and review our work on reprogramming of the transcriptome within key brain structures as a mechanism behind long-term neuroadaptations that fundamentally change the incentives behind alcohol seeking. The second theme will discuss the limitations of studying drug seeking in isolation. It will introduce the critical importance of studying alcohol seeking in the context of availability of natural rewards, and of individual vulnerability. Implications for medications development will be discussed.
Plenary Lecture 3
Tuesday, September 11, 9:00-9:45
Burden of disease caused by alcohol and alcohol use disorders – What do we know and where do we go?
- Jurgen Rehm
- Centre for Addiction and Mental Health, Toronto, Canada
Jürgen Rehm, Ph.D., has been appointed the Inaugural Chair for Addiction Policy at the Dalla Lana School of Public Health of the University of Toronto (Canada). In addition, he holds positions at the Centre for Addiction and Mental Health as Senior Director of the Institute for Mental Health Policy Research, and at the Institute for Clinical Psychology and Psychotherapy of the Technical University Dresden (Germany). Dr. Rehm has published more than 900 peer-reviewed journal articles in substance use research; and is listed among the Thompson Reuters/Clarivate most highly cited in his field (top 1% with respect to impact as measured by citations). He has been awarded the Jellinek and the European Addiction Research Awards.
Alcohol use has long been known to be a major risk factor for burden of disease and injury. The newest global and regional estimates of alcohol-attributable burden of disease as measured in deaths, years of life lost and disability adjusted life years will be presented, with emphasis on alcohol-attributable infectious disease, gastrointestinal disease and injuries.
The contribution of heavy drinking occasions and liver disease in the etiology of alcohol-attributable disease burden will be highlighted, as well as the interaction with between alcohol use and socioeconomic status and poverty. As a specific example of the latter, we will highlight the contribution of alcohol to the current stagnation of life expectancy in the USA.
Plenary Lecture 4
Tuesday, September 11, 13:50-14:35
Liver parenchymal cells and sinusoidal cells: Cell sociology in alcoholic liver disease
- Yoshiyuki Takei
- Department of Gastroenterology, Mie University School of Medicine, Japan
Yoshiyuki Takei, MD, PhD is Vice President of Mie University and Professor and Chairman of the Department of Gastroenterology, Mie University Graduate School of Medicine. Following his training as a hepatology specialist at the First Department of Medicine, Osaka University and the University of North Carolina at Chapel Hill (mentor: Late Prof. Ronald G Thurman), his translational and clinical investigations have focused on alcoholic liver disease and non-alcoholic fatty liver disease with special interest in the interaction and crosstalk between hepatocytes and non-parenchymal cells. He has published more than 300 peer-reviewed articles in respected international journals.
He is a long-time member of the ISBRA and was the Vice Chairman of the Local Organizing Committee of the ISBRA Congress in 2012. He has also served on the boards of the ISBRA and the Japan Society of Hepatology.Since the direct hepatotoxicity of ethanol was demonstrated by Charles Lieber almost half a century ago, significant progress has been made in research on the mechanism of alcohol liver disease (ALD). Consequently, the mechanism of ALD is considered to be diverse and multifaceted. In the late 1980s, it was proposed that alcohol is not only the direct toxicant to liver parenchymal cells, but also targets a variety of liver sinusoidal cells including Kupffer cells, stellate cells and sinusoidal endothelial cells (SECs). This hypothesis led to the general theory that alcohol-induced liver damage is a result of multiple, complex parallel processes. Ethanol-induced factors that communicate stress signals between hepatocytes and non-parenchymal cells initiate and perpetuate the pathological processes responsible for liver damage and disease progression to alcoholic hepatitis and cirrhosis. For example, at high concentrations, ethanol evokes endothelin-1 expression in SECs and causes contraction of the hepatic sinusoid leading to disturbed hepatic microcirculation. Moreover, ethanol increases gut-derived endotoxins (pathogen-associated molecular patterns), leading to the activation of Kupffer cells, culminating in the overproduction of toxic mediators such as tumor necrosis factor-α. Thus, interaction and crosstalk between hepatocytes and non-parenchymal cells appear to be crucial to the pathogenesis of ALD.
Plenary Lecture 5
Wednesday, September 12, 9:00-9:45
On the Use of Cognitive Training in the Treatment of Alcohol Use Disorders
- Reinout W. Wiers
- Professor of Developmental Psychopathology, Addiction Development and Psychopathology (ADAPT) Lab; Chair of Developmental Psychology, Faculteitshoogleraar FMG UvA; and Department of Psychology, Universiteit van Amsterdam, the Netherlands
Professor Reinout W. Wiers is professor of developmental psychopathology and distinguished faculty professor at the University of Amsterdam (UvA). He is senior editor of the journal Addiction, and on the editorial board of several other journals of addiction and clinical psychology. Wiers is internationally known for his work on implicit cognition and addiction. He received the prestigious VIDI (2002) and VICI (2008) research grants from the Dutch National Science Foundation (N.W.O.), for research on assessing and changing implicit cognitive processes in addiction. He also received several other grants from national and international funding agencies. His 2011 Psychological Science paper on changing the approach-bias for alcohol in alcohol-dependent papers with clinical effects is in the top 1% of most cited papers of that year in psychology and psychiatry. Wiers published over 250 international papers and book chapters, and his current Hirsch-index is 45 (web of science) or 65, google scholar, see: https://scholar.google.nl/citations?user=2vKDTuoAAAAJ&hl=nl
Alcohol Use Disorders (AUDs) are typically treated with psychosocial treatments and/or medication. However, there is a third category of interventions to consider: varieties of Cognitive Training (CT). Two types of CT can be distinguished: those in which general abilities are trained (e.g. working memory training) and those in which initial motivational reactions to alcohol are targeted, so called cognitive biases (Cognitive Bias Modification, CBM). I will review the state of affairs in both. Training of general abilities takes a long time, but does show promise for a subgroup of patients. CBM has shown to increase one-year abstinence in several large clinical trials, with effect sizes similar to medication for alcohol (NNT=12). It is also becoming clear for which individuals CBM shows most promise as an add-on treatment (those with a strong cue-reactivity and/or impulsivity), and we are beginning to understand the neurocognitive mechanisms underlying training effects (e.g., reduced cue-reactivity). CT shows modest but reliable effects as add-on to regular psychosocial treatment, but does not appear to work in the absence of psychosocial treatment, nor in the absence of motivation to change (e.g. in proof-of-principle studies in students). Finally, I will sketch ways forward, such as combining training with neurostimulation.
Plenary Lecture 6
Wednesday, September 12, 13:50-14:35
Alcohol Pharmacodynamics and Neurofunctional Domains underlying Alcohol Use Disorder
- Vijay A. Ramchandani
- Section on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
Vijay Ramchandani, Ph.D., is a Clinical Investigator and Chief of the Section on Human Psychopharmacology in the intramural research program of the National Institute on Alcohol Abuse and Alcoholism, one of the National Institutes of Health, in Bethesda, MD. Dr. Ramchandani obtained his undergraduate degree in Pharmaceutical Sciences from Bombay University in India in 1990, and his Ph.D. in Pharmaceutical Sciences from Virginia Commonwealth University, Richmond, VA in 1996. From 1996 to 2002, he worked at the Alcohol Research Center at Indiana University School of Medicine, Indianapolis, IN, first as a Research Associate and then as an Assistant Scientist and Part-time Assistant Professor. In 2003, Dr. Ramchandani joined NIAAA as a Staff Scientist in the Laboratory of Clinical and Translational Studies, and started his independent research program in 2010. Dr. Ramchandani also serves as the Deputy Training Director for the NIAAA intramural program.
Dr. Ramchandani’s research is focused on characterizing the clinical pharmacology of alcohol in humans using behavioral, neuroendocrine, psychophysiological and functional imaging measures, and the relationship between alcohol response and risk factors, both genetic and environmental, for alcohol use disorders. He is also conducting studies to develop human laboratory paradigms to screen novel potential pharmacotherapies for alcohol use disorders, in terms of their ability to alter the motivation, consumption and pharmacodynamics of alcohol in high-risk drinkers.Alcohol use disorder has a tremendous negative individual and global impact, and there is an urgent need to understand its etiology as well as to advance treatment for this devastating illness. Research on the clinical pharmacology of alcohol is necessary to explain how variability in alcohol response affects the risk of developing this disorder. Furthermore, an improved understanding of the genetic, environmental, and neurobiological factors that affect alcohol response could lead to the development of novel treatments.
Dr. Ramchandani’s presentation will focus on research advances in characterization of the pharmacological effects of alcohol in humans across the neurofunctional domains of incentive salience, negative affect, and executive dysfunction that are critical to the cycle of addiction. He will include examples of his own human laboratory research that utilizes novel intravenous alcohol administration paradigms to provide a platform of highly controlled alcohol exposure, combined with a range of pharmacodynamic measures, in individuals across the spectrum of alcohol consumption and risk. These studies provide important insights into the relationship between alcohol pharmacodynamics and risk of alcohol problems, and facilitate the identification and screening of potential targets for treatment of alcohol use disorder.
Symposium
Symposium 1
Sunday, September 9, 13:30-15:00 Room A
ISBRA-APSAAR Symposium: Alcohol and the Behavioural Addictions - Part 1: Alcohol and Gambling Disorder
- Organizer / Chair:
-
Sawitri Assanangkornchai Prince of Songkla University, Thailand - Chair:
-
John B. Saunders Centre for Youth Substance Abuse Research, University of Queensland, Australia
- SY1-1
- ALCOHOL AND BEHAVIOURAL ADDICTIONS: AN OVERVIEW
- Max W. Abbott
- National Institute of Public Health and Mental Health Research, Auckland University of Technology, New Zealand
- SY1-2
- PREVALENCE AND CORRELATES OF THE BEHAVIOURAL ADDICTIONS
- Hans Jürgen Rumpf
- Department of Psychiatry and Psychotherapy, University of Lübeck, Germany
- SY1-3
- DIAGNOSIS AND CLASSIFICATION OF THE BEHAVIOURAL ADDICTIONS IN ICD-11
- John B. Saunders
- Centre for Youth Substance Abuse Research, University of Queensland, Australia
- SY1-4
- PREVALENCE OF GAMBLING AND GAMING DISORDERS IN ASIAN COUNTRIES
- Phunnapa Kittirattanapaiboon
- Department of Mental Health, Ministry of Public Health, Thailand
- DISCUSSANT:
-
John B. Saunders Centre for Youth Substance Abuse Research, University of Queensland, Australia
Symposium 2
Sunday, September 9, 15:30-17:00 Room A
ISBRA-APSAAR Symposium: Alcohol and the Behavioural Addictions - Part 2: Gaming Disorder: Diagnosis and Management
- Organizer / Chair:
-
Sawitri Assanangkornchai Prince of Songkla University, Thailand - Chair:
-
John B. Saunders Centre for Youth Substance Abuse Research, University of Queensland, Australia
- SY2-1
- TECHNIQUES FOR SCREENING AND ASSESSMENT FOR GAMING DISORDER
- Phunnapa Kittirattanapaiboon
- Department of Mental Health, Ministry of Public Health, Thailand
- SY2-2
- ASSESSMENT AND MANAGEMENT OF GAMING AND ONLINE GAMBLING DISORDER IN YOUNG ADULTS IN INDONESIA
- Kristiana Siste Kurniasanti
- Department of Psychiatry, University of Indonesia, Indonesia
- SY2-3
- MANAGEMENT OF GAMING DISORDER AND INTERNET ADDICTION IN JAPAN
- Satoko Mihara
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY2-4
- GOVERNMENT POLICIES AND PROGRAMS TO MINIMIZE THE HARM FROM GAMING DISORDER
- Sang Kyu Lee
- Psychiatry, Hallym University, Chuncheon Sacred Heart Hospital, Korea
- DISCUSSANT:
-
Karl F. Mann Central Institute of Mental Health, University of Heidelberg, Germany
Symposium 3
Sunday, September 9, 13:30-15:00 Room B-2
Risk Factors for Alcoholic Liver Disease
- Organizer / Chair:
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Helmut K. Seitz Centre of Alcohol Research University of Heidelberg, Germany - Chair:
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Manuela G. Neuman University of Toronto, Canada
- SY3-1
- GENETICS AS RISK FACTORS IN ALCOHOLIC LIVER CIRRHOSIS (ALC)
- Devanshi Seth
- Royal Prince Alfred Hospital and Centenary Institute, Australia
- SY3-2
- THE INTERPLAY OF ALCOHOL WITH DRUGS INCLUDES MULTIPLE FACETS
- Manuela Neuman
- University of Toronto, Canada
- SY3-3
- HEPATIC SINUSOIDAL PRESSURE AS PROGRESSION FACTOR FOR ALCOHOLIC LIVER DISEASE: DOES SPLEEN STIFFNESS ALLOW TO ALLOCATE THE HISTOLOGICAL SIDE OF PRESSURE ELEVATION?
- Omar Elshaarawy
- Centre of Alcohol Research University of Heidelberg, Germany
- SY3-4
- CYTOCHROME P450 (CYP2E1) AS A RISK FACTOR FOR ALCOHOLIC LIVER DISEASE (ALD)
- Helmut K. Seitz
- Centre of Alcohol Research University of Heidelberg, Germany
Symposium 4
Sunday, September 9, 15:30-17:00 Room B-2
Cellular and Extracellular Effects of Alcohol Exposure in Liver and Extrahepatic Organs
- Organizer / Chair:
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Carol A. Casey Department of Internal Medicine, University of Nebraska Medical Center and Omaha VAMC, USA - Chair:
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Terrence M. Donohue Dept. of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
- SY4-1
- ETHANOL ADMINISTRATION INCREASES POLYUBIQUITYLATION OF HEPATIC LIPID DROPLET MEMBRANE PROTEINS
- Paul G. Thomes
- University of Nebraska Medical Center, USA
- SY4-2
- TRANSCRIPTION FACTOR EB (TFEB) AND LIPOPHAGY ARE DISRUPTED BY ETHANOL FEEDING AND NORMALIZED AFTER ETHANOL WITHDRAWAL
- Terrence M. Donohue
- Dept. of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
- SY4-3
- UPREGULATED AUTOPHAGY IN SERTOLI CELLS OF ETHANOL-TREATED RATS: EVIDENCES, MECHANISMS AND IMPLICATIONS
- Nabil Eid
- Anatomy and Cell Biology Department, Division of Life Sciences, Osaka Medical College, Takatsuki, Osaka, Japan
- SY4-4
- ROLE OF SPLICING REGULATOR SLU7 IN ETHANOL-INDUCED INFLAMMATION AND LIVER INJURY
- Min You
- Department of Pharmaceutical Sciences, Northeast Ohio Medical University, USA
- SY4-5
- MIF INHIBITION PROTECTS HEPATOCYTES FROM GAO-BINGE- INDUCED INJURY INDEPENDENT OF NEUTROPHIL ACCUMULATION
- Laura Nagy
- Cleveland Clinic, USA
Symposium 5
Sunday, September 9, 13:30-15:00 Room K
Direct Alcohol Modulation of Ion Channels: Insights and Enigmas in the Post-structure Era
- Organizer / Chair:
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Rebecca J. Howard Department of Biochemistry & Biophysics, Stockholm University, Sweden - Chair:
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R Adron Harris Waggoner Center for Alcohol & Addiction Research, The University of Texas at Austin, USA
- SY5-1
- DETERMINING THE IN VIVO IMPORTANCE AND ACTION OF ETHANOL ON THE BK POTASSIUM CHANNEL
- Jon Pierce
- University of Texas at Austin, USA
- SY5-2
- DUAL ACTIVATION OF NEURONAL G PROTEIN-GATED INWARDLY RECTIFYINGPOTASSIUM (GIRK) CHANNELS BY CHOLESTEROL AND ALCOHOL
- Paul A. Slesinger
- Dept. of Neuroscience, Icahn School of Medicine at Mount Sinai, USA
- SY5-3
- CLUSTERS OF HYDROPHOBIC AMINO ACIDS IN THE MEMBRANE-ASSOCIATED DOMAINS REGULATE ION CHANNEL GATING AND FORM PUTATIVE SITES OF ALCOHOL ACTION IN THE NMDA RECEPTOR
- Robert W. Peoples
- Department of Biomedical Sciences, Marquette University, USA
- SY5-4
- ALCOHOL MODULATION VIA ALLOSTERIC TRANSMEMBRANE SITES IN PENTAMERIC LIGAND-GATED ION CHANNELS
- Rebecca J. Howard
- Department of Biochemistry & Biophysics, Stockholm University, Sweden
Symposium 6
Sunday, September 9, 15:30-17:00 Room K
Genetic and Epigenetic Signatures That Mediate Differential Alcohol Drinking and Ethanol Responses
- Organizer / Chair:
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Kristin Hamre Dept. of Anat. & Neurobiol., Univ. of Tennessee Health Science Center, USA - Chair:
-
Feng C. Zhou Indiana University School of Medicine, USA
- INTRODUCTION TO THE SYMPOSIUM:
-
Kristin Hamre Dept. of Anat. & Neurobiol., Univ. of Tennessee Health Science Center, USA
- SY6-1
- GENOMIC SIGNATURE OF ALCOHOL PREFERRING (P) AND NON-PREFERRING (NP) RATS
- Feng C. Zhou
- Indiana University School of Medicine, USA
- SY6-2
- GENETIC POLYMORPHISMS OF ADH1B AND ALDH2 AND THEIR PHENOTYPES IN JAPANESE ALCOHOLIC MEN
- Akira Yokoyama
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY6-3
- TRANSCRIPTIONAL REGULATION OF LINE-1 RETROTRANSPOSONS IN MODELS OF ALCOHOL USE DISORDER
- Igor Ponomarev
- Waggoner Center for Alcohol & Addiction Research and the College of Pharmacy, The University of Texas at Austin, USA
- SY6-4
- EPIGENETIC DYSREGULATION IN THE MPFC REGULATES ALCOHOL-ASSOCIATED BEHAVIORS
- Estelle Barbier
- Center for Social Affective Neuroscience, IKE, Linkoping University, Sweden
- DISCUSSANT:
-
Feng C. Zhou Indiana University School of Medicine, USA
Symposium 7
Sunday, September 9, 13:30-15:00 Room J
Possibilities and Challenges Using e-Health and m-Health for Addiction Treatment
- Organizer / Chair:
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Ayumi Takano Department of Psychiatric Nursing, Yokohama City University, Japan - Chair:
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Toshiaki Baba Department of Mental Health Policy, National Institute of Mental Health, Japan
- SY7-1
- HOW EFFECTIVE IS A BRIEF WEBSITE INTERVENTION WITH PERSONALIZED NORMATIVE FEEDBACK AMONG JAPANESE ADULTS WITH RISKY DRINKING? FINDINGS FROM A PILOT RCT
- Toshitaka Hamamura
- Division of Clinical Psychology, Department of Integrated Educational Sciences, The University of Tokyo, Japan
- SY7-2
- M-HEALTH INTERVENTIONS FOR GAMBLING PROBLEMS
- Ryuhei So
- Okayama Psychiatric Medical Center, Japan
- SY7-3
- SMARTPHONE-BASED SELF-MONITORING APPLICATION FOR DRUG USERS: CO-PRODUCTION WITH TARGETED USERS
- Ayumi Takano
- Department of Psychiatric Nursing, Yokohama City University, Japan
- SY7-4
- POLICY IMPLICATIONS OF EHEALTH INTERVENTIONS FOR ADDICTION
- Toshiaki Baba
- Department of Mental Health Policy, National Institute of Mental Health, Japan
Symposium 8
Sunday, September 9, 15:30-17:00 Room J
Perspectives of Occupational Therapy in Addiction
- Organizer:
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Tetsutaro Kosago National Hospital Organization Kurihama Medical and Addiction Center, Japan - Chair:
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Hitoshi Maesato National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY8-1
- ADDICTION BEHAVIOUR AS AN OCCUPATION
- Yoshitaka Sato
- Okayama Psychiatric Medical Center, Japan
- SY8-2
- OCCUPATION-FOCUSED INTERVENTION FOR RECOVERY FROM ADDICTION
- Takeshi Misawa
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY8-3
- THE COLLABORATIVE POTENTIAL OF OCCUPATIONAL THERAPY IN SUBSTANCE ADDICTION AND REHABILITATION
- Michael P. Sy
- Tokyo Metropolitan University, Japan
- SY8-4
- OCCUPATIONAL THERAPY TO MEET THE NEEDS OF ALCOHOL DEPENDENCE CLIENTS
- Tetsutaro Kosago
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 9
Sunday, September 9, 13:30-15:00 Room C-1
Gambling and Gaming Disorder
- Organizer / Chair:
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Hannu Alho Clinicum, University of Helsinki, Helsinki, Finland - Chair:
-
Susumu Higuchi National Hospital Organization Kurihama Medical and Addiction Center, Japan
- INTRODUCTION TO THE SYMPOSIUM:
-
Hannu Alho Clinicum, University of Helsinki, Helsinki, Finland
- SY9-1
- TREATING GAMBLING DISORDER WITH FAST ACTING OPIOID ANTAGONIST - NALOXONE NASAL SPRAY: A NOVEL FEASIBILITY STUDY
- Hannu Alho
- Clinicum, University of Helsinki, Helsinki, Finland
- SY9-2
- TEMPERAMENT AND CHARACTER PROFILE IN PATHOLOGICAL GAMBLING: A COMPARISON WITH ALCOHOL DEPENDENCE
- Changwoo Han
- Department of Psychiatry, Gangnam Eulji Hospital, Eulji University, Seoul, Korea
- SY9-3
- PRESENT SITUATION OF GAMBLING AND PREVALENCE OF GAMBLING DISORDERS IN JAPAN
- Sachio Matsushita
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY9-4
- CLINICAL CHARACTERISTICS OF TREATMENT SEEKING INDIVIDUALS WITH GAMBLING DISORDER IN JAPAN: A SYSTEMATIC COMPARISON OF DIAGNOSTIC CRITERIA IN ICD-11 AND DSM-5
- Takanobu Matsuzaki
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 10
Sunday, September 9, 15:30-17:00 Room C-1
Recent Findings Regarding Internet Addiction and Gaming Disorder
- Organizer:
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Hideki Nakayama National Hospital Organization Kurihama Medical and Addiction Center, Japan - Chair:
-
Dai-jin Kim Department of Psychiatry, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea
- SY10-1
- PRECISION MEDICINE IN BEHAVIOR ADDICTION
- Dai-jin Kim
- Department of Psychiatry, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea
- SY10-2
- THE ROLE OF MOTIVES IN ADDICTIVE VIDEO GAMING
- Jöel Billieux
- University of Luxembourg, Luxembourg
- SY10-3
- THE COHORT STUDY ON GAMING DISORDER: THE INTERNET USER COHORT FOR UNBIASED RECOGNITION OF GAMING DISORDER IN EARLY ADOLESCENCE (ICURE) STUDY
- Sun-jin Jo
- Dept. Preventive Medicine, College of Medicine, The Catholic University of Korea, Korea
- SY10-4
- SCREENING AND INTERVENTION NEEDS FOR INTERNET ADDICTION COMORBID WITH NEURODEVELOPMENTAL DISORDERS
- Ryuhei So
- Okayama Psychiatric Medical Center, Japan
- SY10-5
- EFFECTIVENESS OF A SCHOOL-BASED BRIEF GROUP INTERVENTION FOR THE PREVENTION OF INTERNET ADDICTION
- Hideki Nakayama
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 11
Monday, September 10, 9:50-11:20 Room A
Role and Therapeutic Potential of Oxytocin in Alcohol Addiction
- Organizer / Chair:
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Howard C. Becker Medical University of South Carolina, USA - Chair:
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Rosana Camarini University of Sao Paulo, Brazil
- SY11-1
- ROLE OF OXYTOCIN IN THE MODULATING EFFECTS OF ENVIRONMENTAL ENRICHMENT ON ALCOHOL-RELATED BEHAVIORS IN MICE
- Rosana Camarini
- University of Sao Paulo, Brazil
- SY11-2
- ROLE OF OXYTOCIN IN ALCOHOL SELF-ADMINISTRATION AND STRESS-INDUCED RELAPSE-LIKE BEHAVIOR IN MICE
- Howard C. Becker
- Medical University of South Carolina, USA
- SY11-3
- DEVELOPMENT OF SMALL MOLECULE OXYTOCIN LIGANDS FOR ALCOHOL DEPENDENCE AND DRUG ADDICTION
- Iain S. Mcgregor
- University of Sydney, Australia
- SY11-4
- THE OXYTOCIN SYSTEM IN ALCOHOLISM: CONVERGENT EVIDENCE FROM HUMANS AND RATS
- Rainer Spanagel
- Institute for Psychopharmacology, Central Institute of Mental Health Mannheim, Uniklinikum Mannheim, University of Heidelberg, Germany
- DISCUSSANT:
-
Leandro F. Vendruscolo National Institute on Drug Abuse, USA
Symposium 12
Monday, September 10, 13:00-14:30 Room A
ISBRA-JSPH Symposium: Prevention of Health Problems Due to Inadequate Alcohol Drinking -Viewpoints from Community Total Health
- Chairs:
-
Tomonori Okamura Department of Preventive Medicine and Public Health, Keio University School of Medicine, Japan -
Hideyuki Kanda Department of Environmental Medicine and Public Health, Shimane University, Japan
- SY12-1
- CANCER RISK AND ALCOHOL: GENE-ENVIRONMENT INTERACTION AMONG ASIAN
- Keitaro Matsuo
- Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Japan
- SY12-2
- ALCOHOL AND CARDIOVASCULAR DISEASE, ITS RISK FACTORS, AND OTHER HEALTH DISORDERS IN THE COMMUNITY
- Aya Higashiyama
- National Cerebral and Cardiovascular Center, Japan
- SY12-3
- ALCOHOL AND MINORS IN JAPAN
- Hideyuki Kanda
- Department of Environmental Medicine and Public Health, Shimane University, Japan
- SY12-4
- ALCOHOL-RELATED PROBLEMS IN JAPANESE PRIMARY CARE
- Hisashi Yoshimoto
- Department of Family Medicine, General Practice and Community Health, Faculty of Medicine, University of Tsukuba, Japan
- SY12-5
- PUBLIC HEALTH POLICY ON HARMFUL HEALTH HAZARDS OF ALCOHOL USE IN JAPAN: THE POPULATION STRATEGY PERSPECTIVE
- Yoneatsu Osaki
- Division of Environmental and Preventive Medicine, Department of Social Medicine, Faculty of Medicine, Tottori University, Japan
Symposium 13
Monday, September 10, 14:50-16:10 Room A
International Comparison of Measures against Alcohol-related Harm - In Reference to Japanese Basic Act - Part 1
- Organizer:
-
Aro Ino Kasumigaura Clinic, Japan - Organizer / Chair:
-
Naoyuki Hironaka Dept. Pharmacology, LSI Medience Corp., Japan - Chair:
-
Megumi Goto Psychiatry & Behavioral Sciences, Tokyo Medical and Dental University, Japan
- SY13-1
- JAPANESE BASIC ACT ON MEASURES AGAINST ALCOHOL-RELATED HARM: FORMATION, SIGNIFICANCE, AND FUTURE
- Aro Ino
- Kasumigaura Clinic, Japan
- SY13-2
- PROCESS OF FORMULATING THE BASIC LAW AND ITS SIGNIFICANCE FOR INTERNAL MEDICINE AND GENERAL PRACTICE / FAMILY MEDICINE
- Hisashi Yoshimoto
- Department of Family Medicine, General Practice and Community Health, Faculty of Medicine, University of Tsukuba, Japan
- SY13-3
- HISTORY OF PSYCHIATRIC TREATMENT FOR ALCOHOL USE DISORDER AND THE IMPACT OF BASIC ACT FOR MEASURES AGAINST ALCOHOL-RELATED HEALTH HARM IN JAPAN
- Chie Iwahara
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY13-4
- ESSENTIAL ELEMENTS OF EFFECTIVE ALCOHOL POLICIES AND THEIR IMPLEMENTATION IN THE WORLD
- Vladimir Poznyak
- Department of Mental Health and Substance Abuse, World Health Organization, Geneva, Switzerland
Symposium 14
Monday, September 10, 16:20-18:00 Room A
International Comparison of Measures against Alcohol-related Harm - In Reference to Japanese Basic Act - Part 2
- Organizer:
-
Aro Ino Kasumigaura Clinic, Japan - Organizer / Chair:
-
Naoyuki Hironaka Dept. Pharmacology, LSI Medience Corp., Japan - Chair:
-
Megumi Goto Psychiatry & Behavioral Sciences, Tokyo Medical and Dental University, Japan
- SY14-1
- THE HISTORY OF ALCOHOL RESEARCH IN THE UNITED STATES AND THE NIAAA
- Kenneth R. Warren
- National Institute on Alcohol Abuse and Alcoholism, USA
- SY14-2
- ALCOHOL POLICIES IN THE USA IN RELATION TO THE JAPANESE BASIC LAW: WHAT WE CAN LEARN FROM EACH OTHER
- Thomas F. Babor
- Department of Community Medicine, University of Connecticut School of Medicine, USA
- SY14-3
- PUBLIC HEALTH MEASURES AGAINST ALCOHOL-RELATED PROBLEMS IN THAILAND
- Sawitri Assanangkornchai
- Prince of Songkla University, Thailand
- SY14-4
- ALCOHOL POLICIES IN UK, FOCUSING ON EARLY HARM PREVENTION
- Irene Guerrini
- South London & Maudsley NHS Foundation Trust, UK
Symposium 15
Monday, September 10, 9:50-11:20 Room B-2
CIFASD Studies on the Genetics of FASD
- Organizer / Chair:
-
Edward Riley San Diego State University, USA
- SY15-1
- IDENTIFYING GENETIC MODIFIERS OF SUSCEPTIBILITY TO PRENATAL ALCOHOL EXPOSURE IN MICE
- Scott E. Parnell
- Bowles Center for Alcohol Sudies, University of North Carolina, USA
- SY15-2
- SYNERGISTIC GENE-ENVIRONMENT INTERACTIONS IN A ZEBRAFISH MODEL OF FETAL ALCOHOL SPECTRUM DISORDERS
- Johann K. Eberhart
- Department of Molecular Biosciences, University of Texas at Austin, USA
- SY15-3
- CREATION OF AN ONLINE COLLABORATIVE INITIATIVE ON FETAL ALCOHOL SPECTRUM DISORDERS (CIFASD) REGISTRY FOR THE STUDY OF THE GENETICS OF FASD
- Tatiana M. Foroud
- Department of Medical and Molecular Genetics, Indiana University School of Medicine, USA
- DISCUSSANT:
-
Edward Riley San Diego State University, USA
Symposium 16
Monday, September 10, 13:00-14:30 Room B-2
Mechanisms of Multi-organ Injury by Alcohol and HIV-1 Interactions Through the Gut-liver-brain Axis
- Organizer / Chair:
-
B. J. Song National Institute on Alcohol Abuse and Alcoholism, Laboratory of Membrane Biochemistry and Biophysics, Rockville, Maryland, USA - Chair:
-
Mohammed Akbar National Institute on Alcohol Abuse and Alcoholism, Laboratory of Membrane Biochemistry and Biophysics, Rockville, Maryland, USA
- SY16-1
- MECHANISMS OF MULTI-ORGAN INJURY BY ALCOHOL AND HIV-1 INTERACTIONS THROUGH THE GUT-LIVER-BRAIN AXIS
- Ali Keshavarzian
- Rush University Medical Center, Department of Internal Medicine, Chicago, Illinois, USA
- SY16-2
- ROLE OF CYP2E1 IN PROTEIN MODIFICATIONS AND GUT LEAKINESS, LEADING TO LIVER INFLAMMATION AND BRAIN INJURY IN HIV-1 TRANSGENIC RATS
- B.J. Song
- National Institute on Alcohol Abuse and Alcoholism, Laboratory of Membrane Biochemistry and Biophysics, Rockville, Maryland, USA
- SY16-3
- ALCOHOL AND HIV ASSOCIATED CHANGES IN THE GUT-LIVER-BRAIN AXIS: RELEVANCE TO HEPATIC INJURY AND NEUROINFLAMMATION
- Shirish Barve
- Department of Medicine, University of Louisville Medical School, Louisville, Kentucky, USA
- SY16-4
- INTERPLAY BETWEEN NEUROHIV AND BINGE EXPOSURE TO ALCOHOL
- Sulie Chang
- Institute of Neuroimmune Pharmacology and Department of Biological Sciences, Seton Hall University, South Orange, New Jersey, USA
- SY16-5
- HOW HIV-1 INFECTION AND ALCOHOL LEAD TO NEURODEGENERATION: MECHANISMS AND INTERVENTIONS
- Yuri Persidsky
- Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA
- DISCUSSANT:
-
Kendall J. Bryant National Institutes of Health, USA
Symposium 17
Monday, September 10, 14:50-16:20 Room B-2
Building a Global Alcohol Research Agenda for Reproductive and Child Health: Closing Interdisciplinary Gaps to Address the Needs of People Affected by HIV/ AIDS - Part 1
- Organizer / Chair:
-
Tatiana N. Balachova University of Oklahoma Health Sciences Center, USA - Chair:
-
Niranjan Saggurti Population Council, India
- SY17-1
- ALCOHOL USE AND ADVERSE HEALTH OUTCOMES FOR YOUNG HIV-INFECTED RUSSIAN WOMEN: ASSOCIATION BETWEEN PHOSPHATIDYLETHANOL AS A NOVEL BIOMARKER OF ALCOHOL CONSUMPTION, SEXUAL RISK, OTHER SUBSTANCE USE, AND ANTIRETROVIRAL MEDICATION ADHERENCE
- Ralph J. Diclemente
- Department of Socio-behavioral Sciences, College of Global Public Health, New York University, USA
- SY17-2
- ALCOHOL USE BY WOMEN LIVING WITH HIV (WLWH) IN UGANDA AND SOUTH AFRICA DURING PERICONCEPTION AND PREGNANCY PERIODS IS HIGH
- Lynn T. Matthews
- Massachusetts General Hospital / Harvard Medical School, USA
- SY17-3
- ALCOHOL USE AMONG HIV-INFECTED PREGNANT WOMEN AND CHILD OUTCOMES IN THE PEDIATRIC HIV AIDS COHORT STUDY (PHACS)
- Denise Jacobson
- Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA
- SY17-4
- ALCOHOL USE, PREGNANCY PLANNING, AND REPRODUCTIVE HEALTH CONCERNS IN PEOPLE LIVING WITH HIV/AIDS IN RUSSIA
- Anait Y. Marianian
- Federal State Public Scientific Institution (SC FHHRP), Russia
- DISCUSSANT:
- BUILDING A GLOBAL ALCOHOL RESEARCH AGENDA FOR REPRODUCTIVE AND CHILD HEALTH
-
Denise A. Russo National Institutes of Health, EKS National Institute of Child Health and Human Development, USA
Symposium 18
Monday, September 10, 16:30-18:00 Room B-2
Building a Global Alcohol Research Agenda for Reproductive and Child Health: Closing Interdisciplinary Gaps to Address the Needs of People Affected by HIV/ AIDS - Part 2
- Organizer / Chair:
-
Tatiana N. Balachova University of Oklahoma Health Sciences Center, USA - Chair:
-
Niranjan Saggurti Population Council, India
- SY18-1
- ROLE OF ALCOHOL ABUSE, HIV-1 INFECTION AND VAGINAL MICROBIAL DYSBIOSIS IN THE REPRODUCTIVE HEALTH OF WOMEN
- Shirish Barve
- Department of Medicine, University of Louisville, USA
- SY18-2
- ALCOHOL PHARMACOTHERAPIES TO IMPROVE ALCOHOL AND HIV TREATMENT OUTCOMES AFTER RELEASE FROM PRISON FOR WOMEN LIVING WITH HIV AND ALCOHOL USE DISORDERS IN THE UNITED STATES CRIMINAL JUSTICE SYSTEM
- Sandra A. Springer
- Department of Internal Medicine, Section of Infectious Disease, Yale School of Medicine, USA
- SY18-3
- ALCOHOL USE AND GENITAL TRACT INFECTIONS IN INDIA: LESSONS LEARNED FROM RESEARCH, COMMUNITY IMPLEMENTATION, AND BUILDING NATIONAL CAPACITY
- Niranjan Saggurti
- Population Council, India
- DISCUSSANT:
- DISCUSSION ON ALCOHOL AND HIV RESEARCH FOR REPRODUCTIVE HEALTH: CLOSING GAPS BETWEEN DISCIPLINES AND SETTING RESEARCH AGENDA
-
Kendall J. Bryant National Institutes of Health, USA
Symposium 19
Monday, September 10, 9:50-11:20 Room K
Mechanisms of Compulsive Aversion-resistant Alcohol Drinking in Rodents
- Organizer / Chair:
-
Stephen L. Boehm Department of Psychology, Indiana University - Purdue University Indianapolis, USA
- SY19-1
- AVERSION- (QUININE-) RESISTANT ALCOHOL DRINKING IN MOUSE LINES GENETICALLYSELECTED FOR HIGH AND LOW ALCOHOL PREFERENCE DRINKING
- Nicholas J. Grahame
- Department of Psychology, Indiana University - Purdue University Indianapolis, USA
- SY19-2
- NEUROBIOLOGICAL MECHANISMS UNDERLYING LOSS OF CONTROL OVER ALCOHOL USE IN RATS
- Heidi Lesscher
- Department of Animals in Science and Society, Faculty of Veterinary Medicine, Utrecht University, Netherlands
- SY19-3
- COMPULSIVE RESPONDING FOR ALCOHOL IS MORE AUTOMATIC AND MOTIVATED: INSIGHTS INTO OVERLAP OF COMPULSION AND HABIT CIRCUITRY
- Frederic W. Hopf
- University of California San Francisco, USA
- SY19-4
- COMPULSIVE ALCOHOL SEEKING IS ASSOCIATED WITH AN INABILITY TO DISENGAGE DORSOLATERAL-DOPAMINE DEPENDENT CONTROL OVER BEHAVIOUR
- Chiara Giuliano
- University of Cambridge, Department of Psychology, UK
Symposium 20
Monday, September 10, 13:00-14:30 Room K
To Be or Not to Be: Transcription and Translation Mechanisms Underlying Alcohol Use Disorders
- Organizer / Chair:
-
Dorit Ron Dept. of Neurology UCSF, USA
- SY20-1
- MTORC1 IN THE ORBITOFRONTAL CORTEX CONTROLS ALCOHOL SEEKING AND HABIT
- Dorit Ron
- Dept. of Neurology, UCSF, USA
- SY20-2
- COMMON MECHANISMS BETWEEN ETHANOL AND RAPIDLY ACTING ANTIDEPRESSANTS
- Kimberly Raab-Graham
- Wake Forest Translational Alcohol Research Center, Physiology and Pharmacology, Wake Forest School of Medicine, USA
- SY20-3
- GENOME-WIDE TRANSCRIPTIONAL CHANGES IN THE RAT HIPPOCAMPUS DURING WITHDRAWAL FROM CHRONIC ALCOHOL DRINKING IDENTIFIES ALTERED NEUROIMMUNE SIGNALING
- Amy W. Lasek
- Psychiatry, University of Illinois at Chicago, USA
- SY20-4
- MOLECULAR BASIS OF FOR CHOOSING ALCOHOL OVER A NATURAL REWARD
- Markus A. Heilig
- Center for Social and Affective Neuroscience, Sweden
- DISCUSSANT:
-
Antonio Noronha Dept. of Neurology UCSF, USA
Symposium 21
Monday, September 10, 14:50-16:20 Room K
Systems Biology for Analysis of Complex Traits Including Alcoholism (the NFPCDD Symposium)
- Organizer / Chair:
-
Boris Tabakoff Skaggs School of Pharmacy & Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, USA - Chair:
-
Paula L. Hoffman Department of Pharmacology, School of Medicine, University of Colorado Denver, USA
- SY21-1
- THE NFPCDD SYMPOSIUM ON SYSTEMS BIOLOGY FOR ANALYSIS OF COMPLEX TRAITS INCLUDING ALCOHOLISM
- Boris Tabakoff
- Skaggs School of Pharmacy & Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, USA
- SY21-2
- SYSTEMS-GENETICS TO COMPLEX DISEASES: FROM GENE NETWORKS TO DRUGGABLE TARGETS
- Enrico G. Petretto
- Duke-NUS Medical School, Singapore
- SY21-3
- USING MULTI-OMICS DATA TO DETERMINE CAUSALITY AND CONSEQUENCES FOR PATHOLOGICAL TRAITS IN ANIMALS AND HUMANS
- Mete Civelek
- Department of Biomedical Engineering, University of Virginia, USA
- SY21-4
- THE QUANTITATIVE "OMICS" ANALYSIS OF COMPLEX ALCOHOL-RELATED TRAITS IN THE HYBRID RAT DIVERSITY PANEL
- Laura M. Saba
- Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, USA
Symposium 22
Monday, September 10, 16:30-18:00 Room K
Promising Targets of Alcohol Addiction
- Organizer / Chair:
-
A Leslie Morrow Psychiatry and Pharmacology, UNC School of Medicine, USA
- SY22-1
- PRECLINICAL EVALUATION OF NEW HDAC INHIBITORS IN ANIMAL MODELS OF ALCOHOL USE DISORDERS
- Mickael Naassila
- Université de Picardie Jules Verne - INSERM UMR 1247 - GRAP; Amiens, France
- SY22-2
- TRANSGENIC RAT LINES FOR REGION SPECIFIC INTERFERENCE WITH TARGET GENE EXPRESSION: EFFECT ON ALCOHOL-SEEKING BEHAVIOR
- Wolfgang H. Sommer
(Rainer Spanagel) - Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
- SY22-3
- ALPHA-1 BLOCKADE AS PERSONALIZED TREATMENTS FOR ALCOHOL USE DISORDER
- Carolina L. Haass-Koffler
- Brown University, USA
- SY22-4
- ENDOGENOUS NEUROSTEROID ALLOPREGNANOLONE INHIBITS TOLL-LIKE-4 RECEPTOR SIGNALING TO TARGET ALCOHOL ADDICTION
- A Leslie Morrow
- Psychiatry and Pharmacology, UNC School of Medicine, USA
Symposium 23
Monday, September 10, 13:00-14:30 Room J
Chronic Alcohol Induces Plasticity in Striatal and Limbic Circuits
- Organizer / Chair:
-
Nicholas W. Gilpin LSU Health Sciences Center – New Orleans, USA
- SY23-1
- DRUG-INDUCED DYSFUNCTION IN DORSOMEDIAL STRIATUM AND IN DECISION-MAKING
- Bernard W. Balleine
- UNSW Sydney, Australia
- SY23-2
- PREFRONTAL CONTROL OVER COMPULSIVE-LIKE ETHANOL-SEEKING
- Andrew Holmes
- NIAAA, USA
- SY23-3
- ALCOHOL DEPENDENCE IMPACTS VENTRAL TEGMENTAL AREA PROJECTIONS TO CENTRAL AMYGDALA
- Elizabeth M. Avegno
- Department of Physiology, Louisiana State University Health Sciences Center, USA
- SY23-4
- DISRUPTION OF BLA-NAC CIRCUITRY LEADS TO ALTERATIONS IN ETHANOL SELF-ADMINISTRATION AND AFFECTIVE BEHAVIORS
- Sarah Ewin
- Wake Forest School of Medicine, NC, USA
Symposium 24
Monday, September 10, 14:50-16:20 Room J
Alcohol & Opioids: Intersecting Mechanisms and Treatment Opportunities for Pain Management and Addiction
- Organizer / Chair:
-
Scott Edwards LSU Health Sciences Center New Orleans, USA - Chair:
-
Marcin Wojnar Department of Psychiatry, Medical University of Warsaw, Poland
- SY24-1
- ANOTHER IMPORTANT PIECE IN A COMPLEX PUZZLE? EXPLORING SIGNIFICANCE OF PAIN IN ALCOHOL DEPENDENCE
- Marcin Wojnar
- Department of Psychiatry, Medical University of Warsaw, Poland
- SY24-2
- OPIOID USE AND PAIN: MECHANISMS OF HEAVY DRINKING RELAPSE AMONG PATIENTS WITH ALCOHOL DEPENDENCE
- Katie Witkiewitz
- University of New Mexico, USA
- SY24-3
- GLUCOCORTICOID-MEDIATED PLASTICITY UNDERLIES NEGATIVE EMOTIONAL STATES AND COMPULSIVE ALCOHOL AND OPIOID USE
- Stephanie A. Carmack
- Intramural Research Program, National Institute on Drug Abuse, USA
- SY24-4
- CENTRAL AMYGDALA CIRCUITS MEDIATE HYPERALGESIA IN ALCOHOL-DEPENDENT RATS
- Nicholas W. Gilpin
- LSU Health Sciences Center - New Orleans, USA
Symposium 25
Monday, September 10, 16:30-18:00 Room J
Alcohol and Organ Damage: Bridging the Gap Between Bench and Bedside - Part 1: Translational
- Organizer / Chair:
-
Kenichi Ikejima Department of Gastroenterology, Juntendo Univeristy Graduate School of Medicine, Japan - Chair:
-
Gavin E. Arteel Dept of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, USA
- SY25-1
- HEPATOCYTE-DERIVED EXTRACELLULAR VESICLES CONTAIN MICRORNA BARCODE TO CONTROL A UNIQUE TRANSCRIPTOME PROFILE OF ACTIVATED STELLATE CELLS IN ALCOHOLIC HEPATITIS
- Akiko Eguchi
- Department of Gastroenterology and Hepatology, Graduate School of Medicine, Mie University, Japan
- SY25-2
- MECHANISMS OF HEPATOCELLULAR FAILURE IN ALCOHOLIC HEPATITIS
- Josepmaria Argemi
- Department of Medicine, Division of Gastroenterology Hepatology and Nutrition, University of Pittsburgh, USA
- SY25-3
- MICROBIOTA AND LIVER DISEASE
- Bernd Schnabl
- Medcine, UC San Diego, USA,
- SY25-4
- PREVENTIVE EFFECTS OF L-CARNITINE ON HIGH-FAT DIETINDUCED STEATOHEPATITIS IN OBESE AND DIABETIC MICE
- Kazuyoshi Kon
- Department of Gastroenterology, Juntendo University School of Medicine, Japan
Symposium 26
Monday, September 10, 9:50-11:20 Room C-1
Binge Behaviors: Etiological Models and Underlying Psychological Factors
- Organizer / Chair:
-
Joel Billieux University of Luxembourg, Luxembourg
- SY26-1
- BINGE DRINKING - A BEHAVIORAL AND ELECTROPHYSIOLOGICAL APPROACH
- Pierre Maurage
- Psychological Science Research Institute, Université Catholique de Louvain, Belgium
- SY26-2
- BINGE-WATCHING ENGAGEMENT AS DETERMINED BY MOTIVATIONS, IMPULSIVITY AND EMOTIONAL REACTIVITY: A CLUSTER ANALYTIC APPROACH
- Maèva Flayelle
- University of Luxembourg, Luxembourg
- SY26-3
- INVESTIGATING FOOD CHOICE PROCESSES USING HAND MOVEMENTS IN BULIMIA NERVOSA AND BINGE EATING DISORDER
- Zoé Van Dyck
- University of Luxembourg, Luxembourg
Symposium 27
Monday, September 10, 14:50-16:20 Room C-1
Long-term Consequences of Heavy Drinking in Japan, Germany and U.S
- Organizer:
-
Michie N. Hesselbrock Department of Psychiatry, University of Connecticut School of Medicine, USA - Chairs:
-
Susumu Higuchi National Hospital Organization Kurihama Medical and Addiction Center, Japan Victor M. Hesselbrock Department of Psychiatry, University of Connecticut School of Medicine, USA
- SY27-1
- LIVER STIFFNESS PRIOR AND AFTER ALCOHOL DETOXIFICATION AS A NOVEL PROGNOSTIC MARKER IN HEAVY DRINKERS: FIRST DATA FROM A PROSPECTIVE COHORT
- Sebastian Mueller
- Salem Medical Center and Center for Alcohol Research, University of Heidelberg, Germany
- SY27-2
- THE EFFECT OF SMOKING ON THE TREATMENT OUTCOME OF ALCOHOLIC PATIENTS WHO RECEIVED INPATIENT CBT
- Mitsuru Kimura
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY27-3
- A 40 YEAR STUDY OF HEAVY DRINKING OUTCOMES IN HIGHLY EDUCATED MEN
- Marc A. Schuckit
- Department of Psychiatry, University of California, San Diego, USA
- SY27-4
- LONGTERM OUTCOMES IN ADULTS WITH ALCOHOL DEPENDENCE RE-ASSESSED AFTER AN AVERAGE OF 17 YEARS
- Kathleen K. Bucholz
- Psychiatry, Washington U. School of Medicine, USA
- OVERALL SUMMARY:
-
Frederic Blow University of Michigan Medical Center, USA
Symposium 28
Monday, September 10, 16:30-18:00 Room C-1
The Current Situation of Internet Gaming Disorder from the Standpoint of Young Researchers
- Organizer / Chair:
-
Yoko Nishitani Dept. of Forensic Medicine, Kumamoto University, Japan - Chair:
-
Tomohiro Shirasaka Department of Psychiatry, Teine Keijinkai Hospital, Japan
- SY28-1
- INTERNET GAMING DISORDER IN CHILDREN AND ADOLESCENTS: AN UPDATED LITERATURE REVIEW
- Nagisa Sugaya
- Unit of Public Health and Preventive Medicine, School of Medicine, Yokohama City University, Japan
- SY28-2
- A REPORT ON A TREATMENT PROGRAM FOR INTERNET GAMING DISORDER AMONG SOUTH KOREAN YOUTH
- Jangrae Kim
- Department of Addiction Psychiatry, National Center for Mental Health, an affiliate of the Ministry of Health and Welfare, Korea
- SY28-3
- SPOTLIGHTS ON INTERNET GAMING DISORDER AMONG UNIVERSITY STUDENTS IN EGYPT
- Hussien Elkholy
- Neurology and Psychiatry Department, Faculty of Medicine, Ain Shams University, Egypt
- SY28-4
- GAMING DEVICE USAGE PATTERNS AND INTERNET GAMING DISORDER AMONG YOUNG ADULTS IN SOUTH KOREA
- Soo-hyun Paik
- Addiction Center, Keyo Hospital, Korea
- SY28-5
- CLINICAL CHARACTERISTICS OF SOCIAL WITHDRAWAL (HIKIKOMORI) AND PROBLEMATIC INTERNET USE IN JAPAN
- Tomohiro Shirasaka
- Department of Psychiatry, Teine Keijinkai Hospital, Japan
Symposium 29
Tuesday, September 11, 9:55-11:25 Room A
Transgenic Animal and Pharmacological Studies of Alcohol Metabolites, from Peripheral Organs to Brain
- Organizer:
-
Bin Gao National Institute on Alcohol Abuse and Alcoholism, NIH, USA - Chairs:
-
Katherine Jung Division of Metabolism and Health Effects, National Institute on Alcohol Abuse and Alcoholism, USA Li Zhang National Institute on Alcohol Abuse and Alcoholism, NIH, USA
- INTRODUCTION TO THE SYMPOSIUM:
-
Katherine Jung Division of Metabolism and Health Effects, National Institute on Alcohol Abuse and Alcoholism, USA
- SY29-1
- GENETIC DELETION OF ALDH2 EXACERBATES ALCOHOL AND CCL4-INDUCED LIVER INFLAMMATION AND FIBROSIS
- Hyo-jung Kwon
- College of Veterinary Medicine, Chung-Nam National University, Korea
- SY29-2
- ALDH2 AND OBESITY CARDIOMYOPATHY
- Jun Ren
- University of Wyoming, USA
- SY29-3
- ALDH2 SUPPRESSES CIRRHOSIS/FIBROSIS AND ALCOHOL-INDUCED HEPATOCELLULAR CARCINOMA VIA THE INHIBITION OF ACETALDEHYDE-DERIVED DNA DAMAGE AND MULTIPLE ONCOGENIC SIGNALING PATHWAYS
- Bin Gao
- NIAAA, NIH, USA
- SY29-4
- PERINATAL AND INFANTILE DEVELOPMENT: CRITICAL STAGES FOR THE ANALYSIS OF ACETALDEHYDE´S MOTIVATIONAL PROPERTIES IN HETEROGENOUS RATS
- Juan C. Molina
- Instituto de Investigacion Medica Mercedes y Martin Ferreyra, Argentina
- SY29-5
- CELL-TYPE SPECIFIC DISTRIBUTION OF BRAIN ALDH2 AND ITS CONTRIBUTION TO CANNABIS AND ETHANOL-INDUCED SYNERGISTIC EFFECTS ON PSYCHOMOTOR IMPAIRMENT
- Li Zhang
- National Institute on Alcohol Abuse and Alcoholism, NIH, USA
- DISCUSSANT:
-
Helmut K. Seitz Centre of Alcohol Research University of Heidelberg, Germany
Symposium 30
Tuesday, September 11, 14:55-16:25 Room A
Novel Findings from Bench to Bedside - Glutamate Hypothesis for Addictive Disorder
Co-sponsored by Eisai Co., Ltd.
- Chair:
-
Hidehiko Takahashi Department of Psychiatry, Kyoto University Graduate School of Medicine, Japan
- SY30-1
- THE ROLE OF GLUTAMATE ACTIVITY AT AMPA RECEPTORS IN ADDICTIVE DISORDER
- Takuya Takahashi
- Department of Physiology, Yokohama City University School of Medicine, Japan
- SY30-2
- ANTI-CRAVING DRUG AND THE STRUCTURE OF CRAVING
- Hisatsugu Miyata
- Department of Psychiatry, Jikei University School Medicine, Japan
Symposium 31
Tuesday, September 11, 16:30-18:00 Room A
Common and Different Mechanisms Underlying Dependence on Alcohol and Other Addictive Substances
- Organizer / Chair:
-
Kazutaka Ikeda Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, Japan - Chair:
-
Michie N. Hesselbrock Department of Psychiatry, University of Connecticut School of Medicine, USA
- SY31-1
- CAN WE UNTANGLE ALCOHOL AND COMORBID SUBSTANCE DEPENDENCE?
- Victor M. Hesselbrock
- Dept. of Psychiatry, University of Connecticut School of Medicine, USA
- SY31-2
- TELOMERE SHORTENING IN PATIENTS WITH ALCOHOL OR OTHER ADDICTIVE SUBSTANCES DEPENDENCE
- Ming-chyi Huang
- Department of Psychiatry, Taipei City Psychiatric Center, Taipei City Hospital, Taiwan
- SY31-3
- PREFERENCE FOR ALCOHOL WITHOUT DEPENDENCE RISK: COMPARISON WITH OTHER ADDICTIVE SUBSTANCES
- Hisatsugu Miyata
- Department of Psychiatry, Jikei University School of Medicine, Japan
- SY31-4
- GIRK CHANNELS AS COMMON EFFECTORS IN SOME PATHWAYS OF ALCOHOL AND OTHER ADDICTIVE SUBSTANCES
- Kazutaka Ikeda
- Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, Japan
Symposium 32
Tuesday, September 11, 9:55-11:25 Room B-1
Diverse Roles of Non-protein-coding RNAs: Alcohol-mediated Neuroinflammation, Regulation of Neural Stem Cell Renewal, and Epigenetic Regulation in Early Onset and Chronic Alcohol Use Disorders
- Organizer / Chair:
-
R. Dayne Mayfield Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, USA
- SY32-1
- CHRONIC ALCOHOL-INDUCED MICRORNA-155 CONTRIBUTES TO NEUROINFLAMMATION IN A TLR4- DEPENDENT MANNER IN MICE
- Gyongyi Szabo
- University of Massachusetts Medical School, USA
- SY32-2
- A NOVEL PSEUDOGENE-ENCODED LONG NONCODING RNA MEDIATES FETAL ALCOHOL EFFECTS
- Rajesh C. Miranda
- Dept. of Neuroscience, Texas A&M University College of Medicine, USA
- SY32-3
- BDNF-AS IS A NOVEL LNCRNA THAT IS AN EPIGENETIC REGULATOR IN EARLY ONSET ALCOHOL USE DISORDERS
- John P. Bohnsack
- Department of Psychiatry, Alcohol Research Center on Epigenetics, University of Illinois at Chicago, USA
- SY32-4
- NOVEL LONG NON-CODING RNAS INVOLVED IN ALCOHOL USE DISORDER
- Sean P. Farris
- The University of Texas at Austin, USA
- DISCUSSANT:
-
Jillian J. Kril Sydney Medical School, University of Sydney, Australia
Symposium 33
Tuesday, September 11, 14:55-16:25 Room B-1
Emerging Role of Epigenetic Processes in the Development of Alcohol Use Disorders
- Organizer / Chair:
-
Subhash C. Pandey Center for Alcohol Research In Epigenetics, Dept. of Psychiatry, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago IL 60612, USA - Chair:
-
Antonio Noronha NIH-NIAAA, Bethesda MD, USA
- INTRODUCTION TO THE SYMPOSIUM:
-
Antonio Noronha Dept. of Neurology UCSF, USA
- SY33-1
- LONG-LASTING EPIGENETIC MARK OF ALCOHOL HAS A DEVELOPMENTAL WINDOW
- Dipak K. Sarkar
- Endocrine Program, Rutgers University, USA
- SY33-2
- EPIGENETIC REPROGRAMMING REGULATES ENHANCER RNA AND ADULT PSYCHOPATHOLOGY AFTER ADOLESCENT ALCOHOL EXPOSURE
- Subhash C. Pandey
- Center for Alcohol Research In Epigenetics, Dept. of Psychiatry, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago IL 60612, USA
- SY33-3
- METHYLATION PROFILES DURING ACUTE ALCOHOL WITHDRAWAL IN A CLINICAL SAMPLE
- Stephanie H. Witt
- Department of Genetic Epidemiology in Psychiatry, CIMH Mannheim/Heidelberg University, Mannheim, Germany
- SY33-4
- ROLE OF HDAC IN BINGE DRINKING LIKE ETHANOL EXPOSURE-INDUCED ALTERATIONS IN ANXIETY, MEMORY AND SYNAPTIC PLASTICITY DURING ADOLESCENCE IN RATS
- Mickael Naassila
- Université de Picardie Jules Verne - UMR INSERM U1247 - GRAP, Amiens, France
- DISCUSSANT:
-
Dipak K. Sarkar Endocrine Program, Rutgers University, USA
Symposium 34
Tuesday, September 11, 16:30-18:00 Room B-1
A Role for the Insular Cortex in Alcohol Use Disorders?
- Organizer / Chair:
-
Angelo Bifone Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Italy
- SY34-1
- INTRODUCTION TO THE POTENTIAL ROLE OF THE INSULAR CORTEX IN AUD
- Frederic W. Hopf
- University of California San Francisco, USA
- SY34-2
- RESTING STATE FUNCTIONAL CONNECTIVITY OF THE INSULAR CORTEX IN RECENTLY DETOXIFIED ALCOHOLICS
- Angelo Bifone
- Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Italy
- SY34-3
- REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (RTMS) OF THE INSULA FOR TREATMENT OF ALCOHOL ADDICTION
- Irene Perini
- Centre for Social and Affective Neuroscience, Sweden
- SY34-4
- CHEMOGENETIC INTERROGATION OF THE ROLE OF INSULA IN ALCOHOL CONSUMPTION
- Petri Hyytiä
- Department of Pharmacology, University of Helsinki, Finland
- SY34-5
- ALTERED INSULAR CORTEX CONNECTIVITY IN ALCOHOL POST-DEPENDENT RATS AND NORMALIZATION BY A D3 RECEPTOR SELECTIVE ANTAGONIST
- Giulia Scuppa
- Center for Neuroscience and Cognitive Systems, Istituto Italiano di Tecnologia, Rovereto, Italy
- DISCUSSANT:
-
Frederic W. Hopf University of California San Francisco, USA
Symposium 35
Tuesday, September 11, 9:55-11:25 Room B-2
Dysregulation of Protein Homeostasis (Proteostasis): Novel Mechanism in Alcohol Use Disorders and Organ Injury
- Organizer / Chair:
-
Pranoti Mandrekar Dept of Medicine, University of Massachusetts Medical School, USA - Chair:
-
Andras Orosz Div of Metabolism and Health Effects, NIAAA, NIH, USA
- SY35-1
- CELL-TO-CELL VARIABLE MOLECULAR RESPONSES FOR MAINTENANCE OF PROTEOSTASIS EPIGENETICALLY PROGRAM LIFE-LONG PATHOLOGICAL CONDITIONS IN FASD
- Kazue Hashimoto-Torii
- Children's National Medical Center, USA
- SY35-2
- INHIBITING NLRP3 INFLAMMASOME AND IL-1BETA IN ALCOHOLIC LIVER DISEASE VIA THERAPEUTIC TARGETING OF THE PROTEOSTASIS CHAPERONE
- Pranoti Mandrekar
- Dept. of Medicine, University of Massachusetts Medical School, USA
- SY35-3
- COLLAGEN-SPECIFIC MOLECULAR CHAPERONE HSP47 WOULD BE A THERAPEUTIC TARGET FOR FIBROTIC DISEASES
- Shinya Ito
- Institute for Protein Dynamics, Kyoto Sangyo University, Japan
- SY35-4
- ETHANOL-INDUCED DISORGANIZATION OF GOLGI APPARATUS AND ALTERED PROTEIN TRAFFICKING: ROLE OF DEFECTIVE RAB3D FUNCTION
- Carol A. Casey
- Department of Internal Medicine, University of Nebraska Medical Center and Omaha VAMC, USA
Symposium 36
Tuesday, September 11, 14:55-16:25 Room B-2
Alcohol and Organ Damage: Bridging the Gap Between Bench and Bedside - Part 2: Bench
- Organizer / Chair:
-
Kenichi Ikejima Department of Gastroenterology, Juntendo Univeristy Graduate School of Medicine, Japan - Chair:
-
Gavin E. Arteel Dept. of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, USA
- SY36-1
- THE ROLE OF ENDOPLASMIC RETICULUM STRESS ON ALCOHOLIC LIVER INJURY IN A MURINE MODEL OF CHRONIC-BINGE ETHANOL FEEDING
- Maiko Suzuki
- Juntendo Univeristy Graduate School of Medicine, Japan
- SY36-2
- LYSOSOMAL BIOGENESIS AND ALCOHOLIC PANCREATITIS
- Wen-xing Ding
- Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, USA
- SY36-3
- MACROPHAGE INHIBITORY FACTOR (MIF) ATTENUATES HEPATIC STEATOSIS, BUT PROMOTES HEPATIC CARCINOGENESIS
- Norio Horiguchi
- Gunma University of Medicine, Internal Medicine of Gastroenterology and Hepatology, Japan
- SY36-4
- TRANSITIONAL CHANGES TO THE MATRISOME AND ALCOHOLIC LIVER DISEASE, MORE THAN COLLAGEN AND FIBROSIS
- Gavin E. Arteel
- Dept. of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, USA
Symposium 37
Tuesday, September 11, 9:55-11:25 Room K
Young Investigator's Symposium in Asia 1
- Organizer / Chair:
-
Sung-gon Kim Psychiatry, Pusan National University, Korea
- SY37-1
- RATE OF BLACKOUT AND ITS NEGATIVE CONSEQUENCES IN UNIVERSITY STUDENTS
- Kyeong-Mi Kang
- Busan Community Addiction Management Center, Korea
- SY37-2
- PREDICTIVE FACTORS FOR TREATMENT FAILURE IN REDUCING ALCOHOLIC CONSUMPTION BY CASE MANAGEMENT FOR ALCOHOLICS LIVING IN PERMANENT RENTAL APARTMENTS
- Myung-hee Song
- Psychiatric Nurse / Department of Busan Cmmunity Addiction Management Center, Pusan National University Hospital, Korea
- SY37-3
- CHANGES IN THE DRINKING BEHAVIOR OF KOREAN WOMEN DURING THE PREVIOUS 20 YEARS
- Bi A Seo
- Pusan National University Yangsan Hospital, Korea
- SY37-4
- SENSIBLE AND NATURAL ALCOHOLISM PREVENTION PROGRAM FOR YOU (SNAPPY), A SUITE OF WEB-BASED SCREENING AND BRIEF INTERVENTION TOOLS FOR EXCESSIVE ALCOHOL CONSUMPTION
- Takashi Sunami
- Saga-ken Medical Centre Koseikan, Japan
Symposium 38
Tuesday, September 11, 14:55-16:25 Room K
The Current Situation and Treatment Systems for Drug Addiction in Asia
- Organizer / Chair:
-
Tomohiro Shirasak Department of Psychiatry, Teine Keijinkai Hospital, Japan - Chair:
-
Toshikazu Saito Psychiatry Institute, Hokujinkai Medical Corporation, Japan
- SY38-1
- DRUG ABUSE IN MALAYSIA
- Anne Yee
- University Malaya, Malaysia
- SY38-2
- TREATMENT SYSTEM OF DRUG ADDICTION IN TAIWAN: MOVING FORWARD ON A WANDERING JOURNEY
- Chia Chun Hung
- Bali Psychiatric Center, Ministry of Health and Welfare, Taiwan
- SY38-3
- TREATMENT SYSTEM FOR DRUG ADDICTION IN INDONESIA: CHALLENGING SYSTEM FOR DEVELOPING COUNTRY
- Kristiana Siste Kurniasanti
- Department of Psychiatry, University of Indonesia, Indonesia
- SY38-4
- CONSIDERATIONS ON THE PRESENT TREATMENT SYSTEMS AND ISSUES OF DRUG ADDICTION IN JAPAN
- Moritoshi Kido
- Osaka University of Commerce, Japan
Symposium 39
Tuesday, September 11, 16:30-18:00 Room K
Leaning from the Differences Regarding the Relationship Between Social Structures and Substances Use
- Organizer / Chair:
-
Masuo Tanaka Koryo Hosipital, Japan - Chair:
-
Tetsuji Cho Department of Psychiatry, Mental Care Center, Prefecture of Mie, Japan
- SY39-1
- CHANGES IN TREATMENT FOR ALCOHOL USE DISORDER IN JAPAN
- Tetsuji Cho
- Department of Psychiatry, Mental Care Center, Mie, Japan
- SY39-2
- DIFFERENT CHARACTERISTICS OF AUD BETWEEN THE US AND JAPAN
- Hiroshi Sakuma
- Saigata Medical Center, Japan
- SY39-3
- CURRENT SITUATION ON SUBSTANCE USE DISORDERS IN BOSNIA AND HERZEGOVINA
- Visnja Banjac
- Clinic of Psychiatry, University Clinical Center of the Republic of Srpska, Bosnia and Herzegovina
- SY39-4
- IRELAND'S ALCOHOL PROBLEM: A PUBLIC HEALTH ISSUE
- Leo Yoshida
- National Suicide Research Foundation, Ireland
Symposium 40
Tuesday, September 11, 9:55-11:25 Room C-1
Binge Drinking: From Risk to Consequences
- Organizer / Chair:
-
John Crabbe Department of Behavioral Neuroscience, Oregon Health & Science University, USA
- SY40-1
- BEHAVIORAL FACTORS PREDICTING THE RISK OR RESILIENCE TO CONSUME ALCOHOL AND LOSE CONTROL OVER ALCOHOL SEEKING IN RATS
- Heidi Lesscher
- Department of Animals in Science and Society, Faculty of Veterinary Medicine, Utrecht University, Netherlands
- SY40-2
- A ROLE FOR PHOSPHODIESTERASE TYPE 4 (PDE4) IN BINGE-LIKE DRINKING
- Angela R. Ozburn
- Oregon Health & Science University, USA
- SY40-3
- MATERNAL ALCOHOL BINGE DRINKING INDUCES MOLECULAR ALTERATIONS IN THE BRAIN AND BEHAVIORAL DYSFUNCTIONS IN OFFSPRING MICE
- Lídia Cantacorps
- Neurobiology of Behavior Research Group (GReNeC-NeuroBio), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Spain
- SY40-4
- ASSOCIATION BETWEEN EXCESSIVE ALCOHOL USE AND ALCOHOL-RELATED INJURIES - A MULTICENTER CROSS SECTIONAL STUDY OF COLLEGE STUDENTS IN JAPAN
- Kyoko Kawaida
- Nursing Faculty of National Defense Medical College, Japan
Symposium 41
Tuesday, September 11, 14:55-16:25 Room C-1
Novel Technologies and Integrated Approaches for Obtaining and Using Real-time Alcohol Consumption Data Collected in Naturalistic Environments
- Organizer / Chair:
-
Susan E. Luczak University of Southern California, USA - Chair:
-
Vijay A. Ramchandani National Institute on Alcohol Abuse and Alcoholism, USA
- INTRODUCTION TO THE SYMPOSIUM:
-
Katherine Jung Division of Metabolism and Health Effects, National Institute on Alcohol Abuse and Alcoholism, USA
- SY41-1
- A NOVEL POPULATION-BASED MODEL APPROACH TO ESTIMATING BREATH ALCOHOL CONCENTRATION (BRAC) FROM TRANSDERMAL ALCOHOL CONCENTRATION (TAC) BIOSENSOR DATA
- Susan E. Luczak
- University of Southern California, USA
- SY41-2
- USING EMA AND SENSOR DATA TO UNDERSTAND THE RELATIONSHIPS BETWEEN DRINKING AND EMOTIONAL STATES AMONG PERSONS LIVING WITH HIV (PLWH)
- Yan Wang
- University of Florida, USA
- SY41-3
- ALTERNATE REPRESENTATIONS OF SUBJECTIVE EFFECTS: AN ECOLOGICAL STUDY OF SIMULTANEOUS ALCOHOL AND MARIJUANA USE
- Kristina M. Jackson
- Brown University, USA
- SY41-4
- TESTING THE EFFICACY OF THE MOBILE INTERVENTION FOR DRINKING IN YOUNG PEOPLE (MIDY): AN ECOLOGICAL MOMENTARY INTERVENTION TO REDUCE YOUNG ADULTS ALCOHOL USE IN THE EVENT
- Cassandra J. Wright
- Burnet Institute, Australia
- DISCUSSANT:
-
Kenneth J. Sher Department of Psychological Sciences, University of Missouri, USA
Symposium 42
Tuesday, September 11, 16:30-18:00 Room C-1
The Fact and Issue of Alcohol Use Among Asian Adolescences - For the Purpose of Future Collaboration on Youth Risk Behaviour Monitoring
- Organizer / Chair:
-
Yoneatsu Osaki Division of Environmental and Preventive Medicine, Department of Social Medicine, Faculty of Medicine, Tottori University, Japan
- SY42-1
- ALCOHOL AND DRUGS ABUSE AMONG ADOLESCENT IN INDONESIA
- Kristiana Siste Kurniasanti
- Department of Psychiatry, University of Indonesia, Indonesia
- SY42-2
- ALCOHOL USE AMONG ADOLESCENTS IN KOREA
- Sungwon Roh
- Department of Psychiatry, Hanyang University College of Medicine, Korea
- SY42-3
- PREVALENCE, CHARACTERISTICS, AND FACTORS ASSOCIATED WITH ALCOHOL USE AMONG ADOLESCENTS IN THAILAND: A REVIEW OF PUBLISHED DATA
- Wanlop Atsariyasing
- Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
- SY42-4
- THE FACTS AND ISSUES OF ALCOHOL USE AMONG ADOLESCENTS AND YOUTH IN JAPAN
- Aya Kinjo
- Division of Environmental and Preventive Medicine, Department of Social Medicine, Faculty of Medicine, Tottori University, Japan
Symposium 43
Tuesday, September 11, 9:55-11:25 Room C-2
Update of Alcohol Dependence/Alcohol Use Disorder and Their Treatment in US, EU, and Japan
Co-sponsored by Otsuka Pharmaceutical Co., Ltd.
- Chair:
-
Toshikazu Saito Psychiatry Institute, Hokujinkai Medical Corporation, Japan
- SY43-1
- CURRENT SITUATION AND FUTURE TASKS FOR THE TREATMENT OF ALCOHOL DEPENDENCE IN JAPAN
- Susumu Higuchi
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY43-2
- TRENDS IN THE TREATMENT OF ALCOHOL DEPENDENCE IN THE EU
- Jonathan Chick
- Edinburgh Napier University and Castle Craig Hospital, UK
- SY43-3
- THE CURRENT STATUS OF ALCOHOL USE DISORDER AND ITS TREATMENT IN THE U.S.
- Robert M. Swift
- Brown University Center for Alcohol and Addiction Studies, USA
Symposium 44
Tuesday, September 11, 14:55-16:25 Room C-2
Alcohol Misuse Effects on Brain Structure from Adolescence to Senescence: In Vivo MRI, Indices for Identifying At-risk Youth, Postmortem Brain-Bank Material for Validating in Vivo Findings and Enabling Genetic Investigations
- Organizer / Chair:
-
Edith V. Sullivan Psychiatry, Stanford University School of Medicine, USA - Chair:
-
Adolf Pfefferbaum SRI International, Menlo Park, California, USA
- SY44-1
- LONGITUDINAL STUDIES OF ALCOHOLISM-RELATED BRAIN STRUCTURAL CHANGES FROM ADOLESCENCE TO SENESCENCE
- Adolf Pfefferbaum
- SRI International, Menlo Park, California, USA
- SY44-2
- LEVEL OF RESPONSE TO ALCOHOL MEASURED ON THE SELF-RATING OF THE EFFECTS OF ALCOHOL QUESTIONNAIRE IN KOREAN MEDICAL STUDENTS
- Alfreda Stadlin
- College of Medicine, Ajman University, United Arab Emirates
- SY44-3
- USING HUMAN POST-MORTEM BRAIN TISSUE TO ADVANCE THE UNDERSTANDING OF ALCOHOL-RELATED BRAIN DAMAGE
- Jillian J. Kril
- Sydney Medical School, University of Sydney, Australia
- SY44-4
- COMBINING GWAS AND TRANSCRIPTOME DATA TO DEFINE GENES AND PATHWAYS IN ALCOHOLISM
- R. Dayne Mayfield
- Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, USA
Symposium 45
Tuesday, September 11, 16:30-18:00 Room C-2
New Perspectives in the Pharmacotherapy of Alcohol Dependence
- Organizer / Chair:
-
Karl F. Mann Central Institute of Mental Health, University of Heidelberg, Germany - Chair:
-
Susumu Higuchi National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY45-1
- A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, 3-PARALLEL-GROUP COMPARISON TRIAL TO INVESTIGATE THE EFFECT OF NALMEFENE ON ALCOHOL CONSUMPTION REDUCTION IN PATIENTS WITH ALCOHOL DEPENDENCE IN JAPAN
- Susumu Higuchi
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY45-2
- CAN WE LIMIT TENDENCY OF DOCTORS TO INAPPROPRIATE DIAGNOSIS AND PHARMACOTHERAPY IN ALCOHOL AND SUBSTANCE MISUSING PATIENTS?
- Jonathan Chick
- Edinburgh Napier University and Castle Craig Hospital, UK
- SY45-3
- REDUCED DRINKING FOR ALCOHOL DEPENDENT PATIENTS, WHAT IS THE EVIDENCE IN PHARMACOTHERAPY TRIALS?
- Karl F. Mann
- Central Institute of Mental Health, University of Heidelberg, Germany
- SY45-4
- ALTERNATIVE ENDPOINTS IN ALCOHOL CLINICAL TRIALS: THE WORLD HEALTH ORGANIZATION DRINKING RISK LEVELS
- Katie Witkiewitz
- University of New Mexico, USA
- DISCUSSANT:
-
Stephanie S. O'Malley Yale School of Medicine, USA
Symposium 46
Wednesday, September 12, 9:55-11:25 Room A
Understanding Neural Circuits Underlying Natural and Ethanol Reward
- Organizer / Chair:
-
Igor Ponomarev Waggoner Center for Alcohol & Addiction Research and the College of Pharmacy, The University of Texas at Austin, USA
- SY46-1
- MECHANISMS ENCODING SEXUAL AND ETHANOL REWARD WITHIN THE DROSOPHILA NERVOUS SYSTEM
- Galit Shohat-Ophir
- The Faculty of Life Sciences and The Multidisciplinary Brain Research Center, Bar Ilan University, Israel
- SY46-2
- CIRCUITS AND MOLECULES DRIVING CUE-INDUCED ALCOHOL PREFERENCE
- Emily Petruccelli
- Department of Neuroscience, Brown University, USA
- SY46-3
- LASTING EFFECTS OF INCREASING NUCLEUS ACCUMBENS ACTIVITY ON BINGE-LIKE ALCOHOL DRINKING AND THE TRANSCRIPTOME
- Angela R. Ozburn
- Oregon Health & Science University, USA
- SY46-4
- THE EFFECTS OF THE PDE4 INHIBITOR APREMILAST ON CELLULAR PHYSIOLOGY AND ETHANOL DRINKING
- Regina A. Mangieri
- The University of Texas at Austin, USA
Symposium 47
Wednesday, September 12, 14:55-16:25 Room A
A New Era of Alcoholism Research for Unveiling Neural, Cognitive, and Genetic Dysfunctions; From Basic to Bedside
- Organizer / Chair:
-
Shigenobu Toda Department of Psychiatry, Showa University School of Medicine, Japan - Chair:
-
Ming Chyi Huang Department of Psychiatry, Taipei City Psychiatric Center, Taipei City Hospital, Taiwan
- SY47-1
- HOW IS A HABIT DEVELOPED OR UNDEVELOPED?: IMPLICATIONS FOR A CRITICAL ROLE OF ATTENTION DURING A GOAL-DIRECTED PROCESS OF OPERANT LEARNING IN RATS
- Shigenobu Toda
- Department of Psychiatry, Showa University School of Medicine, Japan
- SY47-2
- HOW SOCIAL DEPRIVATION DIFFERENTIALLY AFFECTS ALCOHOL INTAKE BEHAVIOR AMONG MALE AND FEMALE MICE?
- Yuki Moriya
- Biological Psychiatry, Tohoku University Graduate School of Medicine, Sendai, Japan
- SY47-3
- IDENTIFICATION OF GENETIC POLYMORPHISMS ASSOCIATED WITH HUMAN SENSITIVITY TO ADDICTIVE SUBSTANCES AND ITS CLINICAL APPLICATION
- Daisuke Nishizawa
- Department of Psychiatry and Behavioral Science (Addictive Substance Project), Tokyo Metropolitan Institute of Medical Science, Japan
- SY47-4
- A REPORT OF THE FUNCTIONAL MRI STUDY WITH SEVERE ALCOHOL USE DISORDER (AUD) PATIENTS
- Shou Fukushima
- Department of Neuropsychiatry, Nagasaki University, Nagasaki, Japan
Symposium 48
Wednesday, September 12, 16:30-18:00 Room A
WHO-ISBRA Symposium: Advances in Alcohol Research and Alcohol Policy Developments
- Organizer:
-
Susumu Higuchi National Hospital Organization Kurihama Medical and Addiction Center, Japan - Chair:
-
Vladimir Poznyak Management of Substance Abuse, World Health Organization, Switzerland
- SY48-1
- EFFECTIVE POLICY MEASURES TO REDUCE ALCOHOL-RELATED HARM: AN UPDATE OF THE BOOK, "ALCOHOL: NO ORDINARY COMMODITY"
- Thomas F. Babor
- Department of Community Medicine, University of Connecticut School of Medicine, USA
- SY48-2
- MOVING BEYOND THE GREAT EXCEPTION: THE GLOBAL CHALLENGE OF REGULATING ALCOHOL
- Robin Room
- Centre for Alcohol Policy Research, La Trobe University, Melbourne, Australia
- SY48-3
- MEASURING AND PREVENTING ALCOHOL USE AND RELATED HARM AMONG YOUNG PEOPLE IN ASIAN COUNTRIES: A THEMATIC REVIEW
- Xiao J. Xiang
- Second Xiangya Hospital of Central South University, China
- SY48-4
- THE CHANGES IN ALCOHOL CONSUMPTION EPIDEMIOLOGY AND MARKETING, AND ITS IMPLICATION IN ALCOHOL POLICY IN KOREA
- Hae Kook Lee
- Department of Psychiatry, The Catholic University of Korea, Seoul, Korea
Symposium 49
Wednesday, September 12, 9:55-11:25 Room B-1
Genetic Studies on the Development and Consequences of Alcohol Use Disorders
- Organizer / Chair:
-
Sachio Matsushita National Hospital Organization Kurihama Medical and Addiction Center, Japan - Chair:
-
Akitoyo Hishimoto Department of Psychiatry, Kobe University Graduate School of Medicine, Japan
- SY49-1
- THE ROLE OF SYSTEM xCT IN ADDICTION
- Wei-Ling Chen
- Chiayi & Wanqiao Branch, Taichung Veterans General Hospital, Taiwan
- SY49-2
- ALCOHOL-RELATED POLYMORPHISMS AND RISK FOR SUICIDE IN THE JAPANESE POPULATION
- Ikuo Otsuka
- Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
- SY49-3
- PERCEIVED RESPONSE TO ALCOHOL AS A PHENOTYPE FOR RISK OF ALCOHOL RELATED PROBLEMS IN YOUNG JAPANESE ADULTS
- Sachio Matsushita
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY49-4
- ABERRANT TELOMERES IN ALCOHOL DEPENDENCE, MOOD DISORDER AND SUICIDE
- Naruhisa Yamaki
- Department of Psychiatry, Kobe University Graduate School of Medicine, Japan
Symposium 50
Wednesday, September 12, 14:55-16:25 Room B-1
The Role of Glycinergic Mechanisms for Ethanol's Mechanism of Action and for Controlling Alcohol Intake
- Organizer / Chair:
-
Bo Soderpalm Institute of Neuroscience and Physiology, University of Gothenburg, Sweden - Chair:
-
Luis Aguayo Department of Physiology, University of Concepcion, Chile
- SY50-1
- ROLE OF ALPHA1 AND ALPHA2 SUBUNITS IN ETHANOL MEDIATED POTENTIATION OF GLYCINE RECEPTORS IN NUCLEUS ACCUMBENS
- Luis Aguayo
- Department of Physiology, University of Concepcion, Chile
- SY50-2
- ROLE OF TAURINE FOR ETHANOL´S INTERACTION WITH GLYCINE RECEPTORS CONTROLLING DOPAMINE IN THE NUCLEUS ACCUMBENS
- Mia Ericson
- Institute of Neuroscience and Physiology, University of Gothenburg, Sweden
- SY50-3
- CHRONIC INTERMITTENT VOLUNTARY ALCOHOL ADMINISTRATION ELEVATES GLYCINE SIGNALS IN THE LATERAL HABENULA OF RATS
- Jiang H. Ye
- Anesthesiology, Rutgers, the State University of New Jersey, USA
- SY50-4
- A HUMAN LABORATORY TRIAL ASSESSING HIGH-DOSE GLYCINE FOR REDUCING ALCOHOL CRAVING IN ALCOHOL DEPENDENT SUBJECTS
- Helga Lidö
- Institute of Neuroscience and Physiology, University of Gothenburg, Sweden
Symposium 51
Wednesday, September 12, 16:30-18:00 Room B-1
HIV and Alcohol Co-morbidities: Pathogenesis and Treatment
- Organizers / Chairs:
-
Natalia A. Osna University of Nebraska Medical Center, USA -
Patricia E. Molina Comprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, USA
- SY51-1
- ALCOHOL-SIV/HIV-ART INTERACTIONS & METABOLIC COMORBIDITY PATHWAYS
- Patricia E. Molina
- Comprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, USA
- SY51-2
- ALCOHOL POTENTIATES HIV-INDUCED EXTRACELLULAR VESICLES (EV) RELEASE: CONTRIBUTION TO LIVER INFLAMMATION AND FIBROSIS
- Natalia A. Osna
- University of Nebraska Medical Center, USA
- SY51-3
- ALCOHOL AND HIV-INFECTION INDUCED EPIGENETIC HISTONE MODIFICATIONS IMPAIR CD4+ T LYMPHOCYTE GENE EXPRESSION: RELEVANCE TO HIV-1 PATHOGENESIS
- Shirish Barve
- Department of Medicine, University of Louisville, USA
- SY51-4
- NEUROPATHOLOGICAL MECHANISMS OF ALCOHOL, SIV, AND ANTIRETROVIRAL THERAPY: ENHANCED SUSCEPTIBILITY OF THE FRONTAL CORTEX IN RHESUS MACAQUES
- Scott Edwards
- Alcohol & Drug Abuse Center of Excellence, Neuroscience Center of Excellence, LSU Health Sciences Center, New Orleans, USA
- SY51-5
- TRIAL OF ZINC SUPPLEMENTATION TO IMPROVE MARKERS OF MORTALITY AND HIV DISEASE PROGRESSION IN HIV-POSITIVE DRINKERS IN RUSSIA
- Elena Blokhina
- Pavlov First State Medical University, Russia
Symposium 52
Wednesday, September 12, 9:55-11:25 Room B-2
Translational Research on the Neurodevelopmental Effects of Prenatal Alcohol Exposure and Treatment Strategies for Fetal Alcohol Spectrum Disorders
- Organizer / Chair:
-
Jeffrey R. Wozniak University of Minnesota, USA - Chair:
-
Jennifer D. Thomas Center for Behavioral Teratology, San Diego State University, USA
- SY52-1
- EVALUATING THE EFFECTIVENESS OF MINOCYCLINE TREATMENT FOLLOWING PRENATAL ALCOHOL EXPOSURE: IMPACTS ON BEHAVIOUR AND IMMUNE FUNCTION
- Tamara S. Bodnar
- The University of British Columbia, Canada
- SY52-2
- THYROID FUNCTION IN PREGNANT WOMEN WITH MODERATE TO SEVERE ALCOHOL CONSUMPTION IS RELATED TO INFANT DEVELOPMENTAL OUTCOMES
- Kirsty A. Donald
- University of Cape Town, South Africa
- SY52-3
- CHOLINE ALTERS HIPPOCAMPAL DEVELOPMENT: IMPLICATIONS FOR THE TREATMENT OF FETAL ALCOHOL SPECTRUM DISORDERS
- Jennifer Thomas
- Center for Behavioral Teratology, San Diego State University, USA
- SY52-4
- CHOLINE AS A NEURODEVELOPMENTAL INTERVENTION FOR CHILDREN WITH FETAL ALCOHOL SPECTRUM DISORDERS
- Jeffrey R. Wozniak
- University of Minnesota, USA
Symposium 53
Wednesday, September 12, 14:55-16:25 Room B-2
Alcohol-induced Organ Damages
- Organizer / Chair:
-
Toshikazu Saito Psychiatry Institute, Hokujinkai Medical Corporation, Japan - Chair:
-
Sebastian Mueller Salem Medical Center and Center for Alcohol Research, University of Heidelberg, Germany
- SY53-1
- DYSFUNCTION OF AUTOPHAGY IS INVOLVED IN THE PROGRESSION OF ALCOHOLIC AND NON-ALCOHOLIC FATTY LIVER DISEASES
- Shunhei Yamashina
- Department of Gastroenterology, Juntendo University School of Medicine, Japan
- SY53-2
- ALCOHOL-RELATED IRON OVERLOAD: ROLE OF NOX4 IN HEPATIC IRON SIGNALING
- Ines Silva
- Center for Alcohol Research, University of Heidelberg and Salem Medical Center, Heidelberg, Germany
- SY53-3
- MASKED HEMOLYSIS AS IMPORTANT FACTOR OF IRON OVERLOAD IN ALD
- Vanessa Rausch
- Center for Alcohol Research, University Hospital Heidelberg and Salem Medical Center, Germany
- SY53-4
- ALCOHOLIC LIVER INJURY: CLINICAL ASPECTS IN RELATION TO PATHOGENESIS AND HEPATOCARCINOGENESIS
- Makiko Taniai
- Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan
Symposium 54
Wednesday, September 12, 16:30-18:00 Room B-2
Alcohol Use Disorders and Comorbid Conditions
- Organizer / Chair:
-
Ismene L. Petrakis Department of Psychiatry, Yale University School of Medicine, USA
- SY54-1
- ALCOHOL USE DISORDER AND CO-MORBID SMOKING: EARLY PREDICTORS OF END OF TREATMENT SMOKING AND DRINKING IN A TRIAL OF VARENICLINE TARTRATE
- Stephanie S. O'Malley
- Yale School of Medicine, USA
- SY54-2
- SUPPORTIVE TEXT MESSAGES FOR PATIENTS WITH ALCOHOL USE DISORDER AND COMORBID DEPRESSION. SIX MONTH RANDOMISED CONTROLLED TRIAL WITH AFTERCARE
- Conor K. Farren
- Department of Psychiatry, Trinity College Dublin, Ireland
- SY54-3
- PHARMACOLOGIC TREATMENT OF AUD AND COMORBID POSTTRAUMATIC STRESS DISORDER (PTSD): IMPACT OF PTSD ON TREATMENT OUTCOMES
- Ismene L. Petrakis
- Department of Psychiatry, Yale University School of Medicine, USA
- SY54-4
- IMPACT OF PSYCHIATRIC COMORBIDITY ON TREATMENT OUTCOME FOR INPATIENTS WITH ALCOHOL DEPENDENCE
- Yosuke Yumoto
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 55
Wednesday, September 12, 9:55-11:25 Room K
The Current Situation and Treatment Systems for Alcoholics in Pacific Countries
- Organizer / Chair:
-
Tomohiro Shirasaka Department of Psychiatry, TeineKeijinkai Hospital, Japan - Chair:
-
Hisatsugu Miyata Department of Psychiatry, Jikei University School of Medicine, Japan
- SY55-1
- THE CURRENT SITUATION AND TREATMENT SYSTEMS FOR ALCOHOLISM IN KOREA
- Euihyeon Na
- Addiction Treatment Center, Department of Psychiatry, Maeumsarang Hospital, Korea
- SY55-2
- SURVEY OF THE RELATIONSHIP BETWEEN ALCOHOL-RELATED COGNITIVE DYSFUNCTION AND CEREBRAL BLOOD FLOW
- Tomohiro Shirasaka
- Department of Psychiatry, Teine Keijinkai Hospital, Japan
- SY55-3
- DETECTION OF ALCOHOL USE DISORDER IN A GENERAL HOSPITAL
- Woraphat Ratta-Apha
- Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
- SY55-4
- THE USE OF GABAERGIC SUBSTANCES IN BUPRENORPHINE MAINTENANCE TREATMENT
- Tae Woo Park
- Department of Psychiatry, Boston University School of Medicine, USA
Symposium 56
Wednesday, September 12, 14:55-16:25 Room K
Young Investigator's Symposium in Asia 2
- Organizer:
-
Sung-gon Kim Psychiatry, Pusan National University, Korea - Chair:
-
Woo-young Jung Department of Psychiatry, Pusan National University Yangsan Hospital, Korea
- SY56-1
- THE CHARACTERISTICS OF ALCOHOLICS VISITING A COMMUNITY COUNSELING CENTER
- Eun Jeong Min
- Psychiatry, Pusan National University Yangsan Hospital, Korea
- SY56-2
- A STUDY ON SELECTION FACTORS OF HOSPITALS BEFORE HOSPITALIZATION OF KOREAN ALCOHOL-DEPENDENT PATIENTS
- Na-yeong Byeon
- Psychiatry Social Worker, Busan Community Addiction Management Center, Pusan National University Hospital, Korea
- SY56-3
- EFFECTS OF EXPERIENCING THE TEMPLE STAY PROGRAM ON DRINKING BEHAVIOR IN KOREAN ALCOHOL-DEPENDENT PATIENTS
- Jung-soo Lee
- S.W / Department of Busan Community Addiction Management Center, Pusan National University Hospital, Korea
- SY56-4
- SURVEY FINDINGS ON THE CIRCUMSTANCES AND ATTITUDES OF CHUGGING AMONG JAPANESE YOUNG ADULTS
- Hiroaki Itoh
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 57
Wednesday, September 12, 16:30-18:00 Room K
Emerging Issues on Addiction in Indonesia
- Organizer / Chair:
-
Kristiana Siste Kurniasanti Department of Psychiatry, University of Indonesia, Indonesia
- SY57-1
- PRESCRIPTION DRUGS ABUSE IN INDONESIA: NEW PHENOMENON, HOW TO HANDLE?
- Daniella Satyasari
- Residents in Psychiatry Department, University of Indonesia/Cipto Mangunkusumo Hospital, Indonesia
- SY57-2
- SMARTPHONE ADDICTION AMONG YOUNG PEOPLE: IS IT REAL IN INDONESIA?
- Enjeline Hanafi
- Department of Psychiatry, University of Indonesia, Indonesia
- SY57-3
- NATIONAL TREATMENT PROGRAM TO MANAGE EMERGING ISSUES ON ADDICTION
- Iman Firmansyah
- National Narcotic Board, Indonesia
- SY57-4
- ADDICTION MODULE FOR UNDERGRADUATE STUDENTS SCHOOL OF MEDICINE ATMA JAYA CATHOLIC UNIVERSITY OF INDONESIA
- Eva Suryani Lie
- Department Mental Health and Behavior, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Indonesia
Symposium 58
Wednesday, September 12, 9:55-11:25 Room C-1
How Should We Promote a Strategy for Healthy Drinking?
- Organizer / Chair:
-
Koshi Nakamura Department of Public Health, Hokkaido University Faculty of Medicine, Japan - Chair:
-
Kohji Takada Department of Psychology, Teikyo University, Japan
- SY58-1
- ALCOHOL USE IN ASIA AND PUBLIC HEALTH APPROACHES FOR REDUCING ALCOHOL-RELATED HARM IN JAPAN
- Aya Kinjo
- Division of Environmental and Preventive Medicine, Department of Social Medicine, Faculty of Medicine, Tottori University, Japan
- SY58-2
- THE USE OF ALCOHOL MIXED WITH CAFFEINATED BEVERAGES IN TAIWANESE MANUAL WORKERS
- Wan-ju Cheng
- Department of Psychiatry, China Medical University Hospital, Taiwan
- SY58-3
- SAFETY/HEALTHY DRINKING PROGRAM: HOW DOES IT WORK IN THE THAI CONTEXT?
- Wachiraporn Arunothong
- Department of Psychiatry, Lampang Regional Hospital, Lampang, Thailand
- SY58-4
- ESTABLISHING ALCOHOL CESSATION PROGRAM IN MALAYSIA SETTING: INTEGRATING PSYCHODYNAMIC CONSTRUCTS IN THE MODULE
- Hazli Zakaria
- The National University of Malaysia, Malaysia
Symposium 59
Wednesday, September 12, 14:55-16:25 Room C-1
Disasters and Addictive Behaviors
- Organizer / Chair:
-
Sachio Matsushita National Hospital Organization Kurihama Medical and Addiction Center, Japan - Chair:
-
Kristiana Siste Kurniasanti Department of Psychiatry, University of Indonesia, Indonesia
- SY59-1
- CANNABIS ABUSE IN TEEN SURVIVORS WHO LOST SIGNIFICANT FIGURES IN EARTHQUAKE AND TSUNAMI1
- Syahrial B. Marwan Iskandar
- University of Indonesia, Indonesia
- SY59-2
- ALCOHOL-RELATED PROBLEMS IN FUKUSHIMA: MULTIDIMENSIONAL EFFECTS CAUSED BY THE NUCLEAR DISASTER
- Masaharu Maeda1
- Department of Disaster Psychiatry, Fukushima Medical University, Japan,
- SY59-3
- ALCOHOL USE, MENTAL HEALTH AND PHYSICAL HEALTH STATUS IN BEREAVED FAMILIES OF THE SEWOL FERRY DISASTER IN KOREA
- Ji-ae Yun
- Department of Psychiatry, Eulji University Hospital, Korea
- SY59-4
- THE IMPACT OF THE GREAT EAST JAPAN EARTHQUAKE ON ALCOHOL AND HYPNOTIC USE AND GAMBLING BEHAVIORS IN DISASTER-STRICKEN AREAS
- Sachio Matsushita
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 60
Wednesday, September 12, 9:55-11:25 Room C-2
The e:Med Consortium Uses a Systems Medicine Approach to Predict for Alcohol Use Disorders Trajectories, Treatment Responses and Mode of Action for New Anti-craving Drugs
- Organizer / Chair:
-
Rainer Spanagel Central Institute for Mental Health, Germany - Chair:
-
Hamid R. Noori Max Planck Institute for Biological Cybernetics, Germany
- SY60-1
- DEFINING INDIVIDUAL RISK PROFILES IN ADOLESCENTS THAT ARE PREDICTIVE OF ALCOHOL USE DISORDERS LATER IN LIFE
- Sylvane Desrivières
- King's College London, UK
- SY60-2
- DEFINING RISK AND RESILIENCE FACTORS FOR THE COURSE OF ALCOHOL USE DISORDERS
- Katrin Charlet
- National Institute on Alcohol Abuse and Alcoholism (NIAAA) / National Institutes of Health (NIH), USA
- SY60-3
- PREDICTING DISEASE TRAJECTORIES AND TREATMENT RESPONSE IN RATS WITH BASELINE ACTIVITY AND DRINKING DATA
- Rainer Spanagel
- Central Institute for Mental Health, Germany
- SY60-4
- PREDICTING NEUROCHEMICAL RESPONSES AND MECHANISMS OF PUTATIVE ANTI-CRAVING DRUGS
- Hamid Noori
- Max Planck Institute for Biological Cybernetics, Germany
Symposium 61
Wednesday, September 12, 14:55-16:25 Room C-2
ISBRA Young Investigator Award Symposium
- Chair:
-
Marissa Roberto, Ph.D. Member of the ISBRA Board of Directors and Education Committee
- Oral Presentations:
- YIA-1
- CRITICAL ROLE FOR THE ANTERIOR INSULAR CORTEX IN THE PROPENSITY TO RELAPSE FOLLOWING PUNISHMENT-IMPOSED ABSTINENCE TO ALCOHOL SEEKING
- Erin J. Campbell
- The Florey Institute of Neuroscience and Mental Health, Australia
- YIA-2
- CIRCUITS AND MOLECULES DRIVING CUE-INDUCED ALCOHOL PREFERENCE
- Emily Petruccelli
- Department of Neuroscience, Brown University, USA
- YIA-3
- RISK FACTORS FOR LONG-TERM PRESCRIPTION OF BENZODIAZEPINE: COHORT STUDY USING A LARGE HEALTH INSURANCE CLAIM DATABASE IN JAPAN
- Ayumi Takano
- Department of Psychiatric Nursing, Yokohama City University, Japan
- Poster Presentations:
- YIA-4
- NICOTINE INCREASES ALCOHOL SELF-ADMINISTRATION VIA MU OPIOID RECEPTOR ACTIVITY IN THE VENTRAL TEGMENTAL AREA
- Esi Domi
- Center for Social and Affective Neuroscience, IKE, Linkoping University, Linkoping, 581 83, Sweden
- YIA-5
- EARLY POSTNATAL ETHANOL EXPOSURE AFFECTS MIDLINE THALAMUS AND BEHAVIORS DEPENDENT ON PREFRONTAL-THALAMO-HIPPOCAMPAL CIRCUIT IN ADULT RAT
- Zachary H. Gursky
- Department of Psychological & Brain Sciences, University of Delaware, USA
Symposium 62
Thursday, September 13, 9:00-10:30 Room A
Ventral Hippocampus Circuits and Alcoholismrelated Behavior
- Organizer / Chair:
-
Jacqueline M. Barker Department of Pharmacology and Physiology, Drexel University, USA - Chair:
-
William C. Griffin Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, USA
- SY62-1
- THE ROLE OF THE VENTRAL HIPPOCAMPUS IN APPROACH-AVOIDANCE CONFLICT RESOLUTION - RELEVANCE TO ADDICTION
- Rutsuko Ito
- Department of Psychology, University of Toronto Scarborough, Canada
- SY62-2
- THE ROLE OF THE VENTRAL HIPPOCAMPAL TO ACCUMBENS PATHWAY ON ETHANOL DRINKING IN ETHANOL DEPENDENT AND NON-DEPENDENT MICE
- William C. Griffin
- Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, USA
- SY62-3
- REGULATION OF BEHAVIORAL FLEXIBILITY BY VENTRAL HIPPOCAMPUS PROJECTIONS
- Jacqueline M. Barker
- Department of Pharmacology and Physiology, Drexel University, USA
- SY62-4
- THE VENTRAL HIPPOCAMPUS MAY REPRESENT A NEXUS FOR MALADAPTIVE SYNAPTIC ALTERATIONS ASSOCIATED WITH ALCOHOL USE DISORDER AND COMORBID ANXIETY DISORDERS
- Jeff L. Weiner
- Department of Physiology and Pharmacology, Wake Forest School of Medicine, USA
Symposium 63
Thursday, September 13, 10:50-12:20 Room A
Modulation of Reward Mechanisms by Alcohol
- Organizer / Chair:
-
Esa R. Korpi Department of Pharmacology, University of Helsinki, Finland - Chair:
-
Elisabet Jerlhag Holm Department of Pharmacology, University of Gothenburg, Sweden
- SY63-1
- EXPLOITING BRAIN DOPAMINE (DA) SYSTEMS FOR DEVELOPMENT OF NEW TREATMENT MODALITIES FOR ALCOHOL USE DISORDER (AUD)
- Bo Söderpalm
- University of Gothenburg, Sweden
- SY63-2
- MODULATION OF VTA NEUROPLASTICITY AND REWARDING BEHAVIORS OF ETHANOL BY GABA-B RECEPTOR PAMS
- Esa R. Korpi
- Department of Pharmacology, University of Helsinki, Finland
- SY63-3
- ETHANOL ACUTE EFFECTS ON THE STRIATAL GABAERGIC PROJECTIONS TO THE SUBSTANTIA NIGRA PARS RETICULADA AND THE GLOBUS PALLIDUS
- Karina P. Abrahao
- NIAAA/NIH, USA
- SY63-4
- GUT-BRAIN PEPTIDES AND ALCOHOL USE DISRORDERS: ROLE OF REWARD MECHANISMS
- Elisabet Jerlhag
- Department of Pharmacology, University of Gothenburg, Sweden
Symposium 64
Thursday, September 13, 9:00-10:30 Room B-1
Novel Mechanisms of Ethanol-induced Damage to the Developing Brain
- Organizer / Chair:
-
Carlos F. Valenzuela Department of Neurosciences/ University of New Mexico Health Sciences Center, Albuquerque, NM, USA - Chair:
-
Consuelo Guerri Research Center Principe Felipe, Cell Pathology Laboratory, Valencia, Spain
- SY64-1
- ALCOHOL-INDUCED MICROCEPHALY INVOLVES A REDUCTION IN RETINOIC ACID SIGNALING IN THE HEAD-INDUCING PRECHORDAL MESENDODERM
- Abraham Fainsod
- Dept. of Developmental Biology and Cancer Research, Faculty of Medicine, Hebrew University of Jerusalem, Israel
- SY64-2
- ROLE OF THE TLR4 IMMUNE RESPONSE IN ALCOHOLINDUCED BRAIN DYSFUNCTIONS IN A MODEL OF FETAL ALCOHOL SPECTRUM DISORDERS (FASD)
- Maria Pascual
- Department of Molecular and Cellular Pathology of Alcohol, Principe Felipe Research Center, Valencia, Spain
- SY64-3
- EXPOSURE OF MICE TO ETHANOL DURING THE THIRD TRIMESTER-EQUIVALENT PERIOD DAMAGES HIPPOCAMPAL INTERNEURONS
- Carlos F. Valenzuela
- Department of Neurosciences, University of New Mexico Health Sciences Center, Albuquerque, NM, USA
- SY64-4
- PRENATAL ALCOHOL EXPOSURE ALTERS WHITE MATTER MICROSTRUCTURE IN NEONATES AND 2 YEAR OLDS
- Kirsten A. Donald
- University of Cape Town, South Africa
- DISCUSSANT:
-
Edward Riley San Diego State University, USA
Symposium 65
Thursday, September 13, 10:50-12:20 Room B-1
Adolescent Alcohol Abuse: Risks, Mechanisms of Pathology and Consequences
- Organizer / Chair:
-
Fulton T. Crews Director of The Bowles Center for Alcohol Studies, UNC - Chapel Hill, USA
- SY65-1
- ADOLESCENT INTERMITTENT ALCOHOL EXPOSURE ENHANCES SENSITIVITY TO FUTURE STRESS EVENTS THAT PROMOTE ABNORMAL FEAR-RELATED BEHAVIOR IN ADULTHOOD
- Lawrence J. Chandler
- Department of Neuroscience, Medical University of South Carolina, USA
- SY65-2
- ALCOHOL BINGEING IN YOUNG ADULTS IS ASSOCIATED WITH ALTERED BRAIN REGIONAL FMRI RESPONSES TO ATTENTIONAL, DECISION MAKING AND EMOTIONAL CHALLENGES; PREDISPOSING FACTORS
- Theodora Duka
- School of Psychology, University of Sussex, UK
- SY65-3
- BINGE-LIKE ETHANOL TREATMENT IN ADOLESCENCE IMPAIRS AUTOPHAGY AND HINDERS SYNAPTIC MATURATION: ROLE OF THE NEUROIMMUNE ACTIVATION
- Consuelo Guerri
- Research Center Principe Felipe, Cell Pathology Laboratory, Valencia, Spain
- SY65-4
- NEUROIMMUNE ACTIVATION BY ADOLESCENT ALCOHOL EXPOSURE AND IN HUMAN ALCOHOLIC BRAIN
- Fulton T. Crews
- Director of The Bowles Center for Alcohol Studies, UNC – Chapel Hill, USA
- DISCUSSANT:
-
Dai Stephens Department of Psychology, University of Sussex, UK
Symposium 66
Thursday, September 13, 9:00-10:30 Room B-2
Epigenetic Mechanisms of Alcohol Toxicity
- Organizer:
-
A Leslie Morrow Bowles Center for Alcohol Studies, UNC School of Medicine, USA - Chair:
-
Rajesh Miranda Texas A&M University, USA
- SY66-1
- MICRORNA BIOMARKERS AND MEDIATORS OF PRENATAL ALCOHOL EFFECTS
- Rajesh C. Miranda
- Texas A&M University, USA
- SY66-2
- HDACS MEDIATE ETHANOL MECHANISMS OF ETHANOL DEPENDENCE INVOLVING GABA-A RECEPTOR FUNCTION AND EXPRESSION
- A Leslie Morrow
- Bowles Center for Alcohol Studies, UNC School of Medicine, USA
- SY66-3
- MOLECULAR BIOMARKERS OF GENE EXPRESSION AND EPIGENETIC MIRNAS IN AUD
- Nicolas Ramoz
- INSERM U894, Center of Psychiatry and Neuroscience, France
- SY66-4
- DIFFERENTIAL METHYLATION OF ALDH2 GENE PROMOTER IN PATIENTS WITH AUD
- Hansi Pathak
- Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Germany
Symposium 67
Thursday, September 13, 10:50-12:20 Room B-2
Mechanisms, Biomarkers and Targets for Therapy in Alcohol-associated Liver Injury: From Genetics to Nutrition
- Organizer / Chair:
-
Irina A. Kirpich Department of Medicine, University of Louisville, USA - Chair:
-
Kusum Kharbanda University of Nebraska Medical Center; VA Medical Center, USA
- SY67-1
- PLASMA RESOLVIN D1 LEVELS ARE REDUCED IN ALCOHOLIC HEPATITIS: A POSSIBLE MECHANISM OF AND POTENTIAL THERAPY FOR ALCOHOLIC LIVER DISEASE
- Irina Kirpich
- Department of Medicine, University of Louisville, USA
- SY67-2
- DEFECTIVE METHYLATION REACTIONS PROMOTE THE PATHOGENESIS OF ALCOHOLIC LIVER INJURY: PREVENTION BY BETAINE ADMINISTRATION
- Kusum K. Kharbanda
- University of Nebraska Medical Center, USA
- SY67-3
- PANETH CELL DYSFUNCTION MEDIATES ALCOHOL-INDUCED DYSBIOSIS AND HEPATITIS IN MICE: ROLE OF ZINC DEFICIENCY
- Zhanxiang Zhou
- Center for Translational Biomedical Research, University of North Carolina at Greensboro, Kannapolis, NC 28081, USA
- SY67-4
- RELEVANCE OF GENETICS IN ALCOHOLIC LIVER DISEASE (ALD)
- Devanshi Seth
- Royal Prince Alfred Hospital and Centenary Institute, Australia
- SY67-5
- BIOMARKERS FOR ALCOHOLIC HEPATITIS: IMPLICATIONS FOR DIAGNOSIS AND THERAPY
- Shirish Barve
- University of Louisville, USA
Symposium 68
Thursday, September 13, 9:00-10:30 Room K
Recent Studies on Alcohol Use Disorders in Japan and Korea
- Organizer:
-
Sung-gon Kim Psychiatry, Pusan National University, Korea - Chair:
-
Kyeseong Lee Incheon ChamSarang Hospital, Korea
- SY68-1
- CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE IV GENE POLYMORPHISMS IN KOREAN ALCOHOL-DEPENDENT PATIENTS
- Woo-young Jung
- Department of Psychiatry, Pusan National University Yangsan Hospital, Korea
- SY68-2
- PREDICTING FACTORS OF LONG-TERM FOLLOW-UP IN TREATING ALCOHOLICS WITH NALTREXONE OR ACAMPROSATE IN KOREA
- Sung Young Huh
- Department of Psychiatry, Pusan National University Yangsan Hospital, Korea
- SY68-3
- DIFFERENCE OF EXECUTIVE DYSFUNCTION BETWEEN ALCOHOL DEPENDENCE &SCHIZOPHRENIA IN COMPARISON WITH TRAUMATIC BRAIN INJURY AND NORMALCONTROL SUBJECT
- Kyeseong Lee
- Incheon ChamSarang Hospital, Korea
- SY68-4
- THE EFFECTS OF BRIEF INTERVENTION AT A WORK PLACE
- Hitoshi Maesato
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 69
Thursday, September 13, 10:50-12:20 Room K
Recent Clinical Studies on Genetic Polymorphisms of Ethanol-metabolizing Enzymes in Japan and Korea
- Organizer:
-
Sung-gon Kim Psychiatry, Pusan National University, Korea - Chair:
-
Sachio Matsushita National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY69-1
- AN ASSOCIATION STUDY ABOUT ALCOHOL METABOLISM AND ITS EFFECTS ON COGNITION AND SUBJECTIVE ALCOHOL EFFECT IN POPULATIONS WITH DIFFERENT ALDH2 GENOTYPES
- Sung-gon Kim
- Psychiatry, Pusan National University, Korea
- SY69-2
- SLOW-METABOLIZING ADH1B AND INACTIVE HETEROZYGOUS ALDH2 INCREASE VULNERABILITY TO FATTY LIVER AND DECREASE VULNERABILITY TO CIRRHOSIS IN JAPANESE MEN WITH ALCOHOL DEPENDENCE
- Akira Yokoyama
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY69-3
- IDENTIFICATION OF RISK FACTORS FOR ALCOHOL DEPENDENCE USING THE AIA MODEL: COMORBID PSYCHIATRIC AND PERSONALITY DISORDERS
- Mitsuru Itoh
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
- SY69-4
- INFLUENCE OF GENETIC VARIATION IN ETHANOL-METABOLIZING ENZYMES ON ALCOHOL USE AND DIAGNOSIS OF ALCOHOL DEPENDENCE AMONG JAPANESE MALE ALCOHOLICS
- Tomoko Yonemoto
- National Hospital Organization Kurihama Medical and Addiction Center, Japan
Symposium 70
Thursday, September 13, 10:50-12:20 Room C-1
Methamphetamine Epidemic in the Philippines and Countermeasures to Overcome Problems
- Organizer / Chair:
-
Takayuki Harada University of Tsukuba, Japan - Chair:
-
Ivanhoe Escartin Department of Health, Philippines
- SY70-1
- PROJECT FOR INTRODUCING EVIDENCE-BASED RELAPSE PREVENTION PROGRAM TO DRUG DEPENDENCE TREATMENT AND REHABILITATION CENTERS IN THE PHILIPPINES
- Ivanhoe Escartin
- Department of Health, Philippines
- SY70-2
- DETERMINANTS OF RELAPSE RISKS AMONG DRUG USERS PARTICIPATING IN TREATMENT PROGRAMS AT RESIDENTIAL FACILITIES AND COMMUNITIES IN THE PHILIPPINES
- Shogo Kanamori
- Japan International Cooperation Agency, Japan
- SY70-3
- ASSESSING THE SEVERITY OF DEPENDENCE AMONG DRUG USERS PARTICIPATING IN TREATMENT PROGRAMS AT RESIDENTIAL FACILITIES AND COMMUNITIES IN THE PHILIPPINES
- Alfonso Villaroman
- Department of Health, Philippines
- SY70-4
- RECOVERY CLINICS AND RECOVERY HOMES: RAPID DEVELOPMENT OF A PUBLIC-SECTOR, COMMUNITY-BASED, FULLY VOLUNTARY MEDICAL TREATMENT MODEL OF ADDICTION CARE IN THE PHILIPPINES
- Peter Banys
- European Union - EPOS, Philippines
Symposium 71
Thursday, September 13, 9:00-10:30 Room C-2
Allosteric Modulator Drugs As Potential Treatments for Alcohol Use Disorders
- Organizer / Chair:
-
Robert M. Swift Brown University Center for Alcohol and Addiction Studies, USA - Chair:
-
Carolina Haass-Koffler Brown University, USA
- SY71-1
- DESIGN, SYNTHESIS AND CHARACTERIZATION OF SMALL MOLECULE GROUP II METABOTROPIC GLUTAMATE RECEPTOR ALLOSTERIC MODULATORS
- Nicholas Cosford
- Sanford Burnham Prebys Medical Discovery Institute, USA
- SY71-2
- DEVELOPMENT OF CORTICOTROPIN RELEASING FACTOR BINDING PROTEIN ALLOSTERIC MODULATORS
- Carolina L. Haass-Koffler
- Brown University, USA
- SY71-3
- LONGITUDINAL NEUROIMAGING OF MGLU5 DURING ALCOHOL ABSTINENCE
- Ansel Hillmer
- Dept. of Psychiatry, Yale University, USA
- SY71-4
- EFFECT OF THE MGLUR5 MODULATOR GET 73 ON ALCOHOL PHARMACOKINETICS AND PHARMACODYNAMICS AND ALCOHOL CRAVING IN A HUMAN LABORATORY MODEL
- Robert M. Swift
- Brown University Center for Alcohol and Addiction Studies, USA
Symposium 72
Thursday, September 13, 10:50-12:20 Room C-2
New Insights on the Neurobiology of Alcoholism: A Step Forward for Medication Development
- Organizer / Chair:
-
Roberto Ciccocioppo University of Camerino, Italy - Chair:
-
Koji Teshima Mitsubishi Tanabe Pharma Corporation, Japan
- SY72-1
- ALCOHOL DEPENDENCE AND WITHDRAWAL DYSREGULATE THE AMYGDALAR GABAERGIC SYNAPSES
- Marisa Roberto
- Department of Neuroscience, The Scripps Research Institute, USA
- SY72-2
- STIMULI CONDITIONED TO ALCOHOL CONSUMPTION DURING WITHDRAWAL PRODUCE COMPULSIVE-LIKE BEHAVIOR IN TESTS OF ALCOHOL SEEKING AS MEASURED BY RESISTANCE TO PUNISHMENT AND TOLERANCE OF INCREASED WORKLOAD
- Friedbert Weiss
- The Scripps Research Institute, USA
- SY72-3
- NOCICEPTIN RECEPTOR ANTAGONISM DECREASES ALCOHOL DRINKING AND SEEKING IN MALE AND FEMALE MARCHIGIAN SARDINIAN ALCOHOL-PREFERRING (MSP) RATS
- Roberto Ciccocioppo
- University of Camerino, Italy
- SY72-4
- ML375 A NOVEL NEGATIVE ALLOSTERIC MODULATOR (NAM) OF (M5) MUSCARINIC RECEPTOR (MACHR) ATTENUATES ALCOHOL DRINKING AND SEEKING IN GENETICALLY SELECTED IP RATS THROUGH MODULATION OF DORSOLATERAL STRIATUM M5 RECEPTORS
- Andrew J. Lawrence
- Florey Institute of Neuroscience & Mental Health, Australia
ISBRA-WHO Workshop
ISBRA-WHO Workshop 1
Sunday, September 9, 13:30-15:00 Room B-1
Defining and Diagnosing Disorders Due to Substance Use and Addictive Behaviours: Focus on ICD-11 and Its Comparisons With ICD-10 and Dsm-5
- Facilitator:
-
Vladimir Poznyak Management of Substance Abuse,World Health Organization, Switzerland
The workshop will focus on innovations in nomenclature and classification of disorders due to alcohol and other substance use and addictive behaviours in the 11th revision of International Classification of Diseases (ICD-11) release by the World Health Organization (WHO) in June 2018. The introductory presentation made by WHO staff (Dr V. Poznyak) will be followed by critical assessments of classification of mental and behavioural disorders (Dr W. Kosmowski, Poland) and disorders due to addictive behaviours (Dr K. Sisite, Indonesia) in ICD-11. A significant part of the workshop will be devoted to questions and answers and open discussion about advantages and limitations of the current international classification systems.
- WS1-1
- CLINICAL ASPECTS OF TAXONOMY OF SUBSTANCE USE DISORDERS: BETWEEN SEMANTICS AND LOGIC, ICD-11 AND ITS COMPARISON WITH ICD-10 AND DSM-5
- Wojciech E. Kosmowski
- Department of Psychiatry CM Bydgoszcz, Nicolaus Copernicus University, Poland
- WS1-2
- GAMBLING AND GAMING DISORDER AS ADDICTION BEHAVIOR IN ICD-11 AND DSM-5: SIMILARITIES AND DIFFERENCES
- Kristiana Siste Kurniasanti
- Psychiatry, Universitas Indonesia, Indonesia
ISBRA-WHO Workshop 2
Sunday, September 9, 15:30-17:00 Room B-1
Alcohol and Drug Epidemiology to Inform Policy Development: How to Conduct Relevant Epidemiological Research on Substance Use and Substance Use Disorders
- Facilitator:
-
Hans Jurgen Rumpf University of Lubeck, Department of Psychiatry and Psychotherapy, Germany
In general, epidemiological studies investigate distributions and determinants of health conditions. These investigations can be related to whole populations or specific subgroups. Epidemiology in the field of alcohol and drugs serves a number of purposes. Prevalence estimations and respective trends are needed to inform health professionals and policy makers of areas that need special attention. Analytical epidemiology enables to find risk factors and resilience mechanisms. This kind of information can be used for prevention and treatment. In addition, epidemiological data can inform on needs for specific services, e.g. in health care. In this workshop, two junior scientists present their work from different areas and by using different methodological approaches. One study comes from Nepal and investigates profiles of alcohol dependent patients submitted to a deaddiction ward. The second presentation is on a large-scale investigation using data from a Chinese biobank. In this investigation, the risk of different cancers in relation to alcohol consumption will be presented. Participants of the workshop will have the opportunity to highlight strengths of the papers and to develop suggestions for future projects. In addition, basic information on methods related to the two examples will be presented.
- WS2-1
- PROFILE OF ALCOHOL-DEPENDENT PATIENTS ADMITTED IN DEADDICTION WARD OF A TERTIARY LEVEL HOSPITAL IN NEPAL
- Sagun B. Pant
- Department of Psychiatry and Mental Health, Institute of Medicine, Tribhuvan University Teaching Hospital, Nepal
- WS2-2
- ALCOHOL DRINKING AND RISK OF CANCERS: FINDINGS FROM THE CHINA KADOORIE BIOBANK
- Pek Kei Im
- Nuffield Department of Population Health, University of Oxford, UK
ISBRA-WHO Workshop 3
Monday, September 10, 9:50-11:20 Room B-1
Reliable and Accurate Brief Assessment of Alcohol Use and Alcohol Use Disorders in Health Care Settings
- Facilitator:
-
John B. Saunders Centre for Youth Substance Abuse Research, University of Queensland, Australia
In this workshop approaches to undertaking accurate assessment of alcohol use disorders in various settings will be examined. In his introduction Dr. John Saunders (Australia) will canvass the many health care settings where these disorders may be identified and the use of the AUDIT questionnaire to do so. The purpose and nature of the assessment will differ in these settings, as will the nature of the intervention. Dr. Woraphat Ratta-Apha (Thailand) will present on screening for unhealthy alcohol use in general hospital patients. Dr. Tomohiro Shirasaka (Japan) will describe the approach in Japan to assess alcohol use disorders in patients with comorbid mental health disorders and early intervention for alcohol use disorders. Dr. Stephanie Baggio (Switzerland) will report on the use of the DSM-5 criteria to assess alcohol use disorder and notes a high false-positive rate with the recommended cut-off threshold of two features. Dr. Satti Sitanggang (Indonesia) reports on the problems associated with illegal alcohol consumption in Indonesia and the need for a concise assessment tool (and brief intervention) particularly directed at those consuming alcohol occasionally and who are particularly likely to consume products with toxic additives.
- WS3-1
- ASSESSMENT OF ALCOHOL USE DISORDERS IN DIFFERENT HEALTH CARE SETTINGS
- John B. Saunders
- Centre for Youth Substance Abuse Research, University of Queensland, Australia
- WS3-2
- SCREENING FOR UNHEALTHY ALCOHOL USE IN GENERAL HOSPITAL PATIENTS
- Woraphat Ratta-Apha
- Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
- WS3-3
- ASSESSING ALCOHOL USE IN PATIENTS WITH COMORBID MENTAL HEALTH DISORDERS IN JAPAN: EARLY INTERVENTION OF ALCOHOLISM FROM THE GENERAL HOSPITAL IN JAPAN
- Tomohiro Shirasaka
- Department of Psychiatry, Teine Keijinkai Hospital, Sapporo, Japan
- WS3-4
- SELF-REPORTED DSM-5 ELEVEN CRITERIA TO ASSESS ALCOHOL USE DISORDER: IS IT A RELIABLE AND ACCURATE BRIEF ASSESSMENT? EVIDENCE FROM A COMMUNITY-BASED SAMPLE
- Stéphanie Baggio
- Geneva University Hospitals, Switzerland
- WS3-5
- DEATH CAUSED BY 'OPLOSAN' (HIGH CONCENTRATION AND MIXED FORMULA) ALCOHOL IN INDONESIA
- Satti R. Sitanggang
- Psychiatric Division of Pambalah Batung General Hospital, Indonesia
ISBRA-WHO Workshop 4
Monday, September 10, 13:00-14:30 Room B-1
Translating Evidence into Practice in Different Health Care Systems: Focus on Brief Interventions and Cognitive Behavioural Therapies in the Management of Alcohol Use and Alcohol Use Disorders
- Facilitators:
-
Michie N. Hesselbrock Department of Psychiatry, University of Connecticut School of Medicine, USA Victor M. Hesselbrock Department of Psychiatry, University of Connecticut School of Medicine, USA
While the evidence for prevention of alcohol misuse and treatment of alcohol use disorders continues to grow, there remain significant delays in translating effective strategies into health care practice settings throughout the world. It is important for the research field to be aware of current evidence, to build upon it, but it is also crucial for investigators to be aware of gaps in implementation and increase knowledge and action regarding closing those gaps. This session will include both a review of the literature on the current state of translating research on treatment of alcohol use disorders and prevention of at-risk drinking into practice, and an interactive discussion of ideas for research questions that will lead to improvements in health service delivery.
Two presentations will highlight current issues in research translation. The first will show how an approach using a mindfulness-based cognitive behavioral intervention was implemented in health treatment settings in the U.S. and whether it was effective in preventing relapse. This is a significant research question, as relapse is a persistent problem during recovery from alcohol use disorder. The second will present data from a study of an aromadiagnostic approach for identifying mood issues in women in treatment for alcohol dependence and alcohol withdrawal syndrome in a psychiatric/narcologic hospital in Uzbekistan. Aromatherapy and aromadiognistic approaches are used in parts of Russia, Kazakhstan, Uzbekistan, and many parts of Asia. Their adoption by the medical establishment in North America and Western Europe is beginning to grow and will depend upon more research on effectiveness and best implementation strategies.
- WS4-1
- MINDFULNESS-BASED RELAPSE PREVENTION FOR ALCOHOL USE DISORDER: A NOVEL APPROACH FOR TREATMENT IN DIVERSE HEALTH CARE SETTINGS
- Katie Witkiewitz
- University of New Mexico, USA
- WS4-2
- AROMATHERAPY IN THE COMPLEX TREATMENT OF EMOTIONAL DISORDERS IN THE STRUCTURE OF ALCOHOL ABSTINENCE SYNDROME
- Azizbek A. Ismatov
- Department of Psychiatry and Narcology, Tashkent Medical Academy, Uzbekistan
ISBRA-WHO Workshop 5
Monday, September 10, 14:50-16:20 Room B-1
How to Increase Treatment Coverage for Alcohol Use Disorders
- Facilitator:
-
Karl F. Mann Central Institute of Mental Health, University of Heidelberg, Germany
Treatment for Alcohol Use Disorders (AUD) works reasonably well. However, too few people get engaged into treatment for different reasons. This phenomenon has been called "treatment gap" and was shown in independent studies around the world to be in the order of 80 to 90%. In other works, only 10 to 20% of individuals in need are really being treated. In the introductory presentation it shall be outlined what reasons might be driving the gap and what can be done about it. Several attempts have shown promise such as the motivational strategies, systematic involvement of relatives and harm reduction strategies. One approach has gained new momentum through the initiative of the European Medicines Agency (EMA). Snice 2010 they accept intermediate treatment goals such as the reduction of drinking without having to follow a strict abstinence orientation from the beginning. A number of analyses show that even alcohol dependent patients can reduce their consumption over time with benefits in terms of improved biomarkers, morbidity and quality of life.
The introduction will be followed by two presentations from participants of the workshop and an intense discussion with all people taking part in the workshop.
- WS5-1
- TREATMENT OF PATIENTS WITH MULTIPLE SUBSTANCE USE DISORDERS
- Mirjana Delic
- Center for Treatment of Drug Addiction, University Psychiatric Hospital Ljubljana, Slovenia
- WS5-2
- HOW TO INCREASE TREATMENT COVERAGE FOR ALCOHOL DEPENDENT PATIENTS - SPECIAL POPULATIONS IN POLAND
- Michal J. Turczynowicz-Kosmowski
- Faculty of Law, University of Warsaw, Poland
ISBRA-WHO Workshop 6
Monday, September 10, 16:30-18:00 Room B-1
How to Prepare an Effective Scientific Papers and Conference Presentations
- Facilitator:
-
Michie N. Hesselbrock Department of Psychiatry, University of Connecticut School of Medicine, USA
This will be a master technical workshop for investigators who are interested in improving their skills preparing PowerPoint slide presentations at professional meetings and in advancing their technical skills in preparing manuscripts for publication in scientific journals. The workshop will focus heavily on newer investigators (including post-docs) and non-native English speaking investigators.
The major objective of the proposed workshop will be to provide a 'hands on' experience for clinicians and researchers who have knowledge of basic and clinical research methodologies and who are interested in developing more advanced skills in the public dissemination of their scientific work.
The session will include interactive lectures by journal editors and senior investigators focusing on skill building in preparing both PowerPoint presentations and scientific manuscripts as well as interactive question and answer opportunities between senior investigators/editors and the participants. Participants will be asked to bring research ideas and barriers they have encountered when preparing manuscripts and presentations.
The agenda includes:
• Preparing effective presentations
• Description of the peer review process and the journal editor's role
• Advice from current journal editors
• Common problems encountered by new and non-English speaking authors
Senior Investigators
- Marc Schuckit, MD
- University of California, San Diego, USA
- Kathy Bucholz, PhD
- Washington University, St. Louis, USA
- Victor Hesselbrock, PhD
- University of Connecticut, USA
- Michie Hesselbrock, PhD
- University of Connecticut, USA
Acknowledgment: Funding for this conference was made possible (in part) by grants R13AA022578 and R13AA020691 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
The 13th International Symposium on ALPD and Cirrhosis
Sunday, September 9, Room C-2
- Organizers:
- Michio Imawari, Yoshiyuki Takei, Sam Zakhari, Bin Gao, Hide Tsukamoto
*Keynote speakers: 30 min talk plus 5min Q&A
Others: 20 min talk plus 5 min Q&A;
Young investigators: 10 min talk plus 5 min Q&A
- 13:15-13:30
- Opening remarks
Hide Tsukamoto/Kathy Jung
Session-1: Gut Dysbiosis and Alcoholic Liver Disease (ALD)
- Moderators:
- Michio Imawari and Hide Tsukamoto
- 13:30-14:05
- Akkermansia muciniphila and alcoholic liver disease
*Herbert Tilg
- 14:05-14:30
- Gut dysbiosis, nuclear transglutaminase and hepatocyte death
Soichi Kojima
- 14:30-14:55
- Circadian clock and dysbiosis in ALD
Ali Keshavarzian
Break (15min)
- 15:10-15:45
- The roles and mechanisms of cellular senescence in obesity-associated liver cancer
*Eiji Hara
- 15:45-16:20
- Gut dysbiosis and alconolic liver disease (ALD)
*Bernd Schnabl
- 16:20-17:00
- Two young investigators selected from submitted abstracts
Monday, September 10 Room C-2
Session-2: Alcohol, Inflammation and Organ Crosstalk
- Moderators:
- Kenichi Ikejima and Bin Gao
- 8:30-8:55
- Sterile inflammation in ASH and NASH
Wajahat Zafar Mehal
- 8:55-9:20
- Alcohol, inflammation, and organ cross-talk
Laura Nagy
- 9:20-9:45
- Alcohol-induced liver-lung interactions
Gavin Arteel
- 9:45-10:10
- Proteostasis: an important regulator of inflammation in ALD
Pranoti Mandrekar
Break (15min)
- 10:25-10:50
- IL-17 links liver inflammation to alcohol dependence
Tatiana Kisseleva
- 10:50-11:15
- ROS generation via endocytosis of TLR4-NOX2 in macrophages
Won-Il Jeong
- 11:15-11:40
- Extracelluar vesicle miRNAs in alcoholic steatohepatitis
Akiko Eguchi
- 11:40-12:05
- Role of autophagy in alcohol-induced adipose atrophy and liver injury
Wen-Xing Ding
Session-3: Alcohol, Metabolic Reprogramming, and Malignancies
- Moderators:
- Helmut Seitz and Makiko Taniai
- 13:15-13:40
- Cell fate and metabolic reprogramming of tumor-initiating stem-like cells
Keigo Machida
- 13:40-14:05
- Hepatic steatosis and impaired glucose homeostasis
Won Kim
- 14:05-14:30
- Lipidomic abnormalities in ASH
Puneet Puri
- 14:30-14:55
- Role of cytoglobin in stellate cell activation, liver fibrosis, and cancer development
Norifumi Kawada
Break (15min)
- 15:10-15:45
- Treatment of liver fibrosis and cirrhosis
*David Brenner
- 15:45-16:10
- microRNA in alcohol induced liver injury
Li Wang
- 16:10-16:35
- Promotion of pancreatic cancer development by alcohol and Western diet feeding
Kinji Asahina
- 16:35-17:05
- Two selected young investigators from submitted abstracts
- 17:05-17:15
- The 14th (2020) ALPD symposium announcement
Dong Joon Kim
- 17:15-17:20
- Closing Remarks
Yoshiyuki Takei