Program

=English Session

Presidential Lecture

Thursday, October 13th 13:45-14:15

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Leukemogenesis by RUNX1-EVI1 and afterward stories ~ a message to young doctors and researchers~

Chair: Fumimaro Takaku  
President, The Japanese Association of Medical Sciences
Speaker : Kinuko Mitani  
Department of Hematology and Oncology, Dokkyo Medical University School of Medicine

Special Lecture

Thursday, October 13th 14:15-14:55

No.1 (Main Hall, 1F, PACIFICO Yokohama)

The Non-Coding RNA revolution in biomedical research

Chair: Yuzuru Kanakura  
Department of Hematology & Oncology, Osaka University Graduate School of Medicine
Speaker : Pier Paolo Pandolfi  
Genetics, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical Center / Harvard Medical School, USA

ASH Special Lecture

Friday, October 14th 11:20-12:00

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Novel therapies for treating ITP

Chair: Shinji Nakao  
Hematology / Respirology, Faculty of Medicine, Institute of Medicine, Pharmaceutical and Health Sciences, Kanazawa University
Speaker : Charles Abrams  
Hematology / Oncology, Department of Medicine, University of Pennsylvania, USA

EHA Special Lecture

Thursday, October 13th 11:20-12:00

No.1 (Main Hall, 1F, PACIFICO Yokohama)

The myeloproliferative neoplasms - JAK/STAT signalling and stem cell subversion

Chair: Itaru Matsumura  
Department of Hematology & Rheumatology, Kindai University Faculty of Medicine
Speaker : Tony Green  
Department of Haematology, University of Cambridge, UK

JSH Award Lecture

Saturday, October 15th 11:25-12:10

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Chair : Koichi Akashi  
Department of Medicine and Biosystemic Science, Faculty of Medicine, Kyushu University

Molecular mechanisms that regulate hematopoietic stem cell and its disorder

Speaker : Yuzuru Kanakura  
Department of Hematology & Oncology, Osaka University Graduate School of Medicine

Presidential Symposium

Thursday, October 13th 15:10-17:20

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Dysregulation of RNA in hematological malignancies

Chairs: Koichi Akashi  
Department of Medicine and Biosystemic Science, Faculty of Medicine, Kyushu University

Kinuko Mitani  
Department of Hematology and Oncology, Dokkyo Medical University School of Medicine

Runx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells

Speaker : Nancy A. Speck   
Abramson Family Cancer Research Institute and Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, USA

Epigenetic regulation by noncoding RNA

Speaker : Daniel G. Tenen   
Cancer Science Institute of Singapore, Singapore

Understanding and targeting spliceosomal gene mutations in cancer

Speaker : Omar Abdel-Wahab   
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, USA

A novel genetic mechanism of evading anti-tumor immunity in multiple human cancers

Speaker : Seishi Ogawa  
Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University

JSH-ASH Joint Symposium(Symposium 8)

Saturday, October 15th 9:00-11:10

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Molecular heterogeneity and target therapies of malignant lymphoma in new WHO classification era

Chairs: Charles Abrams  
Hematology / Oncology, Department of Medicine, University of Pennsylvania, USA

Tomohiro Kinoshita  
Department of Hematology, Aichi Cancer Center Hospital

Pathology side: A focused update of the revised WHO classification of lymphoid neoplasms

Speaker : Elaine S. Jaffe  
Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, USA

Genetic heterogeneity of DLBCL

Speaker : Kennosuke Karube  
Department of Pathology and Cell Biology, Graduate School of Medicine and Faculty of Medicine, University of the Ryukyus

Progress in the management of ATL

Speaker : Kenji Ishitsuka  
Division of Hematology and Immunology, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University

Clinical side: New target therapies for malignant lymphoma based on molecular heterogeneity

Speaker : Jonathan W. Friedberg  
University of Rochester, Wilmot Cancer Center, USA

JSH-EHA Joint Symposium(Symposium 4)

Friday, October 14th 9:00-11:10

No.1 (Main Hall, 1F, PACIFICO Yokohama)

AML with recurrent genetic abnormality in WHO2016

Chairs: Tony Green  
Department of Haematology, University of Cambridge, UK

Hitoshi Kiyoi  
Department of Hematology and Onclogy, Nagoya University Graduate School of Medicine

Current treatment of acute promyelocytic leukemia

Speaker : Miguel A. Sanz  
Department of Hematology, University Hospital La Fe, Spain

Pediatric AML with genetic alterations

Speaker : Akira Shimada  
Department of Pediatrics/Pediatric Hematology/Oncology, Okayama Universitry Hospital

KIT inhibition in core-binding factor

Speaker : Peter Paschka  
Department of Internal Medicine III, University of Ulm, Germany

Cooperative mutations in AML with recurrent genetic abnormality

Speaker : Yuichi Ishikawa  
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine

Asian Joint Panel Discussion

Saturday, October 15th 9:00-11:10

No.3 (303, 3F, PACIFICO Yokohama)

Recent progresses in the treatment of immune thrombocytopenia and coagulopathy in Asia

Chairs : Sun-Hee Kim  
Department of Laboratory Medicine, Samsung Medical Center

Akitada Ichinose  
Department of Molecular Patho-Biochemistry and Patho-Biology, Yamagata University School of Medicine

Clinical diagnosis and genetics of von Willebrand disease

Speaker : Yeu-Chin Chen  
Hemophilia Care & Research Center /
Division of Hematology / Oncology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

Challenges in diagnosis and treatment of immune thrombocytopenia (ITP)

Speaker : Ponlapat Rojnuckarin  
Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand

T cells in the pathogenesis of immune thrombocytopenia

Speaker : Hou Ming  
Department of Hematology, Qilu Hospital, Shandong University, Jinan, China / Shandong Provincial Key Laboratory of Immunohematology, Qilu Hospital, Shandong University, Jinan, China

Current status of ITP in Korea

Speaker : Soo-Mee Bang  
Seoul National University Bundang Hospital, Seongnam, Korea

Immune thrombocytopenic purpura: Challenges in management in Indian context

Speaker : Manoranjan Mahapatra  
Department of Hematology, All India Institute of Medical Sciences, New Delhi, India

Management of direct oral anticoagulant - Associated bleeding

Speaker : Lee Lai Heng  
Singapore General Hospital

Quick diagnosis for coagulation disorders with prolouged APTT using comprehensive coagulation assays

Speaker : Keiji Nogami  
Department of Pediatrics, Nara Medical University

Symposium

Symposium 1

Thursday, October 13th 9:00-11:10

No.2 (301+302, 3F, PACIFICO Yokohama)

Transcriptional regulation in hematopoiesis and leukemogenesis

Chairs: Hideyo Hirai  
Department of Transfusion Medicine and Cell Therapy, Kyoto University Hospital

Shigeru Chiba  
Department of Hematology, Faculty of Medicine, University of Tsukuba

A single miRNAs rescue transcriptional factor deficiency in B cell lineage specification though TGF beta pathway

Speaker : Ai Kotani  
Devision of Hematological Malignancy Institute of Medical Science, Tokai University

The transcription factor IRF8 and enhancer landscape dynamics in the development of mononuclear phagocytes

Speaker : Tomohiko Tamura  
Department of Immunology, Yokohama City University Graduate School of Medicine

Transcriptional and epigenetic dysregulation in pre-leukemic stem cells and their progression to MDS and AML

Speaker : Ulrich Steidl  
Department of Cell Biology, and Medicine (Oncology), Albert Einstein College of Medicine, USA

Chromosomal rearrangements between 3q21 and 3q26 induce leukemogenesis by misdirecting both EVI1 and GATA2 genes

Speaker : Mikiko Suzuki  
Center for Radioisotope Sciences, Tohoku University Graduate School of Medicine

Mechanistic insights into aberrant chromatin programming in Leukemia

Speaker : Constanze Bonifer  
Institute for Cancer and Genomic Sciences, University of Birmingham, UK

Symposium 2

Thursday, October 13th 9:00-11:10

No.12 (501, 5F, PACIFICO Yokohama)

Molecular mechanisms of erythropoiesis - Differentiation, iron metabolism, and eryptosis

Chairs: Hiroshi Kawabata   
Department of Hematology and Immunology, Kanazawa Medical University

Ritsuko Shimizu  
Department of Molecular Hematology, Tohoku University Graduate School of Medicine

Transcriptional regulation of erythropoiesis

Speaker : Tohru Fujiwara  
Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine

Alternative autophagy mediates elimination of mitochondria from embryonic reticulocytes

Speaker : Shigeomi Shimizu  
Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University

Mechanisms and pathophysiological significance of eryptosis

Speaker : Florian Lang  
Department of Physiology, Eberhard-Karls-University of Tuebingen, Germany

Identification of erythroferrone and its role in iron metabolism

Speaker : Tomas Ganz  
Department of Medicine, David Geffen School of Medicine, UCLA, USA

Symposium 3

Thursday, October 13th 15:10-17:20

No.12 (501, 5F, PACIFICO Yokohama)

Advances in tumor immunology

Chairs: Kenzaburo Tani   
Project Division of ALA Advanced Medical Research, The Institute of Medical Science, The University of Tokyo

Norimitsu Kadowaki  
Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University

PD-1 blockade for Hodgkin lymphoma

Speaker : Stephen M. Ansell  
Division of Hematology, Mayo Clinic, USA

Clinical development of immune checkpoint inhibitors and TR research

Speaker : Shigehisa Kitano  
Department of Experimental Therapeutics, National Cancer Center Hospital

Engineered T cell therapy

Speaker : Carlos A. Ramos  
Center for Cell and Gene Therapy, Hematology/Oncology, Department of Medicine, Baylor College of Medicine, USA

T-cell receptor repertoire diversity in patients with ATL who receive mogamulizumab

Speaker : Ayako Masaki  
Department of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences

Oncolytic Coxsackievirus therapy as an immunostimulator

Speaker : Shohei Miyamoto  
Project Division of ALA Advanced Medical Research, The Institute of Medical Science,The University of Tokyo

Symposium 5

Friday, October 14th 14:50-17:00

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Clinical aspects and basic research of MDS: Current situation and future

Chairs: Mikkael A. Sekeres  
Leukemia Program, Hematology and Medical Oncology, Cleveland Clinic, USA

Mamiko Sakata-Yanagimoto  
Department of Hematology, Faculty of Medicine, University of Tsukuba

Pre-leukemic hematopoietic stem cells in human acute myeloid leukemia

Speaker : Ravi Majeti  
Medicine - Hematology, Stanford University, USA

Deregulated polycomb function in the pathogenesis of MDS

Speaker : Atsushi Iwama  
Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University

Bone marrow failure in childhood: pathological review of nationwide registry

Speaker : Masafumi Ito  
Department of Pathology, Japanese Red Cross, Nagoya 1st. Hospital

Novel agents in the treatment of myelodysplastic syndromes

Speaker : Mikkael A. Sekeres  
Leukemia Program, Hematology and Medical Oncology, Cleveland Clinic, USA

Symposium 6

Friday, October 14th 14:50-17:00

No.2 (301+302, 3F, PACIFICO Yokohama)

Cutting edge of stem cell transplantations

Chairs: Yoshinobu Maeda  
Department of Hematology and Oncology, Okayama University Hospital

Takehiko Mori  
Division of Hematology, Keio University School of Medicine

Donor cell-derived hematological malignancy

Speaker : Motohiro Kato  
Children's Cancer Center, National Center for Child Health and Development

Respiratory virus infections in hematopoietic cell transplant recipients

Speaker : Sachiko Seo  
Department of Hematology & Oncology, National Cancer Research Center, East Hospital

Graft-versus-host disease targets granulosa cell of ovarian follicle and causes infertility after allogeneic hematopoietic stem cell transplantation

Speaker : Sonoko Shimoji  
Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences

Gut microbiota and graft-versus-host disease – effects of broad-spectrum antibiotic use on microbiota injury after allogeneic hematopoietic stem cell transplantation

Speaker : Yusuke Shono  
Memorial Sloan Kettering Cancer Center, USA

Novel cytokine and cellular therapy in transplantation

Speaker : Geoffrey R. Hill  
Department of Immunology, QIMR Berghofer Medical Research Institute, Australia

Symposium 7

Friday, October 14th 9:00-11:10

No.14 (503, 5F, PACIFICO Yokohama)

Guidelines on thrombotic and hemorrhagic diseases

Chairs: Tsukasa Ohmori  
Department of Biochemistry, Jichi Medical University School of Medicine

Hidesaku Asakura  
Department of Internal Medicine(III), Kanazawa University School of Medicine

Practical Guide for the management of adult primary immune thrombocytopenia

Speaker : Yoshiaki Tomiyama  
Department of Blood Transfusion, Osaka University Hospital

Guide for Managing TTP and aHUS

Speaker : Hideo Wada  
Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine

Congenital and acquired hemophilia

Speaker : Satoshi Higasa  
Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine

Congenital thormbophilia

Speaker : Eriko Morishita  
Department of Clinical Laboratory Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, USA

Clinical guidance of venous thromboembolism (VTE)

Speaker : Takao Kobayashi  
Hamamatsu Medical Center

Symposium 9

Saturday, October 15th 13:20-15:30

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Initial treatment for multiple myeloma: proteasome inhibitor first or immunomodulatory drug first?

Chairs: Shinsuke Iida  
Department of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences

Yasushi Takamatsu  
Division of Medical Oncology, Hematology and Infections Diseases, Department of Medicine, Fukuoka University

First-line treatment incorporating proteasome inhibitor for multiple myeloma

Speaker : Junya Kuroda  
Division of Hematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine

Clinical trials of IMiD® agents as the first-line therapy of multiple myeloma

Speaker : Thierry Facon  
Lille University Hospital, France

Clinical trials of proteasome inhibition combined with IMiD in multiple myeloma

Speaker : Pieter Sonneveld  
Department of Hematology, Erasmus MC Cancer Institute, Netherlands

Combination therapy with monoclonal antibodies for the treatment of newly diagnosed multiple myeloma

Speaker : Noriko Nishimura  
Division of Hematology / Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research

Treatment algorithm of multiple myeloma in Japan

Speaker : Shuji Ozaki  
Department of Hematology, Tokushima Prefectural Central Hospital

Symposium 10

Saturday, October 15th 13:20-15:30

No.13 (502, 5F, PACIFICO Yokohama)

Current status and prospects of treatment for adolescent and young adults with hematological malignancies

Chairs: Keizo Horibe  
Clinical Research Center, Nagoya Medical Center

Souichi Adachi  
Human Health Sciences, Graduate School of Medicine, Kyoto University

Treatment of ALL in AYA generation: From the viewpoint of pediatric hematologist

Speaker : Katsuyoshi Koh  
Department of Hematology / Oncology, Saitama Children's Medical Center

Genetic abnormalities of AYA ALL and its treatment strategy by pediatric like protocols

Speaker : Fumihiko Hayakawa  
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine

Acute myeloid leukemia in adolescents and young adults: from a viewpoint of pediatric hematologist/oncologist

Speaker : Daisuke Tomizawa  
Children's  Cancer Center, National Center for Child Health and Development

AYAs with AML: Perspectives of internal medicine physicians

Speaker : Yachiyo Kuwatsuka  
Center for Advanced Medicine and Clinical Research, Nagoya University Hospital

Lymphoma of AYA generation: from pediatrician

Speaker : Ryoji Kobayashi  
Department of Pediatrics, Sapporo Hokuyu Hospital

Adolescent and young adult malignant lymphoma: from a hemato-oncologist’s point of view

Speaker : Dai Maruyama  
Department of Hematology, National Cancer Center Hospital

Symposium of Women Doctors and Scientists in Hematology

Saturday, October 15th 9:00-11:00

No.13 (502, 5F, PACIFICO Yokohama)

Symposium of Women Doctors and Scientists in Hematology ~women doctors opening a new era~

Chairs: Noriko Usui  
Department of Clinical Oncology and Hematology, The Jikei University Daisan Hospital

Masahiro Kizaki  
Department of Hematology, Saitama Medical Center, Saitama Medical University

Origins and evolution of hematologic malignancies

Speaker : Mamiko Sakata-Yanagimoto  
Department of Hematology, Faculty of Medicine, University of Tsukuba

To achieve safer hematopoietic cell transplantations

Speaker : Sachiko Seo  
Department of Hematology & Oncology, National Cancer Research Center, East Hospital

Hematopoietic cell transplantation outcome registry and clinical research

Speaker : Yoshiko Atsuta  
The Japanese Data Center for Hematopoietic Cell Transplantation

Dissecting the pathogenesis of lymphoid malignancies

Speaker : Momoko Nishikori  
Department of Hematology / Oncology, Kyoto University

Devoting half a life to overcome "lethal" diseases

Speaker :Motoko Yamaguchi  
Department of Hematology and Oncology, Mie University Graduate School of Medicine

Impact of chromosome translocation in leukemia development

Speaker : Mariko Eguchi  
Department of Pediatrics, Ehime University Graduate School of Medicine

Plenary Session

Friday, October 14th 13:10-14:40

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Chairs: Masahiro Kizaki  
Department of Hematology, Saitama Medical Center, Saitama Medical University

Takanori Teshima  
Department of Hematology, Hokkaido University Graduate School of Medicine

Novel leukemia stem cell-targeted therapy for AML based on dual inhibition of EZH1/EZH2

Speaker : Shuhei Fujita  
Division of Hematological Malignancy, National Cancer Center Research Institute, Tokyo, Japan

The transcriptional and alternative splicing landscape of myelodysplastic syndromes

Speaker : Yusuke Shiozawa  
Department of Pediatrics, Tokyo University, Tokyo, Japan

Clinical features and prognosis of unselected patients with AML and RAEB-2: JALSG CS07 study

Speaker : Yasushi Miyazaki  
Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan

The C/EBPβ transcription factor mediates exhaustion of CML stem cells induced by IFNα

Speaker : Asumi Yokota  
Department of Transfusion Medicine & Cell Therapy, Kyoto University Hospital, Kyoto, Japan

LGR5+ skin stem cells are targeted in GVHD and topical ruxolitinib protects them against GVHD

Speaker : Shuichiro Takahashi  
Department of Hematology, Hokkaido University Graduate School of Medicine

New era of platelet biogenesis with a large scale bioreactor optimizing flow and vortex turbulence

Speaker : Sou Nakamura  
Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto

Educational Lecture / Special Educational Lecture

Educational Lecture 1

Thursday, October 13th 9:00-9:30

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Treatment strategy in untreated transplant-eligible multiple myeloma patients

Chair : Akiyoshi Miwa  
Department of Hematology, National Center for Global Health & Medicine
Speaker : Kazutaka Sunami  
Department of Hematology, National Hospital Organization Okayama Medical Center

Educational Lecture 2

Thursday, October 13th 9:30-10:00

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Treatment strategy for transplant-ineligible patients with newly diagnosed multiple myeloma

Chair : Yukio Kobayashi  
Hematology Division, National Cancer Center Hospital
Speaker : Hideto Tamura  
Division of Hematology,Department of Medicine, Nippon Medical School

Educational Lecture 3

Thursday, October 13th 10:00-10:30

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Current treatment of refractory and relapsed multiple myeloma

Chair : Kenshi Suzuki  
Japanese Red Cross Medical Center
Speaker : Makoto Sasaki  
Department of Hematology, Juntendo University School of Medicine

Special Educational Lecture 4

Thursday, October 13th 10:30-11:10

No.1 (Main Hall, 1F, PACIFICO Yokohama)

Structure-guided research and development of therapeutics for HIV infection & AIDS: Attempts by one hematologist

Chair : Keiya Ozawa  
Division of Genetic Therapeutics, The Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo
Speaker : Hiroaki Mitsuya  
National Center for Global Health & Medicine Research Institute, Tokyo, Japan /
National Cancer Institute, National Institutes of Health, Bethesda, MD, USA /
Kumamoto University School of Medicine Hospital, Kumamoto, Japan

Educational Lecture 5

Thursday, October 13th 15:10-15:40

No.2 (301+302, 3F, PACIFICO Yokohama)

Clinical manifestation and treatment of extranodal diffuse large B-cell lymphoma

Chair : Kunihiro Tsukasaki  
Department of Hematology, National Cancer Center Hospital East
Speaker : Naoto Tomita  
Division of Hematology and Oncology, Department of Internal Medicine, St. Marianna University School of Medicine

Educational Lecture 6

Thursday, October 13th 15:40-16:10

No.2 (301+302, 3F, PACIFICO Yokohama)

Progress in the treatment of mature T-cell lymphoma

Chair : Kazuo Oshimi  
Department of Hematology, Kushiro Rosai Hospital
Speaker : Ritsuro Suzuki  
Department of Oncology and Hematology, Shimane University Cancer Center

Educational Lecture 7

Thursday, October 13th 16:10-16:40

No.2 (301+302, 3F, PACIFICO Yokohama)

Update on the use of FDG-PET/CT in malignant lymphoma

Chair : Koji Izutsu  
Department of Hematology, Toranomon Hospital
Speaker : Takashi Terauchi  
Department of Nuclear Medicine, Cancer Institute Hospital, Japanese Foundation for Cancer Research

Educational Lecture 8

Thursday, October 13th 16:40-17:10

No.2 (301+302, 3F, PACIFICO Yokohama)

Development of novel combination therapy for lymphoma based on preclinical models

Chair : Junji Suzumiya  
Oncology & Hematology, Shimane University Hospital Cancer Center
Speaker : Owen A. O'Connor  
Columbia University College of Physicians and Surgeons

Educational Lecture 9

Thursday, October 13th 9:00-9:30

No.13 (502, 5F, PACIFICO Yokohama)

A primer for epigenetics of hematological malignancies

Chair : Mineo Kurokawa  
Department of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo
Speaker : Hideaki Nakajima  
Department of Stem Cell and Immune Regulation Yokohama City University Graduate School of Medicine

Educational Lecture 10

Thursday, October 13th 9:30-10:00

No.13 (502, 5F, PACIFICO Yokohama)

Self-renewal and differentiation of hematopoietic stem cells

Chair : Atsushi Hirao  
Division of Molecular Genetics, Cancer Research Institute, Kanazawa University
Speaker : Fumio Arai  
Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University

Educational Lecture 11

Thursday, October 13th 10:00-10:30

No.13 (502, 5F, PACIFICO Yokohama)

Myeloproliferative neoplasms: updates on molecular pathophysiology, diagnosis and treatment strategies

Chair : Norio Komatsu  
Department of Hematology, Juntendo University School of Medicine
Speaker : Katsuto Takenaka  
Center for Molecular and Cellular Medicine, Kyushu University Hospital

Educational Lecture 12

Thursday, October 13th 10:30-11:00

No.13 (502, 5F, PACIFICO Yokohama)

The essence of leukemia stem cells

Chair : Toshio Suda  
National University of Singapore / IRCMS, Kumamoto University
Speaker : Susumu Goyama  
Division of Cellular Therapy, The Institute of Medical Science, The University of Tokyo

Educational Lecture 13

Thursday, October 13th 15:10-15:40

No.13 (502, 5F, PACIFICO Yokohama)

Von Willebrand factor and von Willebrand disease

Chair : Akira Yoshioka  
Nara Medical University
Speaker : Taei Matsui  
Faculty of Medical Technology, Fujita Health University School of Health Sciences

Educational Lecture 14

Thursday, October 13th 15:40-16:10

No.13 (502, 5F, PACIFICO Yokohama)

Spontaneous heparin-induced thrombocytopenia (HIT) syndrome: HIT without any heparin exposure

Chair : Mitsuru Murata   
Department of Laboratory Medicine, Keio University School of Medicine
Speaker : Shigeki Miyata  
Division of Transfusion Medicine, National Cerebral and Cardiovascular Center

Educational Lecture 15

Thursday, October 13th 16:10-16:40

No.13 (502, 5F, PACIFICO Yokohama)

Diagnosis and management of DIC complicated by hematological malignancies

Chair : Yoichi Sakata  
Research Division of Cell and Molecular Medicine, Center for Molecular Medicine, Jichi Medical University
Speaker : Takayuki Ikezoe  
Department of Hematology and Respiratory Medicine, Kochi Medical School, Kochi University

Educational Lecture 16

Thursday, October 13th 16:40-17:10

No.13 (502, 5F, PACIFICO Yokohama)

Exciting investigator-initiated clinical trials

Chair : Shuichi Miyawaki  
Division of Hematology, Tokyo Metropolitan Ohtsuka Hospital
Speaker : Yoshitaka Miyakawa  
Saitama Medical University

Educational Lecture 17

Thursday, October 13th 9:00-9:30

No.14 (503, 5F, PACIFICO Yokohama)

The importance of taking late cardiovascular toxicity induced by TKI into consideration in patients with CML

Chair : Kazunori Ohnishi  
Japanese Red Cross Aichi Blood Center
Speaker : Naoto Takahashi  
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine

Educational Lecture 18

Thursday, October 13th 9:30-10:00

No.14 (503, 5F, PACIFICO Yokohama)

Management of advanced-phase chronic myeloid leukemia

Chair : Masao Tomonaga  
Japanese Red Cross Nagasaki Atomic Bomb Hospital
Speaker : Akira Kitanaka  
Department of Laboratory Medicine, Kawasaki Medical School

Educational Lecture 19

Thursday, October 13th 10:00-10:30

No.14 (503, 5F, PACIFICO Yokohama)

Molecular pathogenesis of AML

Chair : Toshio Kitamura  
Division of Cellular Therapy, The Institute of Medical Science, The University of Tokyo
Speaker : Hiroaki Honda  
Department of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University

Educational Lecture 20

Thursday, October 13th 10:30-11:00

No.14 (503, 5F, PACIFICO Yokohama)

Prognostic stratification in the treatment of AML

Chair : Ryuzo Ohno  
Aichi Cancer Center
Speaker : Norio Asou  
Department of Hematology, International Medical Center, Saitama Medical University

Educational Lecture 21

Thursday, October 13th 15:10-15:40

No.14 (503, 5F, PACIFICO Yokohama)

Hematopoietic stem cell transplantation for acute myeloid leukemia

Chair : Shuichi Taniguchi  
Department of Hematology, Toranomon Hospital
Speaker : Ken Ishiyama  
Department of Hematology, Kanazawa University Hospital

Educational Lecture 22

Thursday, October 13th 15:40-16:10

No.14 (503, 5F, PACIFICO Yokohama)

Treatment of acute myeloid leukemia under relapsed/refractory conditions or in older adults

Chair : Takanori Ueda  
University of Fukui
Speaker : Takahiro Yamauchi  
Department of Hematology and Oncology, University of Fukui

Educational Lecture 23

Thursday, October 13th 16:10-16:40

No.14 (503, 5F, PACIFICO Yokohama)

Immune checkpoint inhibitors targeting programmed cell death-1 (PD-1) in cancer therapy

Chair : Hiroshi Shiku  
Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine
Speaker : Kenji Chamoto  
Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University

Educational Lecture 24

Thursday, October 13th 16:40-17:10

No.14 (503, 5F, PACIFICO Yokohama)

Direct isolation and application of ultra-pure human mesenchymal stem cells

Chair : Tatsutoshi Nakahata  
Department of Clinical Application, Center for iPS Research and Application (CiRA), Kyoto University
Speaker : Yumi Matsuzaki  
Department of Life Science, Shimane University Faculty of Medicine

Educational Lecture 25

Friday, October 14th 9:00-9:30

No.2 (301+302, 3F, PACIFICO Yokohama)

Diffuse large B-cell lymphoma: current standard treatment and future perspectives

Chair : Ryuzo Ueda  
Aichi Medical University School of Medicine
Speaker : Ken Ohmachi  
Tokai University, School of Medicine, Internal Medicine, Division of Hematology / Oncology

Educational Lecture 26

Friday, October 14th 9:30-10:00

No.2 (301+302, 3F, PACIFICO Yokohama)

The 2016 WHO Classification of lymphoid neoplasms: revised points

Chair : Tomomitsu Hotta  
National Cancer Center
Speaker : Shigeo Nakamura  
Department of Pathology and Laboratory Medicine, Nagoya University Hospital

Educational Lecture 27

Friday, October 14th 10:00-10:30

No.2 (301+302, 3F, PACIFICO Yokohama)

Mechanisms of drug resistance in acute lymphoblastic leukemia

Chair : Masafumi Taniwaki  
Center for Molecular Diagnostics and Therapeutics, Kyoto Prefectural University of Medicine
Speaker : Takeshi Inukai  
Department of Pediatrics, University of Yamanashi

Special Educational Lecture 28

Friday, October 14th 10:30-11:10

No.2 (301+302, 3F, PACIFICO Yokohama)

How has the management of Ph acute lymphoblastic leukemia (ALL) changed over the years

Chair : Yasushi Miyazaki  
Department of Hematology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University
Speaker : Robin Foà  
Hematology, Department of Cellular Biotechnologies and Hematology, Policlinico Umberto 1, “Sapienza” University

Educational Lecture 29

Friday, October 14th 9:00-9:30

No.12 (501, 5F, PACIFICO Yokohama)

Transfusion medicine in practice

Chair : Hideaki Mizoguchi  
Tokyo Women's Medical University
Speaker : Shigeyoshi Makino  
Department of Transfusion Medicine, Toranomon Hospital

Educational Lecture 30

Friday, October 14th 9:30-10:00

No.12 (501, 5F, PACIFICO Yokohama)

Investigation into the identities of circulating exosomes

Chair : Tomoki Naoe  
National Hospital Organization Nagoya Medical Center
Speaker : Takahiro Ochiya  
Division of Molecular and Cellular Medicine, National Cancer Center Research Institute

Educational Lecture 31

Friday, October 14th 10:00-10:30

No.12 (501, 5F, PACIFICO Yokohama)

Hepcidin

Chair : Hideo Harigae  
Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine
Speaker : Tomas Ganz  
David Geffen School of Medicine, UCLA, USA

Special Educational Lecture 32

Friday, October 14th 10:30-11:10

No.12 (501, 5F, PACIFICO Yokohama)

Diagnosis and treatment of HLH in adults

Chair : Masaki Yasukawa  
Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine
Speaker : Nancy Berliner  
Division of Hematology, Brigham and Women's Hospital Medicine, Harvard Medical School

Educational Lecture 33

Friday, October 14th 14:50-15:20

No.12 (501, 5F, PACIFICO Yokohama)

Diagnostics for multiple myeloma

Chair : Hirokazu Murakami  
Gunma University Graduate School of Health Sciences
Speaker : Etsuko Yamazaki  
Clinical Laboratory Department, Yokohama City University Hospital

Educational Lecture 34

Friday, October 14th 15:20-15:50

No.12 (501, 5F, PACIFICO Yokohama)

Treatment strategy of MGUS and smoldering multiple myeloma

Chair : Masayuki Hino  
Hematology, Osaka City University
Speaker : Masuzu Ueda  
Department of Clinical Oncology and Division of Hematology, Department of Medicine, Jichi Medical University

Educational Lecture 35

Friday, October 14th 15:50-16:20

No.12 (501, 5F, PACIFICO Yokohama)

Multiple myeloma: progress in management aimed at improving QoL

Chair : Akira Miura  
Social Welfare Corporation Keijinkai / National University Corporation, Akita University
Speaker : Masahiro Abe  
Tokushima University Graduate School, Department of Hematology, Endocrinology and Metabolism Medicine and Bioregulatory Sciences

Educational Lecture 36

Friday, October 14th 16:20-16:50

No.12 (501, 5F, PACIFICO Yokohama)

Functional contribution of oxidative stress response to differentiation and proliferation of hematopoietic cells

Chair : Kazuo Motoyoshi  
National Defense Medical College
Speaker : Hozumi Motohashi  
Department of Gene Expression Regulation in Institute of Development, Aging and Cancer, Tohoku University

Educational Lecture 37

Friday, October 14th 9:00-9:30

No.13 (502, 5F, PACIFICO Yokohama)

Iron deficiency anemia refractory to iron preparations

Chair : Akio Urabe  
NTT Medical Center Tokyo
Speaker : Takahiro Suzuki  
Division of Hematology, Department of Medicine, Jichi Medical University

Educational Lecture 38

Friday, October 14th 9:30-10:00

No.13 (502, 5F, PACIFICO Yokohama)

Aplastic anemia

Chair : Yutaka Kohgo  
International University of Health and Welfare Hospital
Speaker : Kensuke Usuki  
Department of Hematology, Medical Center Tokyo

Educational Lecture 39

Friday, October 14th 10:00-10:30

No.13 (502, 5F, PACIFICO Yokohama)

Pathogenesis of paroxysmal nocturnal hemoglobinuria

Chair : Mitsuhiro Omine  
Showa University Fujigaoka Hospital
Speaker : Yoshiko Murakami  
Research Institute for Microbial Diseases, Osaka University

Educational Lecture 40

Friday, October 14th 10:30-11:00

No.13 (502, 5F, PACIFICO Yokohama)

Genetic diagnosis for congenital hemolytic anemia

Chair : Kazuo Dan  
Faculty of Health Science, Ryotokuji University
Speaker : Shouichi Ohga  
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University

Educational Lecture 41

Friday, October 14th 14:50-15:20

No.13 (502, 5F, PACIFICO Yokohama)

A novel disease entity; TAFRO syndrome

Chair : Toshiko Motoji  
Tokyo Women's Medical University
Speaker : Yasufumi Masaki  
Hematology and Immunology, Medicine, Kanazawa Medical University

Educational Lecture 42

Friday, October 14th 15:20-15:50

No.13 (502, 5F, PACIFICO Yokohama)

Targeted therapies for Hodgkin lymphoma: results of recent trials

Chair : Kiyohiko Hatake  
Department of Hematology Oncology, Cancer Institute Hospital, Division of Clinical Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research
Speaker : Fredrick B. Hagemeister  
Department of Lymphoma / Myeloma, MD Anderson Cancer Center

Educational Lecture 43

Friday, October 14th 15:50-16:20

No.13 (502, 5F, PACIFICO Yokohama)

Targeting immune checkpoints in lymphoma

Chair : Mitsune Tanimoto  
Department of Hematology and Oncology, Okayama University
Speaker : Stephen M. Ansell  
Mayo Clinic

Special Educational Lecture 44

Friday, October 14th 16:20-17:00

No.13 (502, 5F, PACIFICO Yokohama)

Targeting apoptotic pathways to treat lymphoid malignancies

Chair : Kensei Tobinai  
Department of Hematology, National Cancer Center Hospital
Speaker : Andrew W. Roberts  
Department of Clinical Hematology and Bone Marrow Transplantation, The Royal Melbourne Hospital, Parkville, Victoria, Australia / Cancer and Haematology Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia / Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria, Australia / Victorian Comprehensive Cancer Centre, Parkville, Victoria, Australia

Educational Lecture 45

Friday, October 14th 14:50-15:20

No.14 (503, 5F, PACIFICO Yokohama)

How to choose and understand clinical laboratory tests in daily clinical management of hematologic diseases

Chair : Tadashi Matsushita  
Department of Transfusion Medicine, Nagoya University Hospital
Speaker : Yoshinobu Seki  
Department of Hematology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital

Educational Lecture 46

Friday, October 14th 15:20-15:50

No.14 (503, 5F, PACIFICO Yokohama)

Rare bleeding disorders: diagnosis of platelet function disorder

Chair : Yukio Ozaki  
Fuefuki Chuo Hospital
Speaker : Hisashi Kato  
Department of Hematology and Oncology, Osaka University Graduate School of Medicine

Educational Lecture 47

Friday, October 14th 15:50-16:20

No.14 (503, 5F, PACIFICO Yokohama)

Trends in novel treatments for hemophilia

Chair : Eiichi Ishii  
Department of Pediatrics, Ehime University Graduate School of Medicine
Speaker : Midori Shima  
Department of Pediatrics, Nara Medical University

Educational Lecture 48

Friday, October 14th 16:20-16:50

No.14 (503, 5F, PACIFICO Yokohama)

Epstein-Barr virus infection and related hematological diseases

Chair : Naoyuki Katayama  
Department of Hematology and Oncology, Mie University Graduate School of Medicine
Speaker : Akihisa Sawada  
Osaka Medical Center and Research Institute for Maternal and Child Health, Hematology / Oncology

Educational Lecture 49

Saturday, October 15th 9:00-9:30

No.2 (301+302, 3F, PACIFICO Yokohama)

Historical perspectives and future directions of gene-modified T-cell therapy

Chair : Arinobu Tojo  
Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo
Speaker : Yoshiki Akatsuka  
Department of Hematology, Fujita Health University School of Medicine / Division of Immunology, Aichi Cancer Center Research Institute

Educational Lecture 50

Saturday, October 15th 9:30-10:00

No.2 (301+302, 3F, PACIFICO Yokohama)

Recent insights to the mechanisms of graft-versus-host disease

Chair : Shinichiro Okamoto  
Division of Hematology, Keio Universiy School of Medicine
Speaker : Geoffrey R. Hill  
QIMR Berghofer Medical Research Institute, Department of Bone Marrow Transplantation, Royal Brisbane and Women’s Hospital

Educational Lecture 51

Saturday, October 15th 10:00-10:30

No.2 (301+302, 3F, PACIFICO Yokohama)

Treatment of acute graft-versus-host disease

Chair : Yoshinobu Kanda  
Division of Hematology, Department of Medicine, Jichi Medical University
Speaker : Makoto Murata  
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine

Special Educational Lecture 52

Saturday, October 15th 10:30-11:10

No.2 (301+302, 3F, PACIFICO Yokohama)

Update on stem cell transplantation for acute leukemias

Chair : Mine Harada  
Medical Center for Karatsu-Higashimatsuura Medical Association
Speaker : Shin Mineishi  
Blood and Marrow Transplant Program, Penn State Hershey Medical Center

Educational Lecture 53

Saturday, October 15th 13:20-13:50

No.2 (301+302, 3F, PACIFICO Yokohama)

How does HTLV-1 induce ATL?

Chair : Akifumi Takaori-Kondo  
Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University
Speaker : Masao Matsuoka  
Institute for Virus Research, Kyoto University

Educational Lecture 54

Saturday, October 15th 13:50-14:20

No.2 (301+302, 3F, PACIFICO Yokohama)

Allogeneic hematopoietic stem cell transplantation for adult T-cell leukemia-lymphoma

Chair : Tatsuo Ichinohe  
Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine (RIRBM), Hiroshima University
Speaker : Atae Utsunomiya  
Department of Hematology, Imamura bun-in Hospital

Educational Lecture 55

Saturday, October 15th 14:20-14:50

No.2 (301+302, 3F, PACIFICO Yokohama)

HTLV-1-targeted immunotherapy

Chair : Yutaka Kawakami  
Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine
Speaker : Youko Suehiro  
Department of Hematology, Department of Cell Therapy, National Kyushu Cancer Center

Educational Lecture 56

Saturday, October 15th 14:50-15:20

No.2 (301+302, 3F, PACIFICO Yokohama)

Allogeneic hematopoietic stem cell transplantation for inherited diseases

Chair : Koji Nagafuji  
Division of Hematology & Oncology, Department of Medicine, Kurume University School of Medicine
Speaker : Hiromasa Yabe  
Department of Cell Transplantation and Regenerative Medicine, Tokai University School of Medicine

Educational Lecture 57

Saturday, October 15th 9:00-9:30

No.14 (503, 5F, PACIFICO Yokohama)

Ethics for clinical research

Chair : Shigetaka Asano  
Waseda University
Speaker : Taira Maekawa  
Department of Transfusion Medicine and Cell Therapy, Kyoto University Hospital

Educational Lecture 58

Saturday, October 15th 9:30-10:00

No.14 (503, 5F, PACIFICO Yokohama)

Primary immunodeficiency disease and hematology

Chair : Masao Kobayashi  
Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences
Speaker : Hirokazu Kanegane  
Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University

Educational Lecture 59

Saturday, October 15th 10:00-10:30

No.14 (503, 5F, PACIFICO Yokohama)

Childhood lymphoma

Chair : Yasuhide Hayashi  
Japanese Red Cross Gunma Blood Center
Speaker : Tetsuya Mori  
Department of Pediatrics, St. Marianna University School of Medicine

Educational Lecture 60

Saturday, October 15th 10:30-11:00

No.14 (503, 5F, PACIFICO Yokohama)

Genetic and epigenetic aberrations of pediatric leukemia and clinical applications

Chair : Etsuro Ito  
Department of Pediatrics, Hirosaki University Graduate School of Medicine
Speaker : Junko Takita  
The University of Tokyo, Graduate School of Medicine, Department of Pediatrics

Educational Lecture 61

Saturday, October 15th 13:20-13:50

No.14 (503, 5F, PACIFICO Yokohama)

Basics and applications of genome editing technology

Chair : Shuki Mizutani  
Tokyo Medical & Dental University / Kawasaki North Developmental Center
Speaker : Takashi Yamamoto  
Molecular Genetics Laboratory, Department of Mathematical and Life Sciences, Graduate School of Science, Hirosima University

Educational Lecture 62

Saturday, October 15th 13:50-14:20

No.14 (503, 5F, PACIFICO Yokohama)

Pathophysiology of MDS: genomic aberrations

Chair : Kazuya Shimoda  
Gastroenterology and Hematology, Faculty of Medicine, University of Miyazaki
Speaker : Motoshi Ichikawa  
Department of Hematology and Oncology, Dokkyo Medical University

Educational Lecture 63

Saturday, October 15th 14:20-14:50

No.14 (503, 5F, PACIFICO Yokohama)

Progress in the diagnosis of and therapy for MDS

Chair : Kazuma Ohyashiki  
Department of Hematology, Tokyo Medical University
Speaker : Yasuhito Nannya  
Kyoto University, Department of Pathology and Tumor Biology

Educational Lecture 64

Saturday, October 15th 14:50-15:20

No.14 (503, 5F, PACIFICO Yokohama)

Prophylactic strategies for invasive fungal infections after allogeneic hematopoietic stem cell transplantation

Chair : Yoji Ishida  
Hematology and Oncology, Internal Medicine, Iwate Medical University School of Medicine
Speaker : Yuki Asano-Mori  
Department of Hematology, Toranomon Hospital

Corporate Seminar

Thursday, October 13th 12:15ー13:00

LS1-2. The Role of Bruton Tyrosine Kinase Inhibitor in the Management of Relapsed and Refractory Chronic Lymphocytic Leukemia

No.2 (301+302, 3F, PACIFICO Yokohama)

Chair : Junji Suzumiya  
Shimane University Hospital Cancer Center
Speaker : Paolo Ghia  
Università Vita-Salute and Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy
Sponsor : Janssen Pharmaceutical K.K.

LS1-3. Optimizing ET Treatment

No.3 (303, 3F, PACIFICO Yokohama)

Chair : Norio Komatsu  
Department of Hematology, Juntendo University School of Medicine
Speaker : Jean-Jacques KILADJIAN  
Clinical Investigations Center, Saint-Louis Hospital - Paris Diderot University
Sponsor : Shire Japan KK

LS1-4. The Rapidly Changing Landscape of PTCL Management

No.4 (304, 3F, PACIFICO Yokohama)

Chair : Kensei Tobinai  
National Cancer Center
Speaker : Owen O’Connor  
Columbia University
Sponsor : Mundipharma K.K.

LS1-5. Ph+ ALL. The GIMEMA experience with TKI

No.5 (311+312, 3F, PACIFICO Yokohama)

Chair : Yuzuru Kanakura  
Osaka University Graduate School of Medicine
Speaker : Robin Foà  
Department of Cellular Biotechnologies and Hematology Policlinico Umberto I“― Sapienza”University
Sponsor : Bristol-Myers Squibb K.K.

Friday, October 14th 12:15ー13:00

LS2-2. The role and the potential benefits of rATG in allogeneic stem cell transplantation

No.2 (301+302, 3F, PACIFICO Yokohama)

Chair : Shuichi Taniguchi  
Department of Hematology, Toranomon Hospital
Speaker : Mohamad Mohty  
Department of Hematology, Hematology and cellular therapy Department, Hospital Saint-Antoine, and University Pierre & Marie Curie, Paris, France
Sponsor : Sanofi K.K.

LS2-3. Updates in the treatment of lower-risk MDS

No.3 (303, 3F, PACIFICO Yokohama)

Chair : Yasushi Miyazaki  
Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University
Speaker : Mikkael Sekeres  
Hematology and Oncology Cleveland Clinic
Sponsor : Kyowa Hakko Kirin Co., Ltd.

LS2-4. The current positioning of proteasome inhibitor in the treatment strategy of multiple myeloma

No.4 (304, 3F, PACIFICO Yokohama)

Chair : Itaru Matsumura  
Division of Hematology, Department of Internal Medicine, Kindai University School of Medicine
Speaker : Pieter Sonneveld  
Erasmus MC Cancer Institute Rotterdam The Netherlands
Sponsor : Janssen Pharmaceutical K.K. / Takeda Pharmaceutical Company Limited.

LS2-17. New standards of care for NDMM ―patients not eligible for transplant―

No.17 (Cannes & Nice, 3F, InterContinental Yokohama Grand)

Chair : Masahiro Abe  
The University of Tokushima Graduate School Institute of Health Biosciences, Department of Medicine and Bioregulatory Sciences
Speaker : Thierry Facon  
CHRU de Lille ―Hôpital Claude Huriez Rue Michel Polonovski, France
Sponsor : Celgene K.K.

Saturday, October 15th 8:00ー8:45

MS3-4. Mantle cell lymphoma; Molecular pathogenesis and prognostic factors

No.4 (304, 3F, PACIFICO Yokohama)

Chair : Hirokazu Nagai  
Department of Hematology / Oncology Research, Clinical Research Center NationalHospital Organization, Nagoya Medical Center
Speaker : Simon Rule  
Derriford Hospital, Plymouth, United Kingdom
Sponsor : Janssen Pharmaceutical K.K.

Saturday, October 15th 12:25ー13:10

LS3-2. New treatment paradigm for B-cell malignancies

No.2 (301+302, 3F, PACIFICO Yokohama)

Chair : Kiyohiko Hatake  
Cancer Institute Hospital
Speaker : John Seymour  
The Peter MacCallum Cancer Centre
Sponsor : AbbVie GK

LS3-5. Developing a Molecularly Targeted Therapy Approach to Multiple Myeloma

No.5 (311+312, 3F, PACIFICO Yokohama)

Chair : Kazuyuki Shimizu  
National Hospital Organization Higashinagoya National Hospital
Speaker : Robert Z. Orlowski  
The University of Texas MD Anderson Cancer Center
Sponsor : Fujimoto Pharmaceutical Corp.

LS3-8. Treatment Strategy to Low-grade B-cell Lymphoma

No.8 (413, 4F, PACIFICO Yokohama)

Chair : Tomohiro Kinoshita  
Department of Hematology and Cell Therapy, Aichi Cancer Center Hospital
Speaker : Jonathan W. Friedberg  
University of Rochester Wilmot Cancer Center, USA
Sponsor : SymBio Pharmaceuticals Limited / Eisai Co., Ltd.

LS3-11. The Emerging Role of HDAC Inhibitors in the New Era of Relapse and Refractory Multiple Myeloma Treatment

No.11 (419, 4F, PACIFICO Yokohama)

Chair : Chiaki Nakaseko  
Department of Hematology, Chiba University Hospital
Speaker : Paul G. Richardson  
Dana-Farber Cancer Institute, Boston, USA
Sponsor : Novartis Pharma K.K.

LS3-12. Do we have to eradicate CML stem cells or to achieve a deep molecular response ?

No.12 (501, 5F, PACIFICO Yokohama)

Chair : Koichi Miyamura  
Department of Hematology, Japanese Red Cross Nagoya Daiichi Hospital
Speaker : Philippe Rousselot  
University of Versailles St-Quentin-en-Yvelines, Versailles, France
Sponsor : Novartis Pharma K.K.

LS3-14. Future Direction of Folicular Lymphoma treatment based on MDACC experience and analysis

No.14 (503, 5F, PACIFICO Yokohama)

Chair : Tsukasaki Kunihiro  
Department of Hematology, National Cancer Center Hospital East
Speaker : Fredrick B. Hagemeister  
Internist and Professor of Medicine, Department of Lymphoma / Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
Sponsor : Chugai Pharmaceutical Co., Ltd.