Plenary Lecture 2

Saturday, Sept. 26
8:30〜9:30

Room A

Two-photon fluorescence and lifetime microscopy of neuronal activity, blood flow and oxygen dynamics in the mouse brain

Serge Charpak
Laboratory of Neurophysiology and New Microscopies, Inserm U1128, Paris Descartes University, Paris, France

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Plenary Lecture 3

Sunday, Sept. 27
15:15〜16:15

Room A

Angiogenesis revisited: Endothelial cell metabolism as a target?

Peter Carmeliet
Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center; Vlaams Instituut voor Biotechnologie, Department of Oncology, Katholieke Universiteit Leuven, Leuven, Belgium

Chair :

Shinichi Takahashi
Department of Neurology, Keio University School of Medicine, Tokyo, Japan

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Benjamin W. Zweifach Award

Saturday, Sept. 26
12:40〜13:25

Room A

D. Neil Granger
LSU Health Science Center – Shreveport, Shreveport, USA

Chair :

Rolando E. Rumbaut
Baylor College of Medicine, Houston, TX, USA

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Nishimaru-Tsuchiya Award

Saturday, Sept. 26
13:25〜14:10

Room A

Fitz-Roy E. Curry
Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, USA

Chair :

Hiroshi Nagata
Department of Internal Medicine, Keiyu Hospital, Yokohama, Japan

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Symposium 1: Pericytes and microcirculation

Friday, Sept. 25
14:25〜15:55

Room C1

Organizer/Chair :

Theodor Burdyga
The Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, UK

Co-chair :

Claire Peppiatt-Wildman
The Universities of Kent and Greenwich at Medway, UK

S1-1

Pericyte-containing retinovessels: The yin-yang of their physiology and pathobiology

Donald G. Puro
Departments of Ophthalmology & Vision Sciences and Molecular & Integrative Physiology, University of Michigan, USA

S1-2

Pacemaker role of pericytes in the microvasculature of visceral organs

Hikaru Hashitani
Department of Cell Physiology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan

S1-3

The evolving role of renal pericytes

Claire Peppiatt-Wildman
The Universities of Kent and Greenwich at Medway, UK

S1-4

How myocytes and pericytes integrate Ca2 signalling and tone in ureteric microvascular network in situ

Theodor Burdyga
The Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, UK

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Symposium 2: Recent advances in angiogenesis and lymphangiogenesis

Saturday, Sept. 26
16:05〜17:35

Room A

Organizer/Chair :

Yoshiaki Kubota
The Laboratory of Vascular Biology, Keio University, Tokyo, Japan

Co-chair :

Nobuyuki Takakura
Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

S2-1

Neuronal VEGF endocytosis triggers the programmed regression of hyaloid vessels

Yoshiaki Kubota (The Laboratory of Vascular Biology, Keio University, Tokyo, Japan)

S2-2

Apelin/APJ system regulates parallel juxtapositional alignment of arteries and veins

Nobuyuki Takakura (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan)

S2-3

Calcium imaging of endothelial cells helps understanding of angiogenic sprouting and tip-stalk determination

Naoki Mochizuki (Department of Cell Biology, Natl. Cerebr. & Cardiovasc. Ctr., Osaka, Japan)

S2-4

Roles of Signaling and Transcriptional Networks during Endothelial-to-Mesenchymal Transition

Tetsuro Watabe (Tokyo University of Pharmacy and Life Sciences, Japan)

Japanese Vascular Biology and Medicine Organization (JVBMO)

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Symposium 3:New Insights into immune cell regulation in microcirculation

Saturday, Sept. 26
16:05〜17:35

Room B1

Organizer/Chair :

Mariappan Muthuchamy
Texas A&M Health Science Center, USA

Co-chair :

Klaus Ley
La Jolla Institute for Allergy & Immunology, USA

S3-1

Neutrophil recruitment during inflammation

Markus Sperandio
Ludwig-Maximilians-Universitat, Germany

S3-2

Patrolling monocytes in atherosclerotic arteries

Klaus Ley
La Jolla Institute for Allergy & Immunology, USA

S3-3

Dendritic cell migration through afferent lymphatic vessels

Cornelia Halin
ETH Zurich, Switzerland

S3-4

Interactions Between Mast cells, MHC class II Positive Cells and Eosinophils by the Adult and Aged Lymphatic Vessels

Anatoliy A. Gashev
Department of Medical Physiology, College of Medicine, Texas A&M University Health Science Center, USA

The Microcirculatory Society and Kyowa Hakko Kirin California

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Symposium 4: Recent advances in cerebral microcirculation

Saturday, Sept. 26
16:05〜17:35

Room B2

Organizer/Chair :

Norio Tanahashi
Saitama Medical University International Medical Center, Japan

Co-chair :

Jing-Yan Han
Department of Integration of Traditional Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China

S4-1

Reendothelialization process by resident endothelial cells of the pial artery after the damage through a photochemical reaction

Yoshiaki Itoh
Department of Neurology, Osaka City University Graduate School of Medicine, Osaka, Japan

S4-2

Cilostazol inhibits leukocyte-endothelial cell interactions in murine microvessels after transient bilateral common carotid artery occlusion

Takuya Fukuoka
Saitama Medical University International Medical Center, Saitama, Japan

S4-3

Inhibitory effect of caffeic acid on ADP-induced cerebral thrombosis involves mitogen-activated protein kinases

Quan Li
Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China

S4-4

Ameliorating effects of Chinese herb compound preparation on cerebral microcirculatory disturbances and neuronal injuries after ischemia-reperfusion

Kai Sun
Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China

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Symposium 5:Endogenous mediators of endothelial barrier stability: Basic mechanisms and implications in human vascular disease and recovery

Sunday, Sept. 27
8:30〜10:00

Room A

Organizer/Chair :

Fitz-Roy E. Curry
Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, USA

Co-chair :

Rolf Reed
University of Bergen, Norway

S5-1

Evolving concepts in the regulation of endothelial barrier permeability. Tonic modulation of endothelial barrier functions and inflammatory cell trafficking

Fitz-Roy E. Curry
Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, USA

S5-2

Distinct Cell-specific Protective Actions of Atrial- and C-type Natriuretic Peptides in Acute Postischemic Microcirculatory Inflammation

Wen Chen
Institute of Physiology, University of Wuerzburg, Germany

S5-3

Atrial natriuretic peptide (ANP) down-regulates neutrophil recruitment on inflamed endothelium by reducing PMN deformability, while adhesive function is maintained

Scott I. Simon
Department of Biomedical Engineering,University of California, Davis, USA

S5-4

cAMP dependent pathways: New insights from Epac knockout mice

Stein Ove Doskeland
Department of Biomedicine, Faculty of medicine and dentistry, University of Bergen, Norway

S5-5

Regulation of cerebral post-ischemic inflammation by DAMPs and immune cells

Takashi Shichita
Department of Microbiology and Immunology, School of Medicine, Keio University, Japan

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Symposium 6:Metabolism and tumor microcirculation/angiogenesis

Sunday, Sept. 27
13:15〜14:45

Room A

Organizer/Chair :

Dai Fukumura
Massachusetts General Hospital and Harvard Medical School, Boston, USA

Co-chair :

Rakesh K. Jain
Massachusetts General Hospital, USA

S6-1

Angiogenesis revisited: Endothelial cell metabolism

Peter Carmeliet
Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center; Vlaams Instituut voor Biotechnologie, Department of Oncology, Katholieke Universiteit Leuven, Leuven, Belgium

S6-2

Looking back 30 years of discovery of the EPR effect of nanomedicine for treatment, imaging and next generation PDT for cancer: Problems, solutions and prospects

Hiroshi Maeda
Institute of Drug Delivery Science, Sojo University, Kumamoto, Japan

S6-3

Molecular targeting of tumor vasculatures

Gou Young Koh
Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea

S6-4

CO-sensitive membrane receptors regulating metabolic systems for regulating cancer proliferation and chemoresistance

Makoto Suematsu
Keio University School of Medicine, Tokyo, Japan

S6-5

Overcoming obesity-induced tumor progression and resistance to anti-angiogenic therapy

Dai Fukumura
Massachusetts General Hospital and Harvard Medical School, Boston, USA

Microcirculation

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Symposium 7: Structure and function of the endothelial glycocalyx

Sunday, Sept. 27
8:30〜10:00

Room B1

Chair :

Hans Vink
Department of Physiology, Maastricht University, The Netherlands

Co-chair :

Randal O. Dull
Department of Anesthesiology, University of Illinois at Chicago, College of Medicine, Chicago, USA

S7-1

Clinical assessment of glycocalyx: A tool to monitor vascular risk in patients?

Hans Vink
Department of Physiology, Maastricht University, The Netherlands

S7-2

The lung glycocalyx in pressure-dependent albumin transport and permeability

Randal O. Dull
Department of Anesthesiology, University of Illinois at Chicago, College of Medicine, Chicago, USA

S7-3

Genetic deletion of endothelial hyaluronan induces albuminuria and progressive glomerulopathy

Bernard van den Berg
The Einthoven Laboratory for Vasular Medicine, Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands

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Symposium 8:Microvascular remodeling in the coronary circulation

Sunday, Sept. 27
13 :15〜14:45

Room B1

Organizer/Chair :

Maria Siebes
University of Amsterdam, The Netherlands

Co-chair :

Fumihiko Kajiya
Kawasaki University of Medical Welfare, Japan

S8-1

Coronary microvascular remodeling and dysfunction in ischemic heart disease

Dirk J. Duncker
Experimental Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands

S8-2

Coronary microvascular remodeling - linking experimental findings in animals with observations in patients

Jos A. E. Spaan
Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, The Netherlands

S8-3

Coronary microvascular remodeling-model approaches

Yunlong Huo
The Department of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, China

S8-4

Coronary functional remodeling in Takotsubo cardiomyopathy

Vahagn Ohanyan
Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH, USA

Braedius Medical B.V.

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Symposium 9:The role of EDRF (NO and EDHF), H₂S and CO in microcirculation

Sunday, Sept. 27
8:30〜10:00

Room B2

Organizer/Chair :

Toyotaka Yada
Department of Medical Engineering, Kawasaki Medical School and Kawasaki University of Medical Welfare, Kurashiki, Japan

Co-chair :

Paul M. Vanhoutte
State Key Laboratory of Pharmaceutical Biotechnology & Department of Pharmacology & Pharmacy, Li Ka Shing Faculty of Medicine, the University of Hong Kong, China

S9-1

Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses

Shigeo Godo
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

S9-2

Carbon monoxide regulates directional biotransformation of glucose via protein arginine methylation

Takehiro Yamamoto
Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan

S9-3

Significance of nitric oxide synthases in the cardiovascular system: Lessons from triple nitric oxide synthases null mice

Masato Tsutsui
University of The Ryukyus, Japan

S9-4

NO the gate-keeper of endothelial function

Paul M. Vanhoutte
State Key Laboratory of Pharmaceutical Biotechnology & Department of Pharmacology & Pharmacy, Li Ka Shing Faculty of Medicine, the University of Hong Kong, China

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Symposium 10:Impact of mitochondrial function on vascular function and disease

Sunday, Sept. 27
13:15〜14:45

Room B2

Organizer/Chair :

Ulrich Pohl
Ludwig-Maximilians-University Munich, Germany

Co-chair :

John G. McCarron
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK

S10-1

Rapid determination of mitochondrial size, shape, position, density and motility in live fully-differentiated vascular smooth muscle cells reveal changes in hypertension and age.

John G. McCarron
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK

S10-2

Mitochondrial thioredoxin reductase and its importance for vascular homeostasis

Heike Beck
Walter Brendel Centre of Experimental Medicine, University of Munich, Munich, Germany

S10-3

The role of endothelial mitochondrial damage in microvascular rarefaction and fibrosis

Hazel H. Szeto
Research Program in Mitochondrial Therapeutics, Department of Pharmacology, Weill Cornell Medical College, New York, NY, USA

Journal of Vascular Research (JVR)

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Hybrid Symposium 1: Myeloid cell trafficking in disease

Friday, Sept. 25
9:45〜11:45

Room A

Organizer/Chair :

Catherine C. Hedrick
Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, USA

Co-chair :

Paul Kubes
University of Calgary, Calgary, Canada

HS1-1

Patrolling monocytes in vascular homeostasis

Catherine C. Hedrick
Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, USA

HS1-2

Fate and function of neutrophils in sterile injury

Cynthia J. Meininger
Texas A&M Health Science Center, USA

HS1-3

Tracking the origins of tumor-infiltrating monocytes using KikGR and Fucci technologies

Francis H.W. Shand
Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Japan

HS1-4

Recruitment of monocytes and macrophages to the site of sterile injury

Jing Wang
Department of Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada

HS1-5

Immune suppression after stroke

Connie H.Y. Wong
Centre for Inflammatory Diseases, Department of Medicine, Monash University, Australia

Kyowa Hakko Kirin California

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Hybrid Symposium 2: TRP channels and vascular disease

Friday, Sept. 25
14:25〜16:25

Room A

Organizer/Chair :

Scott Earley
Department of Pharmacology, University of Nevada School of Medicine, Reno, NV, USA

Co-chair :

Mark T. Nelson
Department of Pharmacology, University of Vermont, Burlington, VT, USA

HS2-1

The exquisite control of endothelial function by TRPV4 channels

Mark T. Nelson
Department of Pharmacology, University of Vermont, Burlington, VT, USA

HS2-2

Cerebrovascular protective effects of TRPA1 channels

Scott Earley
Department of Pharmacology, University of Nevada School of Medicine, Reno, NV, USA

HS2-3

TRPV4 sparklets in arteriolar smooth muscle

Luis Fernando Santana
Department of Physiology & Membrane Biology, University of California Davis, CA, USA

HS2-4

TRPV1-mediated Ca²⁺ influx and constriction of meningeal vasculature

George C. Wellman
Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT, USA

HS2-5

Extracellular histones activate local and propagating endothelial calcium signals

Daniel Collier
The Department of Pharmacology, University of Vermont, VT, USA

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Hybrid Symposium 3:Inflammation, oxidative stress and microRNAs in vascularisation

Friday, Sept. 25
9:45〜11:45

Room B1

Organizer/Chair :

Jozef Dulak
Jagiellonian University, Poland

Co-chair :

Ed van Bavel
Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, The Netherlands

HS3-1

Cross-talk between antioxidant genes and microRNAs in blood vessel formation

Jozef Dulak
Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Poland

HS3-2

Role of CLIC proteins in the regulation of pulmonary vascular inflammation and angiogenesis

Beata Wojciak-Stothard
Centre for Pharmacology and Therapeutics, Experimental Medicine, Imperial College London, London, UK

HS3-3

The intrinsic system that governs angiogenesis and stress resistance of vascular endothelium

Yasufumi Sato
Department of Vascular Biology, Institute of Development, Aging and Cancer, Tohoku University, Japan

HS3-4

Gene expression analysis in small arteries of spontaneously hypertensive rats: Evidence for ER stress

Ed van Bavel
Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, The Netherlands

HS3-5

VEGF knockdown in muscle improves recovery of blood flow after ischaemia

Maria J.C. Machado
Unit of Cancer Biology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, UK

Eupopean Vascular Biology Organization (EVBO)

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Hybrid Symposium 4: Metabolics, flowmotion and vascular control

Friday, Sept. 25
14:25〜16:25

Room B1

Organizer/Chair :

Axel R. Pries
Charité - Universitätsmedizin Berlin, Institute of Physiology, Berlin, Germany

Co-chair :

Roland Pittman
Virginia Commonwealth University, USA

HS4-1

Early insights linking muscle metabolism, vascular control and regulation of physiological angiogenesis

Stuart Egginton
University of Leeds, Leeds, UK

HS4-2

Methods for the investigation of flowmotion

Michelle A. Keske
Menzies Institute for Medical Research, University of Tasmania, Australia

HS4-3

Flow motion dynamics of blood flow and oxygenation

Geraldine Clough
Faculty of Medicine, University of Southampton, Southampton, UK

HS4-4

Regulation of local and conducted vasomotor tone in resistance-sized vessels

Lars J. Jensen
Department of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark

HS4-5

Mapping oxygen in the brain of awake mice

Serge Charpak
Laboratory of Neurophysiology and New Microscopies, Inserm U1128, Paris Descartes University, Paris, France

HS4-6

Metabolic regulation: Insights from simulation approaches

Axel R. Pries
Charité - Universitätsmedizin Berlin, Institute of Physiology, Berlin, Germany

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Hybrid Symposium 5:Mechanobiology: Roles of cellular and non-cellular elements

Friday, Sept. 25
9:45〜11:45

Room B2

Organizer/Chair :

Gerald Meininger
University of Missouri-Columbia, USA

Co-chair :

Michael A. Hill
Dalton Cardiovascular Reseach Center, University of Missouri, USA

HS5-1

Endothelial-smooth muscle cell interactions in the regulation of vascular tone

Kim A. Dora
University of Oxford, UK

HS5-2

Structural and cellular mechanisms underlying adaptive and pathological vascular responses to mechanical forces

Michael A. Hill
Dalton Cardiovascular Reseach Center, University of Missouri, USA

HS5-3

Mechanosensitive Gq/11-protein coupled receptors mediate myogenic vasoconstriction

Michael Mederos y Schnitzler
Ludwig-Maximilians-Universität München, Germany

HS5-4

Cytoskeletal reorganization: A fundamental process linked to vascular smooth muscle contraction

William C. Cole
Smooth Muscle Research Group, Department of Physiology & Pharmacology, University of Calgary, Calgary, Canada

HS5-5

Continuous serelaxin infusion alters circumferential wall stiffness but not myogenic tone of mesenteric resistance arteries in spontaneously hypertensive rats

Maria Jelinic
School of BioSciences, The University of Melbourne, VIC, Australia

MCS

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Hybrid Symposium 6:Bone microcirculation: A potential therapeutic target

Friday, Sept. 25
14:25〜16:25

Room B2

Organizer/Chair :

Nicola J. Brown
Microcirculation Research Group, Department of Oncology, University of Sheffield, UK

Co-chair :

Gabri Van der Pluijm
Leiden University Medical Center, Department of Urology, Leiden, The Netherlands

HS6-1

Coupling of angiogenesis and osteogenesis in bone

Anjali Kusumbe
Max Planck Institute for Molecular Biomedicine, Germany

HS6-2

BMP2 regulates both osteogenesis and angiogenesis during postnatal bone repair

Louis Gerstenfeld
Department of Orthopaedic Surgery and Molecular and Translational Medicine, Boston University School of Medicine, Boston, MA, USA

HS6-3

The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches

Gabri Van der Pluijm
Leiden University Medical Center, department of Urology, Leiden, The Netherlands

HS6-4

Novel approaches to investigating tumour-endothelial interactions

Nicola J. Brown
Microcirculation Research Group, Department of Oncology, University of Sheffield, UK

HS6-5

The importance of the perivascular niche in the early stage of breast cancer bone colonisation

Gloria Allocca
Department of Oncology, University of Sheffield, UK

Company of Biologists / Bone Research Society

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Hybrid Symposium 7:Microvascular plasticity and developmental priming: Impact on human health

Saturday, Sept. 26
9:35〜11:35

Room A

Organizer/Chair :

Geraldine Clough
Faculty of Medicine, University of Southampton, Southampton, UK

Co-chair :

Giovanni Mann
Kings College London, UK

HS7-1

Developmental aspects of a life course approach to healthy ageing

Mark A. Hanson
University of Southampton, Southampton, UK

HS7-2

Gestational xenobiotic exposures: Microvascular implications for the past, present, and future

Phoebe A. Stapleton
Department of Physiology and Pharmacology, West Virginia University, Morgantown, WV, USA

HS7-3

Heterogeneity of coronary vasculature and its complex development

Yuichiro Arima
Department of Cardiovascular Medicine, Kumamoto-University, Kumamoto, Japan

HS7-4

Retinal vascular imaging in early life: Insights into processes and risk of cardiovascular disease

Tien Wong
Duke-NUS Graduate Medical School Singapore, Singapore

The Journal of Physilogy

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Hybrid Symposium 8:Platelets: Key mediators of inflammation in the microcirculation

Saturday, Sept. 26
9:35〜11:35

Room B1

Organizer/Chair :

Rolando E. Rumbaut
Baylor College of Medicine, Houston, TX, USA

Co-chair :

Michael J. Hickey
Centre for Inflammatory Diseases, Department of Medicine, Monash University, Australia

HS8-1

Contributions of platelets to inflammation and neutrophil recruitment in the acutely inflamed glomerulus

Michael J. Hickey
Centre for Inflammatory Diseases, Department of Medicine, Monash University, Australia

HS8-2

Platelet-leukocyte interdependence in the inflamed microcirculation

Rolando E. Rumbaut
Baylor College of Medicine, Houston, TX, USA

HS8-3

Platelets are rapid responders to bacteremia

Paul Kubes
University of Calgary, Calgary, Canada

HS8-4

Platelet abnormalities in inflammatory bowel disease

D. Neil Granger
LSU Health Science Center – Shreveport, Shreveport, USA

HS8-5

Uridine triphosphates analogues as inhibitors of platelet aggregation

Muhammad Aslam
Department of Cardiology and Angiology, Justus Liebig University, Giessen, Germany

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Hybrid Symposium 9:What can mass spectrometric analysis offer? -Bridge between local metabolism and microvascular functions-

Saturday, Sept. 26
9:35〜11:35

Room B2

Organizer/Chair :

Per E. Andrén
Biomolecular Imaging and Proteomics, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden

Co-chair :

Jonathan V. Sweedler
University of Illinois at Urbana-Champaign, Urbana, IL,USA

HS9-1

Measuring the chemistry in tissues and individual cells using mass spectrometry

Jonathan V. Sweedler
University of Illinois at Urbana-Champaign, Urbana, IL,USA

HS9-2

Development of an imaging mass spectrometry technique for visualizing localized cellular signaling mediators in tissues

Yuki Sugiura
Department of Biochemistry, Keio University School of Medicine; Japan Science and Technology Agency, PRESTO Program, Tokyo, Japan

HS9-3

Visualization of metabolites localization at the micro-region using imaging mass spectrometry

Tsuyoshi Nakanishi
MS Business Unit, Shimadzu Corporation, Kyoto, Japan

HS9-4

Microscopic imaging mass spectrometry reveals a host-dependent mechanism for ammonia detoxification in the tumor-bearing liver of superimmunodeficient NOG mice

Mitsuyo Ohmura
Department of Biochemistry, Keio University, School of Medicine, Tokyo, Japan

HS9-5

Quantitative mass spectrometry imaging and profiling of neurotransmitters, neuropeptides and drugs directly in tissue sections

Per E. Andrén
Biomolecular Imaging and Proteomics, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden

JST, ERATO

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Hybrid Symposium 10:Building vascular networks: Determination, randomness and functional control

Sunday, Sept. 27
10:05〜12:05

Room A

Organizer/Chair :

Axel R. Pries
Charité - Universitätsmedizin Berlin, Institute of Physiology, Berlin, Germany

Co-chair :

Timothy W. Secomb
Department of Physiology, University of Arizona, Tucson, AZ, USA

HS10-1

Sprouting and splitting in organ vascular development

Valentin Djonov
lustitute of Anatomy, University of Bern, Bern, Switzerland

HS10-2

Formation and maintenance of microvascular networks by angiogenesis, remodeling and pruning: An integrative model

Timothy W. Secomb
Department of Physiology, University of Arizona, Tucson, AZ, USA

HS10-3

Relationship between microvascular blood flow and angiogenic factors in pre-eclampsia.

Anshuman Ghosh
School of Life Sciences, Kingston University, London, Kingston upon Thames, UK

HS10-4

Arterial-venous identity specification in pre-vascularized engineered implants requires perivascular cell recruitment and is impaired in diabetes

Sara S. Nunes de Vasconcelos
University Health Network, Toronto, Canada

ESM

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Hybrid Symposium 11:Microvascular plasticity in health and disease

Sunday, Sept. 27
10:05〜12:05

Room B1

Organizer/Chair :

Jay Hoying
University of Louisville, USA

Co-chair :

Mark Olfert
School of Medicine, West Virginia University, Morgantown, WV, USA

HS11-1

Hydrogen sulfide-nitric oxide stimulation of VEGF ischemic vascular remodeling

Chris Kevil
Departments of Pathology, Molecular and Cellular Physiology, and Cell Biology and Anatomy, LSU Health Shreveport, USA

HS11-2

Unveiling the cellular and molecular mechanism underlying vascular development by fluorescence-based bio-imaging in zebrafish

Shigetomo Fukuhara
Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Japan

HS11-3

Perivascular cell dynamics in the vasculatures of the eye

Tailoi Chan-Ling
Discipline of Anatomy & Histology, Sydney Medical School, Bosch Institute, The University of Sydney, Sydney, Australia

HS11-4

Adaptation of the coronary microcirculation in aging: Is regeneration possible?

Amanda J. LeBlanc
Department of Physiology, University of Louisville, Louisville, KY, USA

HS11-5

Angioregulatory peptide responses to physical deconditioning

Mark Olfert
School of Medicine, West Virginia University, Morgantown, WV, USA

PAGE TOP

Hybrid Symposium 12:Disease intervention: Targeting the microcirculation

Sunday, Sept. 27
10:05〜12:05

Room B2

Organizer/Chair :

Marianne Tare
Monash University, Australia

Co-chair :

Timothy V. Murphy
University of New South Wales, Australia

HS12-1

RGS5 integrates angiotensin II and PPAR vascular signaling to regulate blood pressure during pregnancy

Ruth Ganss
Harry Perkins Institute of Medical Research, The University of Western Australia, Western Australia, Australia

HS12-2

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice

Grant R. Drummond
Department of Pharmacology, Monash University, Clayton, Victoria, Australia; Department of Surgery, Monash Medical Centre, Southern Clinical School, Monash University, Clayton, Victoria, Australia

HS12-3

Further insight into vascular Kv7 channel function

Jennifer B. Stott
Institute of Cardiovascular & Cell Sciences, St George's University of London, London, UK

HS12-4

Serelaxin reduces endothelium-derived vasoconstrictor prostanoids in mesenteric arteries of spontaneously hypertensive rats

Chen Huei Leo
School of BioSciences, The University of Melbourne, Parkville, VIC, Australia

HS12-5

Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone

Thomas A. Jepps
Ion Channel Group, Department of Biomedical Sciences, University of Copenhagen, Denmark

HS12-6

Natriuretic peptides in the treatment of pulmonary hypertension: PDE2 inhibition augments their therapeutic capacity

Kristen J. Bubb
William Harvey Research Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, UK

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Young Investigators Symposium

Friday, Sept. 25
9:45〜11:15

Room C1

Organizer/Chair :

Shaun Sandow
Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Maroochydoore, Australia

Co-chair :

Angela Shore
University of Exeter Medical School, UK

YIS-1

VEGF-A165b ameliorates vascular dysfunction in diabetic retinopathy

Nikita Ved
Tumour and Vascular Biology Laboratories, Cancer Biology, School of Medicine, Queen's Medical Centre, Nottingham, UK

YIS-2

Exercise training ameliorates microvascular deterioration and VEGF signaling downregulation in aging rat brain

Sheepsumon Viboolvorakul
Department of Medical Science, Faculty of Science, Rangsit University, Pathum Thani, Thailand

YIS-3

Vascular Effects on Astrocytes Ca2+ Dynamics in Cerebral Cortex

Cam Ha T. Tran
Hotchkiss Brain Institute, University of Calgary, Alberta, Canada

YIS-4

Large-area surface-enhanced Raman spectroscopy imaging as a novel method to visualize alterations in small molecular metabolites in ischemic brain tissues

Megumi Shiota
Frontier Core-Technology Laboratories, R&D Management Headquarters, FUJIFILM Corporation, Japan

YIS-5

Dynamics of angiogenesis and blood flow in mouse long bone

Saravana Ramasamy
Max Planck Institute for Molecular Biomedicine, University of Muenster, Muenster, Germany

YIS-6

Clonidine restores pressor responsiveness to phenylephrine and
angiotensin II in ovine sepsis

Yugeesh R. Lankadeva
Florey Institute of Neuroscience and Mental Health, University of Melbourne; Department of Physiology, Monash University, Victoria, Australia

YIS-7

Complex signalling pathways determine the role of Kv7 channels in relaxations of the rat mesenteric artery

Jennifer B. Stott
Institute of Cardiovascular & Cell Sciences, St George's University of London, London UK

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Luncheon Seminar 1

Thursday, Sept. 24
11:30〜12:15

Room D

Chair :

Norio Tanahashi
Saitama Medical University International Medical Center, Saitama, Japan

LS1

New prospects of Non-vitamin K antagonist oral anticoagulants in the patients with atrial fibrillation: From the view of clinical question

Koichi Oki
Department of Neurology, Keio University School of Medicine, Tokyo, Japan

Bristol-Myers K.K. / Pfizer Japan Inc.

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Luncheon Seminar 2

Friday, Sept. 25
12:00〜12:45

Room A

Chair :

Norihiro Suzuki
Department of Neurology, Keio University School of Medicine, Tokyo, Japan

LS2

Metabolic systems in cancer and ischemia; mechanisms in search of treatments

Makoto Suematsu
Keio University School of Medicine, Japan

Otsuka Pharmaceutical Co., Ltd.

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Luncheon Seminar 3

Friday, Sept. 25
12:00〜12:45

Room B1

LS3

The FRET mouse: Activity imaging of signaling molecules in transgenic mice expressing FRET biosensor

Michiyuki Matsuda

Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Olympus Corporation

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Luncheon Seminar 4: Activated neutrophil and microcirculation

Friday, Sept. 25
12:00〜12:45

Room B2

Chair :

Kazuhide Higuchi
Osaka Medical College Hospital, Osaka, Japan

LS4-1

Granulocyte/monocyte apheresis (GMA) therapy for ulcerative colitis: Updated evidences

Yuji Naito
Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan

LS4-2

Microcirculation of mononuclear cells to the inflamed intestinal microvessels

Ryota Hokari
Department of Internal Medicine, National Defense Medical College, Saitama, Japan

JIMRO Co., Ltd.

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Luncheon Seminar 5

Saturday, Sept. 26
11:50〜12:35

Room A

Chair :

Norihiro Suzuki
Department of Neurology, Keio University School of Medicine, Japan

LS5

What is the severity of Dementia?

Yasuo Terayama
Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Japan

Eisai Co., Ltd.

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Luncheon Seminar 6

Thursday, Sept. 26
11:50〜12:35

Room B1

Chair :

Yuji Naito
Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan

LS6

Role of inflammatory activation for the symptom generation in the gut
- Gut microcirculation and functional gastrointestinal disorders (FGIDs)

Hidekazu Suzuki
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Kyoto, Japan

DAIICHI SANKYO COMPANY / LIMITED / AstraZeneca K.K.

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Luncheon Seminar 7

Saturday, Sept. 26
11:50〜12:35

Room B2

Chair :

Per E. Andrén
Biomolecular Imaging and Proteomics, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden

LS7

Basics of imaging mass spectrometry and applications in pharmacology using Mass Microscope

Shuichi Shimma
Laboratory of Bioresource Eng (Metabolomics), Department of Biotechnology, Division of Advanced Science and Biotechnology, Graduate School of Engineering, Osaka University, Osaka, Japan

SHIMADZU CORPORATION

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Evening Seminar: Clinical Impact of Microvascular Image using CT, MR and US

Thursday, Sept. 26
17:50〜18:50

Room A

Chair :

Makoto Suematsu
Keio University School of Medicine, Japan

ES-1

Visualizing Microcirculation by CT and MRI: Development of Perfusion Imaging

Masahiro Jinzaki
Department of Radiology, Keio University School of Medicine, Japan

ES-2

Seeing the unseen ~ clinical significance of Superb Microvascular Imaging~

Jiro Hata
Department of Endoscopy and Ultrasound, Kawasaki Medical University, Japan

Toshiba Medical Systems Corporation

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Luncheon Seminar 8

Sunday, Sept. 27
12:20〜13:05

Room A

Chair :

Masato Kasuga
National Center for Global Health and Medicine, Tokyo, Japan

LS8

Organ Memory and Vasculo-Metabolic Niche

Hiroshi Ito

Division of Endocrinology, Metabolism and Nephrology Department of Internal Medicine, Keio University School of Medicine, Japan

ONO PHARMACEUTICAL CO., LTD.

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Luncheon Seminar 9

Sunday, Sept. 27
12:20〜13:05

Room B1

Chair :

Hiroshi Nagata
Department of Internal Medicine, Keiyu Hospital, Kanagawa, Japan

LS9

Effects of SGLT2 inhibitors on renal function

Akira Nishiyama
Department of Pharmacology, Kagawa University Medical School, Kagawa, Japan

Taisho Toyama Pharmaceutical Co., Ltd.

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Luncheon Seminar 10

Sunday, Sept. 27
12:20〜13:05

Room B2

Chair :

Hideyuki Saya
Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, Japan

LS10

Regulation of Brain Microvascular Angiogenesis and Vascular Integrity

Calvin Kuo
Department of Medicine, Stanford University School of Medicine, Hematology Division, CA, USA

Chugai Pharmaceutical Co., Ltd.

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