Program at a Glance
| Date: | Saturday, November 1, 2025 |
| Venue: | Room K (503, 5F, PACIFICO YOKOHAMA Conference Center) |
Opening Remarks(9:15-9:20)
| Masahiro Toda | Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan |
Session 1(9:20-10:35)
| Chairs | D. Gareth R. Evans | University of Manchester, Manchester, UK |
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| Marco Giovannini | UCLA Comprehensive Neurofibromatosis and Schwannomatosis Program, Los Angeles, CA, USA |
| Speakers | New Classification and Genetics of NF2/SWN | |
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| D. Gareth R. Evans | University of Manchester, Manchester, UK | |
| Genotype/Phenotype Correlations and Prognosis in NF2/SWN | ||
| Yu Teranishi | Paris Brain Institute, Paris, France | |
| Genetic and Clinical Analysis of Japanese NF2-SWN Patients | ||
| Ryota Tamura | Keio University School of Medicine, Tokyo, Japan | |
| Preclinical Models of NF2-related Schwannomatosis | ||
| Marco Giovannini | UCLA Comprehensive Neurofibromatosis and Schwannomatosis Program, Los Angeles, CA, USA | |
Session 2(10:45-11:45)
| Chairs | D. Bradley Welling | Department of Otolaryngology Head and Neck Surgery, Harvard University, Boston, Massachusetts, USA |
|---|---|---|
| Naoki Oishi | Keio University, Tokyo, Japan |
| Speakers | Surgery and Hearing Preservation for NF2-related Vestibular Schwannoma | |
|---|---|---|
| D. Bradley Welling | Department of Otolaryngology Head and Neck Surgery, Harvard University, Boston, Massachusetts, USA | |
| Intraoperative Cochlear Nerve Monitoring in the Resection of Vestibular Schwannoma | ||
| Naoki Oishi | Otology and Audiology Center, Keio University Hospital, Tokyo, Japan | |
| Strategy of Hearing Restoration in Patients with NF2-related Schwannomatosis | ||
| Hao Wu | Shanghai 9th People's Hospital (Shanghai Jiao Tong University School of Medicine), Shanghai, China | |
Luncheon Seminar(11:55-12:55)
Update on the Treatment of NF2-related Schwannomatosis, Including Surgical Approach
| Chair | Masazumi Fujii | Department of Neurosurgery, Fukushima Medical University, Fukushima, Fukushima, Japan |
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| Speakers | Recent Treatment Strategies for NF2-related Tumors | |
|---|---|---|
| Takeo Goto | Department of Neurosurgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan | |
| Personalized Surgical Decision-making in NF2-related Schwannomatosis: Customizing Care in a Complex Landscape | ||
| Soichi Oya | Department of Neurosurgery, Gunma University Graduate School of Medicine, Gunma, Japan | |
Session 3(13:10-14:50)
| Chairs | Michel Kalamarides | Hopital Pitie-Salpetriere, Deparment of Neurosurgery, Paris, France |
|---|---|---|
| P. Leia Nghiemphu | Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA |
| Speakers | Comprehensive Clinical Management of NF2/SWN Patients | |
|---|---|---|
| P. Leia Nghiemphu | Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA | |
| Surgical Management of NF2-related Vestibular Schwannomas | ||
| Michihiro Kohno | Department of Neurosurgery, Tokyo Medical University, Tokyo, Japan | |
| Functional Preservation and Hearing Rehabilitation in Vestibular Schwannoma and NF2 Surgery: Role of Real-Time AEDNAP/FREMAP Monitoring and Implant | ||
| Hirofumi Nakatomi | Department of Neurosurgery, International University of Health and Welfare, Japan | |
| Meningioma and Ependymoma Surgery in NF2/SWN and Associated Translational Research | ||
| Michel Kalamarides | Hopital Pitie-Salpetriere, Deparment of Neurosurgery, Paris, France | |
| Effectiveness of Microanatomy-based Stereotactic Radiosurgery of Vestibular Schwannomas for Hearing Preservation in Patients with Neurofibromatosis Type 2 related Schwannomatosis | ||
| Motohiro Hayashi | Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan | |
| Treatment Strategies for NF2-related Vestibular Schwannoma Patients in Indonesia | ||
| Agung Budi Sutiono | Department of Neurosurgery Hasan Sadikin Hospital / Padjadjaran University, Bandung, Indonesia | |
Session 4(15:00-16:00)
| Chairs | Scott Plotkin | Massachusetts General Hospital / Harvard Medical School, Boston, Massachusetts, USA |
|---|---|---|
| Masahiro Toda | Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan |
| Speakers | Therapeutic Approaches and Clinical Trials for NF2/SWN | |
|---|---|---|
| Scott Plotkin | Massachusetts General Hospital / Harvard Medical School, Boston, Massachusetts, USA | |
| A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Trial Evaluating the Efficacy and Safety of Bevacizumab in Patients with NF2-Related Schwannomatosis Vestibular Schwannoma (BeatNF2 Trial) | ||
| Masazumi Fujii | Department of Neurosurgery, Fukushima Medical University, Fukushima, Fukushima, Japan | |
| Immunotherapy for Neurofibromatosis Type 2-related Schwannomatosis (NF2-SWN) | ||
| Masahiro Toda | Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan | |
Closing Remarks(16:00-16:05)
| Marco Giovannini | UCLA Comprehensive Neurofibromatosis and Schwannomatosis Program, Los Angeles, CA, USA |