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Program
Invited Lecture
Invited Lecture 1
Saturday, April 19, 10:35-11:35 Room 1
| Chair | Susumu Ishida（Hokkaido Univ, Japan） |
| Speaker | A Nexus of Genes, Aging and Environment in Age-related Macular Degeneration Anand Swaroop（National Eye Inst, National Inst Health, USA） |
Invited Lecture 2
Friday, April 18, 11:30-12:30 Room 1
| Chair | Takeo Fukuchi（Niigata Univ, Japan） |
| Speaker | The functional consequences of glaucoma, and how we might alter them for our patients Pradeep Ramulu（Johns Hopkins Wilmer Eye Inst, USA） |
Symposium
Symposium 1
Latest Genomic Research for Precision Medicine
Thursday, April 17, 9:00-10:20 Room 1
| Organizers | Masahiro Miyake（Kyoto Univ, Japan） |
Shinji Ueno（Hirosaki Univ, Japan） |
| Speakers | The path to RPE65 gene therapy and to the future Maeda Akiko（Kobe City Eye Hosp, Japan） |
Latest research and future perspective in gene therapy for Leber Hereditary Optic Neuropathy Kaori Ueda（Kobe Univ, Japan） |
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Genetic characteristics of inherited retinal dystrophy in Japanese population Kensuke Goto（Osaka Univ, Premium Research Institute for Human Metaverse Medicine (PRIMe), Japan） |
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Genomic Analysis of Pachychoroid Spectrum Disease Yuki Mori（Kyoto Univ, Japan） |
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Towards precision medicine: Genomic analysis of complex eye diseases Masato Akiyama（Kyushu Univ, Japan） |
Symposium 2
＜Basic Research Seminar＞Advanced Research on AI Applications Across Fields
Thursday, April 17, 10:50-12:10 Room 1
| Organizers | Motokazu Tsujikawa（Osaka Univ, Japan） |
Toru Nakazawa（Tohoku Univ, Japan） |
| Speakers | Innovations in Medical AI: Shaping the Future of Medicine and Healthcare Through Human-AI Synergy Eiryo Kawakami（Chiba Univ, Japan/RIKEN, Japan） |
Robotalization of life science with Maholo LabDroid and AI Genki Kanda（RIKEN BDR, Japan） |
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Frontiers of Vision and Language: Bridging Images and Texts by Deep Learning Yoshitaka Ushiku（OSX; OMRON SINICX Corp., Japan） |
Symposium 3
Science has Great Beauty 1. Cutting Edge of the Sensory Bioimaging for Visualizing Various Invisible Biological Phenomena
Thursday, April 17, 14:00-15:20 Room 1
| Organizers | Shinsuke Shibata（Div of Microscopic Anatomy, Niigata Univ, Japan） |
Takeo Fukuchi（Niigata Univ, Japan） |
| Speakers | Visualizing the "pain sensation" with using human iPS cell derived sensory nerve organoids Shinsuke Shibata（Div of Microscopic Anatomy, Niigata Univ, Japan） |
Demonstrating "taste sensing system" with newly developed taste bud organoids Ken Iwatsuki（Tokyo Univ of Agriculture, Japan） |
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Exploring the "humidity sensing system" in the skin and its physiological responses Mariko Hara-Chikuma（Dept of Pharmacology, Keio Univ, Japan） |
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Visualization of the structure and vibrations of the inner ear in a live animal model for hearing loss Hiroshi Hibino（Dept Pharmacol, Osaka Univ, Japan） |
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Myopia control by non-visual light responses Toshihide Kurihara（Keio Univ, Japan） |
Symposium 4
Science has Great Beauty 2. Talking with Legend: Cornea
Thursday, April 17, 15:35-16:55 Room 1
| Organizers | Yuichi Hori（Toho Univ, Japan） |
Takefumi Yamaguchi（Tokyo Dent Coll, Ichikawa, Japan） |
| Speakers | Harmonizing clinical and basic research for Fuchs endothelial corneal dystrophy Sayo Maeno（Osaka Univ, Japan） |
Scientific Mysteries and Clinical Significance of the Corneal Nerve Yoshiaki Tagawa（Hokkaido Univ, Japan） |
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Stem Cell Therapy and Disease Modeling in vitro -Perspectives on Corneal Regeneration and Aging- Emi Inagaki（Keio Univ, Japan） |
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Beauty in corneal surgery, optics and aqueous microenvironment Takefumi Yamaguchi（Tokyo Dent Coll, Ichikawa, Japan） |
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Medical Science and Future Realities in Corneal and Ocular Surface Research Shigeru Kinoshita（Kyoto Pref Univ, Japan） |
Symposium 5
Recent Advances of Ocular Drug Delivery Systems
Thursday, April 17, 9:00-10:20 Room 2
| Organizers | Yasushi Kitaoka（St Marianna Univ, Japan） |
Yasuyuki Takai（Osada Eye Cl, Japan / Masuda Red Cross Hosp, Japan） |
| Speakers | Development process of ocular drug delivery Kazuhito Yamada（Santen Pharmaceutical Co., Ltd, Japan） |
Design of drug-loaded contact lens for sustainable ocular drug delivery Noriaki Nagai（Kindai Univ, Japan） |
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DDS for glaucoma drug treatment Yasushi Kitaoka（St Marianna Univ, Japan） |
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Liposomal ophthalmic solution for VEGF-siRNA delivery to the retina Yuuki Takashima（Juntendo Univ, Japan） |
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Development and the possibility of drug delivery system for retinal diseases Kazuaki Kadonosono（Yokohama City Univ, Japan） |
Symposium 6
Neural Regulation in Ocular Surface Homeostasis and the Pathophysiology of Its Impairment
Thursday, April 17, 10:50-12:10 Room 2
| Organizers | Masatoshi Hirayama（Keio Univ, Japan） |
Kaoru Araki-Sasaki（Kansai Med Univ, Japan） |
| Speakers | The sensory nervous system mediates pollen shell-stimulated induction of goblet cell-associated antigen passage Meiko Kimura（Juntendo Univ, Urayasu, Japan/Juntendo Univ, Atopy (Allergy) Research Ctr, Japan） |
TRP channels are important in corneal wound healing Yuka Okada（Wakayama Med Univ, Kihoku, Japan） |
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Elucidating Neuropathic pain in the cornea Yoshiaki Tagawa（Hokkaido Univ, Japan） |
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Dry eye and neuropathic pain Yuto Tei（Dept. Physiol. Fac. Med. Toho Univ, Japan/Toho Univ, Omori, Japan） |
Symposium 7Japanese Session
Thursday, April 17, 14:00-15:20 Room 2
Symposium 8
Translational Research in Retinal and Optic Nerve Diseases
Thursday, April 17, 15:35-16:55 Room 2
| Organizers | Toshihide Kurihara（Keio Univ, Japan） |
Teruyo Kida（Osaka Med and Pharm Univ, Japan） |
| Speakers | The forefront of development in gene therapy for vision restoration Yusaku Katada（Keio Univ, Japan/Restore Vision, Inc., Japan） |
The developmental history of glaucoma eye drops and new foundational research Megumi Honjo（Tokyo Univ, Japan） |
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Strategies of Drug Discovery for Novel Therapeutics in Ophthalmic Diseases Hanako Ikeda（Osaka Med and Pharm Univ, Japan） |
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Development of AI for Fundus Imaging Devices and Current Challenges Hidenori Takahashi（Tsukuba Univ, Japan/Jichi Med Univ, Japan） |
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Advancements in Digitally Assisted Vitreoretinal Surgery, Robotics and AI Shin Tanaka（Yokohama City Univ, Japan） |
Symposium 9
New Perspectives in Understanding the Pathophysiology of Allergic Conjunctival Diseases
Thursday, April 17, 9:00-10:20 Room 3
| Organizers | Dai Miyazaki（Tottori Univ, Japan） |
Kenichi Namba（Hokkaido Univ, Japan） |
| Speakers | Early-onset factors in allergic conjunctivitis development revealed by the Japan Environment and Children's Study Tamaki Sumi（Kochi Univ, Japan） |
Eosinophil diversity and lipid mediators in controlling inflammation and allergy Makoto Arita（Div of Physiological Chemistry and Metabolism, Keio Univ Faculty of Pharmacy, Japan/Keio Univ WPI-Bio2Q, Japan/RIKEN Ctr for Integrative Medical Sciences, Japan/Graduate School of Medical Life Science, Yokohama City Univ, Japan） |
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Neuropeptide CGRP-producing memory Th2 cells cooperate with somatosensory neurons to induce conjunctival itch Nobuyuki Ebihara（Juntendo Univ, Urayasu, Japan） |
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Periostin: a target for therapeutic agents against allergic conjunctival disease Kenji Izuhara（Saga Univ, Div of Allergy Dept of Biomolecular Sciences, Japan） |
Symposium 10
Treatment of Pediatric Eye Diseases in Comparison with Adult Cases
Thursday, April 17, 10:50-12:10 Room 3
| Organizers | Shunji Kusaka（Kindai Univ, Japan） |
Koh-Hei Sonoda（Kyushu Univ, Japan） |
| Speakers | Novel Amblyopia Treatment for Children with Dichoptic Training Using a Virtual Reality Head-Mounted Display Takeshi Morimoto（Osaka Univ, Japan） |
Cataract Surgery Daijiro Kurosaka（Iwate Med Univ, Japan） |
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Treatment for pediatric uveitis Satoshi Yamana（Kyushu Univ, Japan） |
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Retinopathy of Prematurity Chiharu Iwahashi（Kindai Univ, Japan） |
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Optic Neuritis in Pediatric and Adult Populations Sotaro Mori（Kobe Univ, Japan） |
Symposium 11
Myopia Research Update ~from Infants to Adults~
Thursday, April 17, 14:00-15:20 Room 3
| Organizers | Tae Igarashi-Yokoi（Tokyo Metropolitan Hiroo Hosp, Japan） |
Yuta Ueno（Tsukuba Univ, Japan） |
| Speakers | Genetics and epidemiology of myopia Masahiro Miyake（Kyoto Univ, Japan） |
Myopia management in infants Sachiko Nishina（National Ctr for Child Health and Development, Japan） |
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Latest topics in clinical research on myopia Hidemasa Torii（Keio Univ, Japan） |
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Effect of Repeated Low-Level Red-Light Therapy for Myopia Control Junfuku Lee（Science Tokyo, Japan） |
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Surgical treatment for myopic foveoschisis Yasushi Ikuno（Ikuno Eye Ctr, Japan） |
Symposium 12
Elucidating the Mechanism of Presbyopia and a New Adventure for Treatment
Thursday, April 17, 15:35-16:55 Room 3
| Organizers | Kazuno Negishi（Keio Univ, Japan） |
Eri Kubo（Kanazawa Med Univ, Japan） |
| Speakers | Regenerative Medicine for the Crystalline Lens: Prospects for the Future Naoki Yamamoto（Fujita Health Univ, Japan） |
New Developments in Presbyopia Treatment: Exploring the Potential of Pharmacotherapy Yosuke Nakazawa（Fac Pharm, Keio Univ, Japan） |
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Evaluation of Changes in Optical Properties of the Presbyopic Lens Using Optical Simulation Takushi Kawamorita（Kitasato Univ, Japan） |
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The Latest Technologies and Prospects in Surgical Correction for Presbyopia Hiroyuki Arai（Queen's Eye Cl, Japan） |
Symposium 13Japanese Session
Friday, April 18, 9:00-10:20 Room 1
Symposium 14
Science has Great Beauty 4. Talking with Legend: Glaucoma
Friday, April 18, 15:30-16:50 Room 1
| Organizers | Makoto Aihara（Tokyo Univ, Japan） |
Nobuyuki Shoji（Kitasato Univ, Japan） |
| Speakers | Pioneering epitranscriptome in ophthalmology Akiko Ogawa（Tohoku Univ, Japan/Kumamoto Univ, Japan） |
Investigating the mechanisms of intraocular pressure elevation Hotaka Nemoto（Tokyo Univ, Japan） |
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Challenges in elucidating the pathophysiology of glaucoma using molecular epidemiological approach Akiko Hanyuda（Keio Univ, Japan） |
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Disc hemorrhage: revisiting the phenomenon Takashi Nishida（UCSD, USA） |
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Era of mitomycin: How can we justify glaucoma surgery? Tetsuya Yamamoto（Kaiya Eye Cl, Japan） |
Symposium 15
Curing Neuro-Ophthalmological Diseases with Biologics!
Friday, April 18, 9:00-10:20 Room 2
| Organizers | Ai Kozaki（Olympia Eye Hosp, Japan） |
Hitoshi Ishikawa（Dept of Orthoptics and Visual Science, School of Allied Health Sciences, Kitasato Univ, Japan） |
| Speakers | Biologics for Neuro-ophthalmological diseases -overview- Satoshi Ueki（Niigata Univ, Japan） |
Biologics to prevent recurrence of refractory optic neuritis Yohei Takahashi（Tokyo Women's Med Univ, Japan/Kitasato Univ, Japan） |
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Novel molecularly targeted agents for myasthenia gravis Takeshi Kezuka（KEZUKA Eye Cl, Japan/Tokyo Med Univ, Japan） |
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Biologics and thyroid ophthalmopathy Masashi Mimura（Hyogo Med Coll, Japan） |
Symposium 16
Protecting Children's Vision -Part IV- Myopia
Friday, April 18, 15:30-16:50 Room 2
| Organizers | Masako Shirane（Shirane Ophthalmology Cl, Japan） |
Kazuhisa Sugiyama（Keiju Med Ctr Hokuriku Glaucoma Cl, Japan） |
| Speakers | MEXT's policies on children's eye health Shuntaro Tsutsumi（Health Education and Shokuiku Division, Elementary and Secondary Education Bureau, Ministry of Education, Culture, Sports, Science and Technology, Japan） |
Prevention of myopia progression in children Kyoko Ohno-Matsui（Science Tokyo, Japan） |
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Dangerous diseases from pathological myopia Yasushi Ikuno（Ikuno Eye Ctr, Japan） |
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Educational activities for early detection and prevention of myopia Nagako Kondo（Miyake Eye Hosp, Japan） |
Symposium 17
Ocular Tumors Treatment Strategy Update
Friday, April 18, 9:00-10:20 Room 3
| Organizers | Yoshihiko Usui（Tokyo Med Univ, Japan） |
Tatsuya Yunoki（Toyama Univ, Japan） |
| Speakers | Treatment Strategies for Malignant Tumors of the Eyelid Jun Ominato（Niigata univ, Japan） |
Malignant tumors of the conjunctiva Satoru Kase（Nara Pref Med Univ, Japan） |
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Vitreo retinal lymphoma Mizuki Tagami（Osaka Metro Univ, Japan） |
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Treatment Strategies for Orbital Malignancies Mika Tanabe（Kyushu Univ, Japan） |
Symposium 18
Clinical Application of AI and Its Challenges
Saturday, April 19, 9:00-10:20 Room 1
| Organizers | Tetsuro Oshika（Tsukuba Univ, Japan） |
Nami Masuhara（Chigasaki Municipal Hosp, Japan） |
| Speakers | AI for assessing surgical skills and outcomes Shameema Sikder（Wilmer Eye Inst, Johns Hopkins Univ, Baltimore, USA） |
Development and future prospects of public AI models using JOI Registry Masahiro Oda（Information Technology Ctr, Nagoya Univ, Japan/Graduate School of Informatics, Nagoya Univ, Japan） |
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Fundus AI for health check-up Masahiro Miyake（Kyoto Univ, Japan） |
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AI Hospital Project: Challenges and Prospects Ryo Kawasaki（Public Health, Univ. Osaka, Japan） |
Symposium 19
Approaching the Pathogenesis of Ocular Infections
Saturday, April 19, 9:00-10:20 Room 2
| Organizers | Daisuke Todokoro（Gunma Univ, Japan） |
Ken Fukuda（Kochi Univ, Japan） |
| Speakers | The role of pathogenic factors in bacterial keratitis caused by Gram-negative rods Hidenori Inoue（Ehime Univ, Japan） |
Interaction between bacterial toxin and alarmin in the pathogenesis of Staphylococcus aureus keratitis Isana Nakajima（Kochi Univ, Japan） |
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Mechanism and Role of Corneal Lymphangiogenesis in Bacterial Keratitis Akitomo Narimatsu（Tokyo Med Univ, Japan） |
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Attempts to explore pathogens by metagenomic analysis in ocular surface diseases of unknown cause Fumika Hotta（Kindai Univ, Japan） |
Symposium 20Japanese Session
Saturday, April 19, 9:00-10:20 Room 3
Symposium 21Japanese Session
Sunday, April 20, 10:40-12:00 Room 2
International Symposium
International Symposium 1
Next Generation Approaches to Retinal Diseases
Friday, April 18, 15:30-16:50 Room 7
| Organizers | Yoko Ozawa（Fujita Med Innovation Ctr Tokyo, Japan） |
Ayumi Ouchi（Juntendo Univ, Urayasu, Japan） |
| Speakers | Role of Inflammation and Senescence in AMD and Retinal Neurodegeneration Rajendra S. Apte（Washington Univ, USA） |
Innate immune memory and Age-related macular degeneration Masayuki Hata（Kyoto Univ, Japan） |
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Retinal Microglia and Neurovascular Microenvironment in Diabetic Retinopathy Ayumi Ouchi（Juntendo Univ, Urayasu, Japan） |
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Stemming Vision Loss with Stem (and other types of) Cells Martin Friedlander（Dept of Cellular and Molecular Biology, Scripps Research, USA/The Lowy Med Research Inst USA/Div of Ophthalmology, Dept of Surgery, Scripps Cl, USA） |
International Symposium 2
Updates on Glaucoma Diagnostics
Saturday, April 19, 9:00-10:20 Room 7
| Organizers | Hitomi Saito（Tokyo Univ, Japan） |
Miki Atsuya（Aichi Med Univ, Japan） |
| Speakers | Update on Intraocular Pressure Monitoring Kaweh Mansouri（Glaucoma Ctr, Swiss Visio, Montchoisi Cl, Lausanne, Switzerland/Univ of Colorado, Denver, USA） |
High-Resolution Imaging and Artificial Intelligence in Glaucoma: Recent Discoveries and Clinical Perspectives Jin Wook Jeoung（Seoul National Univ, Seoul, Korea/Seoul National Univ Hosp, Seoul, Korea） |
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Update on visual field testing Hiroki Nomoto（Kindai Univ, Japan） |
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Update on Risk Factors for Glaucoma Akiko Hanyuda（Keio Univ, Japan） |
The International Crosstalk Symposium by Young Ophthalmologists
Friday, April 18, 9:00-10:20 Room 7
| Chairs | Hirokazu Sakaguchi（Hiroshima Univ, Japan） |
Kazuno Negishi（Keio Univ, Japan） |
| Speakers | Streptococcus Suis Endogenous Endophthalmitis in a Patient with Meningitis Ngan-Ha Nguyen（Hanoi Med Univ, Vietnam） |
Accuracy of Integrated AI Grading Using Handheld Retinal Imaging in a Community Diabetic Retinopathy Screening Program Recivall P Salongcay（Eye and Vision Inst, The Med City, Metro Manila, Philippines/Ctr for Public Health, Queen’s Univ, Belfast, UK） |
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CHAC1 as a novel contributor of ferroptosis in retinal pigment epithelial cells with oxidative damage Di Wu（Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Ctr of the Second Affiliated Hosp, Zhejiang Univ, China） |
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Retinal artery and vein occlusion risks after COVID-19 or COVID-19 vaccination Yong Joon Kim（Inst of Vision Research, Severance Hosp, Yonsei Univ, Republic of Korea） |
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Dilated Choroidal Vascular Channels in Pachychoroid Neovasculopathy Jia-Horung Hung（National Cheng Kung Univ Hosp, National Cheng Kung Univ, Tainan, Taiwan/Spencer Ctr for Vision Research, Byers Eye Inst, Stanford Univ, Palo Alto, CA, USA） |
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En Face OCT Detects Preretinal Abnormal Tissues Before and After Internal Limiting Membrane Peeling in Macular Hole Yuichiro Ishida（Aichi Med Univ, Japan） |
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Role of Adrenomedullin 2/Intermedin in the Pathogenesis of Neovascular Age-Related Macular Degeneration Shinji Kakihara（Shinshu Univ, Japan） |
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Involvement of AIM in the phagocytosis of trabecular meshwork cells and IOP Hotaka Nemoto（Tokyo Univ, Japan） |
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Characteristics related to vision loss after successful PDT for eyes with central serous chorioretinopathy Ryoh Funatsu（Kagoshima Univ, Japan） |
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Novel findings of the retinoid cycle in RDH5-related Fundus Albipunctatus patients with Dunaliella supplementation Kei Mizobuchi（Jikei Univ, Japan） |
